Gastrointestinal symptoms in women with endometriosis and microscopic colitis in comparison to irritable bowel syndrome : A cross-sectional study
(2021) In Turkish Journal of Gastroenterology 32(10). p.819-827- Abstract
Background: Gastrointestinal (GI) symptoms similar to irritable bowel syndrome (IBS) are often present in women with endometriosis and microscopic colitis (MC). The objective of this study was to estimate GI symptoms in IBS, endometriosis, and MC, to compare the clinical expression of the diseases. Methods: Women with IBS, endometriosis, and MC were identified by diagnosis codes at a tertiary center. The patients had to complete the visual analog scale for IBS to estimate specific GI symptoms. Women fulfilling Rome III criteria for IBS were diagnosed as IBS (n = 109) and divided into subgroups depending on predominating symptoms. Women diagnosed with endometriosis (n = 158) and MC (n = 88) were evaluated whether they also fulfilled the... (More)
Background: Gastrointestinal (GI) symptoms similar to irritable bowel syndrome (IBS) are often present in women with endometriosis and microscopic colitis (MC). The objective of this study was to estimate GI symptoms in IBS, endometriosis, and MC, to compare the clinical expression of the diseases. Methods: Women with IBS, endometriosis, and MC were identified by diagnosis codes at a tertiary center. The patients had to complete the visual analog scale for IBS to estimate specific GI symptoms. Women fulfilling Rome III criteria for IBS were diagnosed as IBS (n = 109) and divided into subgroups depending on predominating symptoms. Women diagnosed with endometriosis (n = 158) and MC (n = 88) were evaluated whether they also fulfilled the Rome III criteria for IBS. Results: Women with IBS experienced aggravated abdominal pain, diarrhea, bloating and flatulence, nausea and vomiting, the urgency to defecate, the sensation of incomplete evacuation and intestinal symptom's influence on daily life, and impaired psychological well-being, compared to women with endometriosis. When patients with endometriosis also fulfilled the criteria for IBS, all symptoms in the 2 cohorts, except intestinal symptom's influence on daily life, were equal. Women with IBS or diarrhea-predominated IBS experienced aggravated abdominal pain, bloating and flatulence, intestinal symptom's influence on daily life, and impaired psychological well-being compared to MC, but at equal levels as MC with IBS-like symptoms. Conclusions: Women with IBS generally experience aggravated GI symptoms and impaired psychological well-being compared to endometriosis and MC. Patients with endometriosis or MC in combination with IBS express similar symptoms as patients with sole IBS.
(Less)
- author
- Ek, Malin LU ; Roth, Bodil LU ; Bengtsson, Mariette LU and Ohlsson, Bodil LU
- organization
- publishing date
- 2021
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Endometriosis, Gastrointestinal symptoms, Irritable bowel syndrome, Microscopic colitis, Visceral hypersensitivity
- in
- Turkish Journal of Gastroenterology
- volume
- 32
- issue
- 10
- pages
- 9 pages
- publisher
- Turkish Society of Gastroenterology
- external identifiers
-
- pmid:34787086
- scopus:85120037569
- ISSN
- 1300-4948
- DOI
- 10.5152/tjg.2020.19583
- language
- English
- LU publication?
- yes
- id
- 04aa8698-3d1f-414a-be72-72a6edb74b8d
- date added to LUP
- 2021-12-15 14:25:00
- date last changed
- 2024-06-15 22:54:28
@article{04aa8698-3d1f-414a-be72-72a6edb74b8d,
abstract = {{<p>Background: Gastrointestinal (GI) symptoms similar to irritable bowel syndrome (IBS) are often present in women with endometriosis and microscopic colitis (MC). The objective of this study was to estimate GI symptoms in IBS, endometriosis, and MC, to compare the clinical expression of the diseases. Methods: Women with IBS, endometriosis, and MC were identified by diagnosis codes at a tertiary center. The patients had to complete the visual analog scale for IBS to estimate specific GI symptoms. Women fulfilling Rome III criteria for IBS were diagnosed as IBS (n = 109) and divided into subgroups depending on predominating symptoms. Women diagnosed with endometriosis (n = 158) and MC (n = 88) were evaluated whether they also fulfilled the Rome III criteria for IBS. Results: Women with IBS experienced aggravated abdominal pain, diarrhea, bloating and flatulence, nausea and vomiting, the urgency to defecate, the sensation of incomplete evacuation and intestinal symptom's influence on daily life, and impaired psychological well-being, compared to women with endometriosis. When patients with endometriosis also fulfilled the criteria for IBS, all symptoms in the 2 cohorts, except intestinal symptom's influence on daily life, were equal. Women with IBS or diarrhea-predominated IBS experienced aggravated abdominal pain, bloating and flatulence, intestinal symptom's influence on daily life, and impaired psychological well-being compared to MC, but at equal levels as MC with IBS-like symptoms. Conclusions: Women with IBS generally experience aggravated GI symptoms and impaired psychological well-being compared to endometriosis and MC. Patients with endometriosis or MC in combination with IBS express similar symptoms as patients with sole IBS.</p>}},
author = {{Ek, Malin and Roth, Bodil and Bengtsson, Mariette and Ohlsson, Bodil}},
issn = {{1300-4948}},
keywords = {{Endometriosis; Gastrointestinal symptoms; Irritable bowel syndrome; Microscopic colitis; Visceral hypersensitivity}},
language = {{eng}},
number = {{10}},
pages = {{819--827}},
publisher = {{Turkish Society of Gastroenterology}},
series = {{Turkish Journal of Gastroenterology}},
title = {{Gastrointestinal symptoms in women with endometriosis and microscopic colitis in comparison to irritable bowel syndrome : A cross-sectional study}},
url = {{http://dx.doi.org/10.5152/tjg.2020.19583}},
doi = {{10.5152/tjg.2020.19583}},
volume = {{32}},
year = {{2021}},
}