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Visual Analysis of Zebrafish Behavior

Palmér, Tobias LU ; Åström, Karl LU ; Enqvist, Olof and Petersson, Per LU (2016) 2016 23rd International Conference on Pattern Recognition (ICPR 2016)
Abstract
There is significant interest from the medical and
neuroscience communities for studying the behavior of zebrafish
larvae, particularly in the context of drug testing. In this paper, we
propose a method for analyzing the behavior of zebrafish larvae
in a high-throughput system using automatic image analysis.
Specifically, algorithms for estimating the poses of the larvae in
video recordings are presented. The pose estimation results are
subsequently used to estimate kinematic parameters, segment the
discretized movement into swim bouts (short bursts of movement)
and to categorize the swim bouts into a number of classes. The
distributions of bout classes are analyzed over time for different
doses... (More)
There is significant interest from the medical and
neuroscience communities for studying the behavior of zebrafish
larvae, particularly in the context of drug testing. In this paper, we
propose a method for analyzing the behavior of zebrafish larvae
in a high-throughput system using automatic image analysis.
Specifically, algorithms for estimating the poses of the larvae in
video recordings are presented. The pose estimation results are
subsequently used to estimate kinematic parameters, segment the
discretized movement into swim bouts (short bursts of movement)
and to categorize the swim bouts into a number of classes. The
distributions of bout classes are analyzed over time for different
doses of amphetamine and apomorphine and compared to control
groups. Preliminary results are presented indicating that the
proposed method is able to measure the effects of pharmacological
manipulations in the zebrafish larvae. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to conference
publication status
published
subject
pages
4 pages
conference name
2016 23rd International Conference on Pattern Recognition (ICPR 2016)
conference location
Cancún, Mexico
conference dates
2016-12-04 - 2016-12-08
language
English
LU publication?
yes
id
0597a4c7-3b16-47c1-aa79-5ce75cd5a609
alternative location
http://homepages.inf.ed.ac.uk/rbf/VAIB16PAPERS/vaibpalmer.pdf
date added to LUP
2016-10-29 15:29:04
date last changed
2019-04-30 11:20:17
@misc{0597a4c7-3b16-47c1-aa79-5ce75cd5a609,
  abstract     = {There is significant interest from the medical and<br/>neuroscience communities for studying the behavior of zebrafish<br/>larvae, particularly in the context of drug testing. In this paper, we<br/>propose a method for analyzing the behavior of zebrafish larvae<br/>in a high-throughput system using automatic image analysis.<br/>Specifically, algorithms for estimating the poses of the larvae in<br/>video recordings are presented. The pose estimation results are<br/>subsequently used to estimate kinematic parameters, segment the<br/>discretized movement into swim bouts (short bursts of movement)<br/>and to categorize the swim bouts into a number of classes. The<br/>distributions of bout classes are analyzed over time for different<br/>doses of amphetamine and apomorphine and compared to control<br/>groups. Preliminary results are presented indicating that the<br/>proposed method is able to measure the effects of pharmacological<br/>manipulations in the zebrafish larvae.},
  author       = {Palmér, Tobias and Åström, Karl and Enqvist, Olof and Petersson, Per},
  language     = {eng},
  location     = {Cancún, Mexico},
  month        = {12},
  pages        = {4},
  title        = {Visual Analysis of Zebrafish Behavior},
  year         = {2016},
}