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Colloid cysts of the third ventricle: correlation of MR and CT findings with histology and chemical analysis

Maeder, Philippe P; Holtås, Stig LU ; Basibuyuk, L Nihal; Salford, Leif LU ; Tapper, U A Staffan and Brun, Arne LU (1990) In American Journal of Roentgenology 155(1). p.135-141
Abstract
Eight patients with colloid cysts of the third ventricle were examined with CT and MR. In six, surgical resection was performed and the material was subjected to histologic evaluation; the concentrations of trace elements were determined by particle-induced X-ray emission. Stereotaxic aspiration was performed in two. The investigation showed that colloid cysts are often iso- or hypodense relative to brain on CT (5/8), but sometimes have a center of increased density. Increased density did not correlate with increased concentration of calcium or other metals but did correlate with high cholesterol content. Colloid cysts appear more heterogeneous on MR (6/8) than on CT (3/8), despite a homogeneous appearance at histology. High signal on... (More)
Eight patients with colloid cysts of the third ventricle were examined with CT and MR. In six, surgical resection was performed and the material was subjected to histologic evaluation; the concentrations of trace elements were determined by particle-induced X-ray emission. Stereotaxic aspiration was performed in two. The investigation showed that colloid cysts are often iso- or hypodense relative to brain on CT (5/8), but sometimes have a center of increased density. Increased density did not correlate with increased concentration of calcium or other metals but did correlate with high cholesterol content. Colloid cysts appear more heterogeneous on MR (6/8) than on CT (3/8), despite a homogeneous appearance at histology. High signal on short TR/TE sequences is correlated with a high cholesterol content. A marked shortening of the T2 relaxation time is often noticed in the central part of the cyst. Analysis of trace elements showed that this phenomenon is not related to the presence of metals with paramagnetic effects. Our analysis of the contents of colloid cysts does not support the theory that differing metallic concentrations are responsible for differences in MR signal intensity or CT density. We did find that increased CT density and high MR signal correlated with high cholesterol content. (Less)
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author
organization
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type
Contribution to journal
publication status
published
subject
in
American Journal of Roentgenology
volume
155
issue
1
pages
135 - 141
publisher
American Roentgen Ray Society
external identifiers
  • pmid:2112837
ISSN
1546-3141
language
English
LU publication?
yes
id
d3fb12c2-1b40-4669-a640-bc196b8b2aaa (old id 1105244)
alternative location
http://www.ajronline.org/cgi/reprint/155/1/135
date added to LUP
2008-08-05 11:27:25
date last changed
2016-08-04 15:30:59
@article{d3fb12c2-1b40-4669-a640-bc196b8b2aaa,
  abstract     = {Eight patients with colloid cysts of the third ventricle were examined with CT and MR. In six, surgical resection was performed and the material was subjected to histologic evaluation; the concentrations of trace elements were determined by particle-induced X-ray emission. Stereotaxic aspiration was performed in two. The investigation showed that colloid cysts are often iso- or hypodense relative to brain on CT (5/8), but sometimes have a center of increased density. Increased density did not correlate with increased concentration of calcium or other metals but did correlate with high cholesterol content. Colloid cysts appear more heterogeneous on MR (6/8) than on CT (3/8), despite a homogeneous appearance at histology. High signal on short TR/TE sequences is correlated with a high cholesterol content. A marked shortening of the T2 relaxation time is often noticed in the central part of the cyst. Analysis of trace elements showed that this phenomenon is not related to the presence of metals with paramagnetic effects. Our analysis of the contents of colloid cysts does not support the theory that differing metallic concentrations are responsible for differences in MR signal intensity or CT density. We did find that increased CT density and high MR signal correlated with high cholesterol content.},
  author       = {Maeder, Philippe P and Holtås, Stig and Basibuyuk, L Nihal and Salford, Leif and Tapper, U A Staffan and Brun, Arne},
  issn         = {1546-3141},
  language     = {eng},
  number       = {1},
  pages        = {135--141},
  publisher    = {American Roentgen Ray Society},
  series       = {American Journal of Roentgenology},
  title        = {Colloid cysts of the third ventricle: correlation of MR and CT findings with histology and chemical analysis},
  volume       = {155},
  year         = {1990},
}