Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Dynamic right ventricular and atrial volume responses to exercise in endurance-trained and untrained healthy individuals

Östenson, Björn LU orcid ; Ostenfeld, Ellen LU orcid ; Edlund, Jonathan LU orcid ; Arheden, Håkan LU and Steding-Ehrenborg, Katarina LU (2026) In PLOS ONE 21(5 May).
Abstract

Aims Left ventricular (LV) function is enhanced during exercise in endurance-trained (ET) compared to untrained (UT) healthy individuals. However, the volume responses of the right ventricle (RV), left atrium (LA), and right atrium (RA) during exercise have not been studied in the same subject simultaneously and while standardizing for the respiratory influence on cardiac volumes. The aim was therefore to investigate how the four-chambered heart responds to exercise in ET and UT healthy individuals using exercise real-time cardiac magnetic resonance imaging (CMR) while controlling for effects of respiration. Materials and methods Twenty ET (9 women) and 13 UT healthy individuals matched for age and sex underwent CMR at rest and during... (More)

Aims Left ventricular (LV) function is enhanced during exercise in endurance-trained (ET) compared to untrained (UT) healthy individuals. However, the volume responses of the right ventricle (RV), left atrium (LA), and right atrium (RA) during exercise have not been studied in the same subject simultaneously and while standardizing for the respiratory influence on cardiac volumes. The aim was therefore to investigate how the four-chambered heart responds to exercise in ET and UT healthy individuals using exercise real-time cardiac magnetic resonance imaging (CMR) while controlling for effects of respiration. Materials and methods Twenty ET (9 women) and 13 UT healthy individuals matched for age and sex underwent CMR at rest and during moderate and vigorous exercise. LV and RV end-diastolic and end-systolic volumes (EDV and ESV), stroke volumes (SV) and maximal and minimal LA and RA volumes (LAVmax, RAVmax and LAVmin, RAVmin) were measured at end expiration. Results LVEDV and LVESV decreased during exercise in both groups. RVEDV and RVESV decreased during exercise in ET but was unchanged in UT. LAVmax and LAVmin were unchanged from rest to vigorous exercise in both groups. RAVmax decreased during exercise in ET whilst RAVmin was unchanged, and RAVmax and RAVmin were unchanged in UT. Thus, the RV and RA volume responses during exercise differed between ET and UT.

(Less)
Please use this url to cite or link to this publication:
author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
PLOS ONE
volume
21
issue
5 May
article number
e0347745
publisher
Public Library of Science (PLoS)
external identifiers
  • scopus:105039332337
  • pmid:42160269
ISSN
1932-6203
DOI
10.1371/journal.pone.0347745
language
English
LU publication?
yes
id
06a121f3-d614-422a-bc4d-9198095310ac
date added to LUP
2026-08-13 17:15:39
date last changed
2026-09-10 19:04:54
@article{06a121f3-d614-422a-bc4d-9198095310ac,
  abstract     = {{<p>Aims Left ventricular (LV) function is enhanced during exercise in endurance-trained (ET) compared to untrained (UT) healthy individuals. However, the volume responses of the right ventricle (RV), left atrium (LA), and right atrium (RA) during exercise have not been studied in the same subject simultaneously and while standardizing for the respiratory influence on cardiac volumes. The aim was therefore to investigate how the four-chambered heart responds to exercise in ET and UT healthy individuals using exercise real-time cardiac magnetic resonance imaging (CMR) while controlling for effects of respiration. Materials and methods Twenty ET (9 women) and 13 UT healthy individuals matched for age and sex underwent CMR at rest and during moderate and vigorous exercise. LV and RV end-diastolic and end-systolic volumes (EDV and ESV), stroke volumes (SV) and maximal and minimal LA and RA volumes (LAV<sub>max</sub>, RAV<sub>max</sub> and LAV<sub>min</sub>, RAV<sub>min</sub>) were measured at end expiration. Results LVEDV and LVESV decreased during exercise in both groups. RVEDV and RVESV decreased during exercise in ET but was unchanged in UT. LAV<sub>max</sub> and LAV<sub>min</sub> were unchanged from rest to vigorous exercise in both groups. RAV<sub>max</sub> decreased during exercise in ET whilst RAV<sub>min</sub> was unchanged, and RAV<sub>max</sub> and RAV<sub>min</sub> were unchanged in UT. Thus, the RV and RA volume responses during exercise differed between ET and UT.</p>}},
  author       = {{Östenson, Björn and Ostenfeld, Ellen and Edlund, Jonathan and Arheden, Håkan and Steding-Ehrenborg, Katarina}},
  issn         = {{1932-6203}},
  language     = {{eng}},
  number       = {{5 May}},
  publisher    = {{Public Library of Science (PLoS)}},
  series       = {{PLOS ONE}},
  title        = {{Dynamic right ventricular and atrial volume responses to exercise in endurance-trained and untrained healthy individuals}},
  url          = {{http://dx.doi.org/10.1371/journal.pone.0347745}},
  doi          = {{10.1371/journal.pone.0347745}},
  volume       = {{21}},
  year         = {{2026}},
}