MLL/GAS7 fusion in a pediatric case of t(11;17)(q23;p13)-positive precursor B-cell acute lymphoblastic leukemia
(2006) In Haematologica 91(9). p.1287-1288- Abstract
- AML/GAS7, resulting from t(11;17)(q23;p13), has been reported in one case of treatment-related acute myeloid leukemia (AML). We present a de novo case of t(11;17)-positive pediatric acute lymphoblastic leukemia. Fluorescent in situ hybridization and reverse transcriptase polymerase chain reaction analyses revealed an MLL/GAS7 chimera identical to the one previously described in AML. The molecular genetic features of MLL/GAS7 and the clinical impact of t(11;17) are discussed.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/394180
- author
- Panagopoulos, Ioannis LU ; Lilljebjörn, Henrik LU ; Strömbeck, Bodil LU ; Hjorth, Lars LU ; Olofsson, Tor LU and Johansson, Bertil LU
- organization
- publishing date
- 2006
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- GAS7, MLL, ALL, translocation, fusion
- in
- Haematologica
- volume
- 91
- issue
- 9
- pages
- 1287 - 1288
- publisher
- Ferrata Storti Foundation
- external identifiers
-
- wos:000240353100028
- pmid:16956839
- scopus:33748782773
- ISSN
- 1592-8721
- language
- English
- LU publication?
- yes
- id
- 03de4f16-4961-4d57-bb67-216411318133 (old id 394180)
- alternative location
- http://www.haematologica.org/cgi/content/abstract/91/9/1287
- date added to LUP
- 2016-04-01 16:14:11
- date last changed
- 2022-01-28 18:17:37
@article{03de4f16-4961-4d57-bb67-216411318133, abstract = {{AML/GAS7, resulting from t(11;17)(q23;p13), has been reported in one case of treatment-related acute myeloid leukemia (AML). We present a de novo case of t(11;17)-positive pediatric acute lymphoblastic leukemia. Fluorescent in situ hybridization and reverse transcriptase polymerase chain reaction analyses revealed an MLL/GAS7 chimera identical to the one previously described in AML. The molecular genetic features of MLL/GAS7 and the clinical impact of t(11;17) are discussed.}}, author = {{Panagopoulos, Ioannis and Lilljebjörn, Henrik and Strömbeck, Bodil and Hjorth, Lars and Olofsson, Tor and Johansson, Bertil}}, issn = {{1592-8721}}, keywords = {{GAS7; MLL; ALL; translocation; fusion}}, language = {{eng}}, number = {{9}}, pages = {{1287--1288}}, publisher = {{Ferrata Storti Foundation}}, series = {{Haematologica}}, title = {{MLL/GAS7 fusion in a pediatric case of t(11;17)(q23;p13)-positive precursor B-cell acute lymphoblastic leukemia}}, url = {{http://www.haematologica.org/cgi/content/abstract/91/9/1287}}, volume = {{91}}, year = {{2006}}, }