Evaluation of circulating immune complex-like material for development of skin reactions in connection with penicillin therapy
(1981) In International Archives of Allergy and Applied Immunology 64(2). p.195-200- Abstract
- The levels of immune complex-like material in serum from 18 patients in connection with skin eruptions appearing during penicillin therapy were determined with a modified ELISA. Immune complex-like material could only be shown in the serum of 3 out of the 17 patients. However, according to ELISA results, the complexes appeared without the simultaneous presence of penicilloyl-specific antibodies. Neither could penicilloyl-specific antibodies be recorded in 9 patient treated with parenteral penicillin without adverse reactions. 3 of these patients had immune complex-like material in their serum. It was concluded that immune complex-like material with penicilloyl specificity is not likely to contribute to the development of skin eruptions... (More)
- The levels of immune complex-like material in serum from 18 patients in connection with skin eruptions appearing during penicillin therapy were determined with a modified ELISA. Immune complex-like material could only be shown in the serum of 3 out of the 17 patients. However, according to ELISA results, the complexes appeared without the simultaneous presence of penicilloyl-specific antibodies. Neither could penicilloyl-specific antibodies be recorded in 9 patient treated with parenteral penicillin without adverse reactions. 3 of these patients had immune complex-like material in their serum. It was concluded that immune complex-like material with penicilloyl specificity is not likely to contribute to the development of skin eruptions often seen in connection with penicillin treatment. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1102801
- author
- Ahlstedt, S ; Bjursten, Lars Magnus LU ; Hanson, L A ; Lidin-Janson, G ; Mobacken, H and Belin, L
- organization
- publishing date
- 1981
- type
- Contribution to journal
- publication status
- published
- subject
- in
- International Archives of Allergy and Applied Immunology
- volume
- 64
- issue
- 2
- pages
- 195 - 200
- publisher
- Karger
- external identifiers
-
- pmid:7461855
- scopus:0019428194
- ISSN
- 0020-5915
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Bioimplant Research (013242910)
- id
- 26c80c54-0d2f-451c-beb1-80d35580f997 (old id 1102801)
- date added to LUP
- 2016-04-01 16:27:10
- date last changed
- 2021-01-03 04:51:04
@article{26c80c54-0d2f-451c-beb1-80d35580f997, abstract = {{The levels of immune complex-like material in serum from 18 patients in connection with skin eruptions appearing during penicillin therapy were determined with a modified ELISA. Immune complex-like material could only be shown in the serum of 3 out of the 17 patients. However, according to ELISA results, the complexes appeared without the simultaneous presence of penicilloyl-specific antibodies. Neither could penicilloyl-specific antibodies be recorded in 9 patient treated with parenteral penicillin without adverse reactions. 3 of these patients had immune complex-like material in their serum. It was concluded that immune complex-like material with penicilloyl specificity is not likely to contribute to the development of skin eruptions often seen in connection with penicillin treatment.}}, author = {{Ahlstedt, S and Bjursten, Lars Magnus and Hanson, L A and Lidin-Janson, G and Mobacken, H and Belin, L}}, issn = {{0020-5915}}, language = {{eng}}, number = {{2}}, pages = {{195--200}}, publisher = {{Karger}}, series = {{International Archives of Allergy and Applied Immunology}}, title = {{Evaluation of circulating immune complex-like material for development of skin reactions in connection with penicillin therapy}}, volume = {{64}}, year = {{1981}}, }