Dietary adherence is not dependent on the mode of diagnosis in children with coeliac disease
Hård af Segerstad, Elin M. LU
; Avender, Helena
; Kornhall, Ludvig
and Agardh, Daniel
LU
(2024)
In Acta Paediatrica, International Journal of Paediatrics
- Abstract
Aim: To compare the adherence to gluten-free diet between children with serology-based and biopsy-proven coeliac disease. Methods: Medical records were retrospectively reviewed in 257 Swedish children diagnosed with coeliac disease between 2012 and 2019 at a tertiary hospital. Adherence to a gluten-free diet was systematically assessed by trained dietitians at follow-up. Mixed models were used to analyse the dietary adherence by mode of diagnosis (serology-based vs. biopsy-proven). Results: After mean 6.3 (SD 2.4) years, there was neither a difference in the dietary adherence over time depending on the mode of diagnosis (OR 0.64 [95% confidence interval (CI) 0.26, 1.60], p = 0.342), nor if coeliac disease was detected in screening... (More)
Aim: To compare the adherence to gluten-free diet between children with serology-based and biopsy-proven coeliac disease. Methods: Medical records were retrospectively reviewed in 257 Swedish children diagnosed with coeliac disease between 2012 and 2019 at a tertiary hospital. Adherence to a gluten-free diet was systematically assessed by trained dietitians at follow-up. Mixed models were used to analyse the dietary adherence by mode of diagnosis (serology-based vs. biopsy-proven). Results: After mean 6.3 (SD 2.4) years, there was neither a difference in the dietary adherence over time depending on the mode of diagnosis (OR 0.64 [95% confidence interval (CI) 0.26, 1.60], p = 0.342), nor if coeliac disease was detected in screening studies (OR 0.74 [95% CI 0.25, 2.17], p = 0.584) or in risk-groups (OR 1.01 [95% CI 0.26, 3.91], p = 0.991) compared to clinically detected diagnosis. Non-adherence to a gluten-free diet increased with age (OR 1.19 [95% CI 1.06, 1.33], p = 0.003). There was no difference in the proportion of patients improving their dietary adherence from non-adherent to adherent over time (p = 0.322). Conclusion: Mode of diagnosis did not influence the dietary adherence in Swedish children with coeliac disease, although adherence to a gluten-free diet was inversely associated with increasing age.
(Less)
- author
- Hård af Segerstad, Elin M.
LU
; Avender, Helena
; Kornhall, Ludvig
and Agardh, Daniel
LU
- organization
- publishing date
- 2024
- type
- Contribution to journal
- publication status
- in press
- subject
- keywords
- compliance, dietitian, gluten-free diet, tissue transglutaminase antibodies
- in
- Acta Paediatrica, International Journal of Paediatrics
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:38656690
- scopus:85191341576
- ISSN
- 0803-5253
- DOI
- 10.1111/apa.17248
- language
- English
- LU publication?
- yes
- id
- 075e3f42-a055-474c-a0b8-7b669d0714ac
- date added to LUP
- 2024-05-06 13:29:45
- date last changed
- 2024-05-07 03:00:39
@article{075e3f42-a055-474c-a0b8-7b669d0714ac,
abstract = {{<p>Aim: To compare the adherence to gluten-free diet between children with serology-based and biopsy-proven coeliac disease. Methods: Medical records were retrospectively reviewed in 257 Swedish children diagnosed with coeliac disease between 2012 and 2019 at a tertiary hospital. Adherence to a gluten-free diet was systematically assessed by trained dietitians at follow-up. Mixed models were used to analyse the dietary adherence by mode of diagnosis (serology-based vs. biopsy-proven). Results: After mean 6.3 (SD 2.4) years, there was neither a difference in the dietary adherence over time depending on the mode of diagnosis (OR 0.64 [95% confidence interval (CI) 0.26, 1.60], p = 0.342), nor if coeliac disease was detected in screening studies (OR 0.74 [95% CI 0.25, 2.17], p = 0.584) or in risk-groups (OR 1.01 [95% CI 0.26, 3.91], p = 0.991) compared to clinically detected diagnosis. Non-adherence to a gluten-free diet increased with age (OR 1.19 [95% CI 1.06, 1.33], p = 0.003). There was no difference in the proportion of patients improving their dietary adherence from non-adherent to adherent over time (p = 0.322). Conclusion: Mode of diagnosis did not influence the dietary adherence in Swedish children with coeliac disease, although adherence to a gluten-free diet was inversely associated with increasing age.</p>}},
author = {{Hård af Segerstad, Elin M. and Avender, Helena and Kornhall, Ludvig and Agardh, Daniel}},
issn = {{0803-5253}},
keywords = {{compliance; dietitian; gluten-free diet; tissue transglutaminase antibodies}},
language = {{eng}},
publisher = {{Wiley-Blackwell}},
series = {{Acta Paediatrica, International Journal of Paediatrics}},
title = {{Dietary adherence is not dependent on the mode of diagnosis in children with coeliac disease}},
url = {{http://dx.doi.org/10.1111/apa.17248}},
doi = {{10.1111/apa.17248}},
year = {{2024}},
}