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Mononuclear cells recovered from inflammatory synovial membrane using fine-needle biopsy

Geborek, Pierre LU ; Sandberg Wollheim, Magnhild LU and Wollheim, Frank LU (1988) In Rheumatology International 8(3). p.101-105
Abstract
A simple technique for fine-needle aspiration biopsy from the synovial membrane of arthritis knee joints preceded by lavage of the joint cavity is described. The procedure was atraumatic, well accepted, and could be performed on outpatients. Cells originating from the synovial membrane were obtained in 12 of 17 knees using a 1.2-mm cannula. The yield was 6.0 x 10(3) to 135 x 10(3) mononuclear cells. The cell populations could be expanded by stimulation with antigen and mitogen. The described fine-needle biopsy technique is of value when repeated sampling of synovial membrane cell populations is desired.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Mononuclear cells, Biopsy, Synovia, Arthritis
in
Rheumatology International
volume
8
issue
3
pages
101 - 105
publisher
Springer
external identifiers
  • pmid:3175450
  • scopus:0023919195
ISSN
1437-160X
DOI
10.1007/BF00272430
language
English
LU publication?
yes
id
5686e8b2-033a-4efb-b19f-66ef933c0709 (old id 1104266)
date added to LUP
2008-08-07 13:30:57
date last changed
2017-01-01 06:36:48
@article{5686e8b2-033a-4efb-b19f-66ef933c0709,
  abstract     = {A simple technique for fine-needle aspiration biopsy from the synovial membrane of arthritis knee joints preceded by lavage of the joint cavity is described. The procedure was atraumatic, well accepted, and could be performed on outpatients. Cells originating from the synovial membrane were obtained in 12 of 17 knees using a 1.2-mm cannula. The yield was 6.0 x 10(3) to 135 x 10(3) mononuclear cells. The cell populations could be expanded by stimulation with antigen and mitogen. The described fine-needle biopsy technique is of value when repeated sampling of synovial membrane cell populations is desired.},
  author       = {Geborek, Pierre and Sandberg Wollheim, Magnhild and Wollheim, Frank},
  issn         = {1437-160X},
  keyword      = {Mononuclear cells,Biopsy,Synovia,Arthritis},
  language     = {eng},
  number       = {3},
  pages        = {101--105},
  publisher    = {Springer},
  series       = {Rheumatology International},
  title        = {Mononuclear cells recovered from inflammatory synovial membrane using fine-needle biopsy},
  url          = {http://dx.doi.org/10.1007/BF00272430},
  volume       = {8},
  year         = {1988},
}