Probiotics and Blueberry Attenuate the Severity of Dextran Sulfate Sodium (DSS)-Induced Colitis.
(2008) In Digestive Diseases and Sciences 53. p.2464-2473- Abstract
- We studied the anti-inflammatory properties of probiotic strains and blueberry in a colitis model. The disease activity index (DAI) was significantly lower on days 9 and 10 in all groups compared to the colitis control. Myeloperoxidase (MPO) and bacterial translocation to the liver and to the mesenteric lymph nodes (MLN) decreased significantly in all groups compared to colitis control. Cecal Enterobacteriaceae count decreased significantly in blueberry with and without probiotics compared to the other groups. Lactobacillus plantarum reisolated from the cecal content in the presence of blueberry, contrary to Lactobacillus fermentum. Colonic MDA decreased significantly in all groups, except the L. fermentum group, compared to the colitis... (More)
- We studied the anti-inflammatory properties of probiotic strains and blueberry in a colitis model. The disease activity index (DAI) was significantly lower on days 9 and 10 in all groups compared to the colitis control. Myeloperoxidase (MPO) and bacterial translocation to the liver and to the mesenteric lymph nodes (MLN) decreased significantly in all groups compared to colitis control. Cecal Enterobacteriaceae count decreased significantly in blueberry with and without probiotics compared to the other groups. Lactobacillus plantarum reisolated from the cecal content in the presence of blueberry, contrary to Lactobacillus fermentum. Colonic MDA decreased significantly in all groups, except the L. fermentum group, compared to the colitis control. The cecal concentration of acetic, propionic, and butyricbutyric acid was significantly higher in the L. plantarum group, while the L. fermentum group yielded the highest concentration of lactic acid compared with all other groups. Lactobacillus plantarum DSM 15313, Lactobacillus fermentum 35D, and blueberry alone and in combination improve the DAI, reduce bacterial translocation, and reduce inflammation. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1041935
- author
- Osman, Nadia LU ; Adawi, Diya LU ; Ahrné, Siv LU ; Jeppsson, Bengt LU and Molin, Göran LU
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Digestive Diseases and Sciences
- volume
- 53
- pages
- 2464 - 2473
- publisher
- Springer
- external identifiers
-
- pmid:18274903
- wos:000258601800024
- scopus:50249139552
- pmid:18274903
- ISSN
- 1573-2568
- DOI
- 10.1007/s10620-007-0174-x
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Emergency medicine/Medicine/Surgery (013240200), Department of Food Technology (011001210), Surgery Research Unit (013242220), Applied Nutrition and Food Chemistry (011001300), Food Technology (011001017)
- id
- 05e04bd4-b34b-4742-9fc7-c6237babcd8b (old id 1041935)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/18274903?dopt=Abstract
- date added to LUP
- 2016-04-01 11:43:43
- date last changed
- 2023-11-25 11:19:52
@article{05e04bd4-b34b-4742-9fc7-c6237babcd8b, abstract = {{We studied the anti-inflammatory properties of probiotic strains and blueberry in a colitis model. The disease activity index (DAI) was significantly lower on days 9 and 10 in all groups compared to the colitis control. Myeloperoxidase (MPO) and bacterial translocation to the liver and to the mesenteric lymph nodes (MLN) decreased significantly in all groups compared to colitis control. Cecal Enterobacteriaceae count decreased significantly in blueberry with and without probiotics compared to the other groups. Lactobacillus plantarum reisolated from the cecal content in the presence of blueberry, contrary to Lactobacillus fermentum. Colonic MDA decreased significantly in all groups, except the L. fermentum group, compared to the colitis control. The cecal concentration of acetic, propionic, and butyricbutyric acid was significantly higher in the L. plantarum group, while the L. fermentum group yielded the highest concentration of lactic acid compared with all other groups. Lactobacillus plantarum DSM 15313, Lactobacillus fermentum 35D, and blueberry alone and in combination improve the DAI, reduce bacterial translocation, and reduce inflammation.}}, author = {{Osman, Nadia and Adawi, Diya and Ahrné, Siv and Jeppsson, Bengt and Molin, Göran}}, issn = {{1573-2568}}, language = {{eng}}, pages = {{2464--2473}}, publisher = {{Springer}}, series = {{Digestive Diseases and Sciences}}, title = {{Probiotics and Blueberry Attenuate the Severity of Dextran Sulfate Sodium (DSS)-Induced Colitis.}}, url = {{http://dx.doi.org/10.1007/s10620-007-0174-x}}, doi = {{10.1007/s10620-007-0174-x}}, volume = {{53}}, year = {{2008}}, }