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Periarticular bone in rheumatoid arthritis versus arthrosis. Histomorphometry in 103 hip biopsies

Åkesson, Kristina LU ; Önsten, Ingemar LU and Obrant, Karl LU (1994) In Acta Orthopaedica Scandinavica 65(2). p.135-138
Abstract
Histomorphologic differences of the periarticular bone in rheumatoid arthritis (RA) and osteoarthrosis (OA) may be of importance for long-term prosthetic fixation. We have evaluated bone specimens, obtained during total hip replacement from an acetabular and a femoral biopsy site, in 42 RA-hips and 61 OA-hips. In both groups the bone turnover was increased in the acetabulum compared to that in the femur. In the acetabulums the total trabecular bone volume was equal, but osteoid volume, osteoid surface, resorptive surface, and the appositional rate were increased in RA. On the femoral side, only the osteoid volume was higher in RA. The increased bone turnover with a greater amount of unmineralized tissue, as well as resorptive activity in... (More)
Histomorphologic differences of the periarticular bone in rheumatoid arthritis (RA) and osteoarthrosis (OA) may be of importance for long-term prosthetic fixation. We have evaluated bone specimens, obtained during total hip replacement from an acetabular and a femoral biopsy site, in 42 RA-hips and 61 OA-hips. In both groups the bone turnover was increased in the acetabulum compared to that in the femur. In the acetabulums the total trabecular bone volume was equal, but osteoid volume, osteoid surface, resorptive surface, and the appositional rate were increased in RA. On the femoral side, only the osteoid volume was higher in RA. The increased bone turnover with a greater amount of unmineralized tissue, as well as resorptive activity in the acetabulum, may be of importance for the higher rate of acetabular component migration and loosening after total hip replacement in RA. (Less)
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Orthopaedica Scandinavica
volume
65
issue
2
pages
135 - 138
publisher
Taylor & Francis
external identifiers
  • pmid:8197843
  • scopus:0028275977
ISSN
0001-6470
DOI
10.3109/17453679408995420
language
English
LU publication?
yes
id
4fd2af85-c5f3-4466-ada7-5eeb84a2d70a (old id 1108126)
date added to LUP
2008-07-23 14:22:21
date last changed
2017-01-01 06:49:51
@article{4fd2af85-c5f3-4466-ada7-5eeb84a2d70a,
  abstract     = {Histomorphologic differences of the periarticular bone in rheumatoid arthritis (RA) and osteoarthrosis (OA) may be of importance for long-term prosthetic fixation. We have evaluated bone specimens, obtained during total hip replacement from an acetabular and a femoral biopsy site, in 42 RA-hips and 61 OA-hips. In both groups the bone turnover was increased in the acetabulum compared to that in the femur. In the acetabulums the total trabecular bone volume was equal, but osteoid volume, osteoid surface, resorptive surface, and the appositional rate were increased in RA. On the femoral side, only the osteoid volume was higher in RA. The increased bone turnover with a greater amount of unmineralized tissue, as well as resorptive activity in the acetabulum, may be of importance for the higher rate of acetabular component migration and loosening after total hip replacement in RA.},
  author       = {Åkesson, Kristina and Önsten, Ingemar and Obrant, Karl},
  issn         = {0001-6470},
  language     = {eng},
  number       = {2},
  pages        = {135--138},
  publisher    = {Taylor & Francis},
  series       = {Acta Orthopaedica Scandinavica},
  title        = {Periarticular bone in rheumatoid arthritis versus arthrosis. Histomorphometry in 103 hip biopsies},
  url          = {http://dx.doi.org/10.3109/17453679408995420},
  volume       = {65},
  year         = {1994},
}