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Evaluation of circulating immune complex-like material for development of skin reactions in connection with penicillin therapy

Ahlstedt, S; Bjursten, Lars Magnus LU ; Hanson, L A; Lidin-Janson, G; Mobacken, H and Belin, L (1981) In International Archives of Allergy and Applied Immunology 64(2). p.195-200
Abstract
The levels of immune complex-like material in serum from 18 patients in connection with skin eruptions appearing during penicillin therapy were determined with a modified ELISA. Immune complex-like material could only be shown in the serum of 3 out of the 17 patients. However, according to ELISA results, the complexes appeared without the simultaneous presence of penicilloyl-specific antibodies. Neither could penicilloyl-specific antibodies be recorded in 9 patient treated with parenteral penicillin without adverse reactions. 3 of these patients had immune complex-like material in their serum. It was concluded that immune complex-like material with penicilloyl specificity is not likely to contribute to the development of skin eruptions... (More)
The levels of immune complex-like material in serum from 18 patients in connection with skin eruptions appearing during penicillin therapy were determined with a modified ELISA. Immune complex-like material could only be shown in the serum of 3 out of the 17 patients. However, according to ELISA results, the complexes appeared without the simultaneous presence of penicilloyl-specific antibodies. Neither could penicilloyl-specific antibodies be recorded in 9 patient treated with parenteral penicillin without adverse reactions. 3 of these patients had immune complex-like material in their serum. It was concluded that immune complex-like material with penicilloyl specificity is not likely to contribute to the development of skin eruptions often seen in connection with penicillin treatment. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
International Archives of Allergy and Applied Immunology
volume
64
issue
2
pages
195 - 200
publisher
Karger
external identifiers
  • pmid:7461855
  • scopus:0019428194
ISSN
0020-5915
language
English
LU publication?
yes
id
26c80c54-0d2f-451c-beb1-80d35580f997 (old id 1102801)
date added to LUP
2008-08-13 15:19:49
date last changed
2017-01-01 07:05:42
@article{26c80c54-0d2f-451c-beb1-80d35580f997,
  abstract     = {The levels of immune complex-like material in serum from 18 patients in connection with skin eruptions appearing during penicillin therapy were determined with a modified ELISA. Immune complex-like material could only be shown in the serum of 3 out of the 17 patients. However, according to ELISA results, the complexes appeared without the simultaneous presence of penicilloyl-specific antibodies. Neither could penicilloyl-specific antibodies be recorded in 9 patient treated with parenteral penicillin without adverse reactions. 3 of these patients had immune complex-like material in their serum. It was concluded that immune complex-like material with penicilloyl specificity is not likely to contribute to the development of skin eruptions often seen in connection with penicillin treatment.},
  author       = {Ahlstedt, S and Bjursten, Lars Magnus and Hanson, L A and Lidin-Janson, G and Mobacken, H and Belin, L},
  issn         = {0020-5915},
  language     = {eng},
  number       = {2},
  pages        = {195--200},
  publisher    = {Karger},
  series       = {International Archives of Allergy and Applied Immunology},
  title        = {Evaluation of circulating immune complex-like material for development of skin reactions in connection with penicillin therapy},
  volume       = {64},
  year         = {1981},
}