Parkinson disease and growth factors — is GDNF good enough?
(2019) In Nature Reviews Neurology 15. p.312-312- Abstract
- Previous open-label trials testing glial cell line-derived neurotrophic factor (GDNF) family ligands in Parkinson disease have shown promising clinical effects. However, in placebo-controlled trials, the treatments have failed. A new randomized placebo-controlled trial of intraputamenal delivery of GDNF designed to resolve this conundrum has again failed to do just that.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/076d6a52-1fe1-4b9b-862a-5aeb0358d032
- author
- Kirkeby, Agnete LU and Barker, Roger
- organization
- publishing date
- 2019-04-04
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Nature Reviews Neurology
- volume
- 15
- pages
- 314 pages
- publisher
- Nature Publishing Group
- external identifiers
-
- pmid:30948845
- scopus:85064011594
- ISSN
- 1759-4766
- DOI
- 10.1038/s41582-019-0180-6
- language
- English
- LU publication?
- no
- id
- 076d6a52-1fe1-4b9b-862a-5aeb0358d032
- alternative location
- https://www.nature.com/articles/s41582-019-0180-6
- date added to LUP
- 2019-11-28 13:24:52
- date last changed
- 2022-05-11 23:05:28
@misc{076d6a52-1fe1-4b9b-862a-5aeb0358d032,
abstract = {{Previous open-label trials testing glial cell line-derived neurotrophic factor (GDNF) family ligands in Parkinson disease have shown promising clinical effects. However, in placebo-controlled trials, the treatments have failed. A new randomized placebo-controlled trial of intraputamenal delivery of GDNF designed to resolve this conundrum has again failed to do just that.}},
author = {{Kirkeby, Agnete and Barker, Roger}},
issn = {{1759-4766}},
language = {{eng}},
month = {{04}},
pages = {{312--312}},
publisher = {{Nature Publishing Group}},
series = {{Nature Reviews Neurology}},
title = {{Parkinson disease and growth factors — is GDNF good enough?}},
url = {{http://dx.doi.org/10.1038/s41582-019-0180-6}},
doi = {{10.1038/s41582-019-0180-6}},
volume = {{15}},
year = {{2019}},
}