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C-band heteromorphism in breast cancer patients

Berger, Roland; Bernheim, Alain; Kristoffersson, Ulf LU ; Mitelman, Felix LU and Olsson, Håkan LU (1985) In Cancer Genetics and Cytogenetics1979-01-01+01:002011-01-01+01:00 18(1). p.37-42
Abstract

The pattern of heteromorphism in the C-band-positive constitutive heterochromatin of human chromosomes #1, #9, and #16 was studied in peripheral lymphocytes of 54 breast cancer patients and 78 control individuals. The parameters of the heterochromatic regions analyzed were relative size, symmetry-asymmetry within homologous pairs, and prevalence of inversions. Significant differences between the two groups were found in C-band size of chromosomes #1, #9, and #16 and in incidence of inversions on chromosomes #1 and #9. Significant differences were noted between premenopausal and postmenopausal cancer patients in regard to inversions on chromosome #9 and between familial and sporadic patients in regard to C-band size on chromosome #16.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Cancer Genetics and Cytogenetics1979-01-01+01:002011-01-01+01:00
volume
18
issue
1
pages
6 pages
publisher
Elsevier
external identifiers
  • scopus:0022257061
ISSN
0165-4608
DOI
10.1016/0165-4608(85)90037-8
language
English
LU publication?
yes
id
01d90705-95ff-455b-98cb-de8348f68032
date added to LUP
2018-12-12 08:48:24
date last changed
2019-01-06 14:19:45
@article{01d90705-95ff-455b-98cb-de8348f68032,
  abstract     = {<p>The pattern of heteromorphism in the C-band-positive constitutive heterochromatin of human chromosomes #1, #9, and #16 was studied in peripheral lymphocytes of 54 breast cancer patients and 78 control individuals. The parameters of the heterochromatic regions analyzed were relative size, symmetry-asymmetry within homologous pairs, and prevalence of inversions. Significant differences between the two groups were found in C-band size of chromosomes #1, #9, and #16 and in incidence of inversions on chromosomes #1 and #9. Significant differences were noted between premenopausal and postmenopausal cancer patients in regard to inversions on chromosome #9 and between familial and sporadic patients in regard to C-band size on chromosome #16.</p>},
  author       = {Berger, Roland and Bernheim, Alain and Kristoffersson, Ulf and Mitelman, Felix and Olsson, Håkan},
  issn         = {0165-4608},
  language     = {eng},
  month        = {01},
  number       = {1},
  pages        = {37--42},
  publisher    = {Elsevier},
  series       = {Cancer Genetics and Cytogenetics1979-01-01+01:002011-01-01+01:00},
  title        = {C-band heteromorphism in breast cancer patients},
  url          = {http://dx.doi.org/10.1016/0165-4608(85)90037-8},
  volume       = {18},
  year         = {1985},
}