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Circadian variation in human cerebrospinal fluid production measured by magnetic resonance imaging

Nilsson, C; Ståhlberg, Freddy LU ; Thomsen, C; Henriksen, O; Herning, M and Owman, Christer LU (1992) In American Journal of Physiology 262(1). p.20-24
Abstract
Recent advances in magnetic resonance imaging have made it possible to visualize and quantify flow of cerebrospinal fluid (CSF) in the brain. The net flow of CSF through the cerebral aqueduct was used to measure CSF production in six normal volunteers at different times during a 24-h period. CSF production varied greatly both intra- and interindividually. The average CSF production in each time interval showed a clear tendency to circadian variation, with a minimum production 30% of maximum values (12 +/- 7 ml/h) approximately 1800 h and a nightly peak production approximately 0200 h of 42 +/- 2 ml/h. The total CSF production during the whole 24-h period, calculated as an average of all measurements, was 650 ml for the whole group and 630... (More)
Recent advances in magnetic resonance imaging have made it possible to visualize and quantify flow of cerebrospinal fluid (CSF) in the brain. The net flow of CSF through the cerebral aqueduct was used to measure CSF production in six normal volunteers at different times during a 24-h period. CSF production varied greatly both intra- and interindividually. The average CSF production in each time interval showed a clear tendency to circadian variation, with a minimum production 30% of maximum values (12 +/- 7 ml/h) approximately 1800 h and a nightly peak production approximately 0200 h of 42 +/- 2 ml/h. The total CSF production during the whole 24-h period, calculated as an average of all measurements, was 650 ml for the whole group and 630 ml for repeated measurements in each time interval in one of the volunteers. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
American Journal of Physiology
volume
262
issue
1
pages
20 - 24
publisher
American Pysiological Society
external identifiers
  • pmid:1733335
  • scopus:0026583226
ISSN
0002-9513
language
English
LU publication?
yes
id
af390186-351e-41c7-87b1-de6c38d22634 (old id 1106435)
date added to LUP
2008-08-08 14:40:15
date last changed
2017-07-16 04:05:18
@article{af390186-351e-41c7-87b1-de6c38d22634,
  abstract     = {Recent advances in magnetic resonance imaging have made it possible to visualize and quantify flow of cerebrospinal fluid (CSF) in the brain. The net flow of CSF through the cerebral aqueduct was used to measure CSF production in six normal volunteers at different times during a 24-h period. CSF production varied greatly both intra- and interindividually. The average CSF production in each time interval showed a clear tendency to circadian variation, with a minimum production 30% of maximum values (12 +/- 7 ml/h) approximately 1800 h and a nightly peak production approximately 0200 h of 42 +/- 2 ml/h. The total CSF production during the whole 24-h period, calculated as an average of all measurements, was 650 ml for the whole group and 630 ml for repeated measurements in each time interval in one of the volunteers.},
  author       = {Nilsson, C and Ståhlberg, Freddy and Thomsen, C and Henriksen, O and Herning, M and Owman, Christer},
  issn         = {0002-9513},
  language     = {eng},
  number       = {1},
  pages        = {20--24},
  publisher    = {American Pysiological Society},
  series       = {American Journal of Physiology},
  title        = {Circadian variation in human cerebrospinal fluid production measured by magnetic resonance imaging},
  volume       = {262},
  year         = {1992},
}