Use of k-space segmentation in MR velocity mapping for rapid quantification of CSF flow
(1997) In Journal of Magnetic Resonance Imaging 7(6). p.972-978- Abstract
- In this work, a k-space segmentation technique for quantitative studies of pulsatile cerebrospinal fluid (CSF) flow is suggested. Three k-space lines are sampled for each of two interleaved gradient-echo sequences (velocity-compensated and velocity-encoded) within each repetition interval. Nine cardiac phases are obtained at a heart rate of 60 bpm with maintained nominal resolution and a factor of 3 in reduction of acquisition time relative to our conventional nonsegmented flow quantification protocol. Segmented and conventional sequences were compared in phantoms, in healthy volunteers, and in two patients with clinically suspected normal pressure hydrocephalus. Good agreement between flow curves obtained with the two sequences was... (More)
- In this work, a k-space segmentation technique for quantitative studies of pulsatile cerebrospinal fluid (CSF) flow is suggested. Three k-space lines are sampled for each of two interleaved gradient-echo sequences (velocity-compensated and velocity-encoded) within each repetition interval. Nine cardiac phases are obtained at a heart rate of 60 bpm with maintained nominal resolution and a factor of 3 in reduction of acquisition time relative to our conventional nonsegmented flow quantification protocol. Segmented and conventional sequences were compared in phantoms, in healthy volunteers, and in two patients with clinically suspected normal pressure hydrocephalus. Good agreement between flow curves obtained with the two sequences was demonstrated in vitro as well as in vivo. A slight underestimation of flow values in volunteers was attributed to data filtering when using the segmented sequence. Because the CSF circulation is complex and tightly connected to the vascular circulation, specific clinical applications may require flow studies at multiple positions and with different velocity encoding. In such cases, the proposed sequence can be used to gain time, but alternatively, the segmentation technique can be used to further increase spatial resolution within reasonable examination times. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1111619
- author
- Ståhlberg, Freddy LU ; Nitz, Wolfgang ; Nilsson, Christer LU and Holtås, Stig LU
- organization
- publishing date
- 1997
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- MRI, Flow, Quantification, Cerebrospinal fluid, Fast imaging
- in
- Journal of Magnetic Resonance Imaging
- volume
- 7
- issue
- 6
- pages
- 972 - 978
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- pmid:9400839
- scopus:0031397673
- ISSN
- 1522-2586
- DOI
- 10.1002/jmri.1880070607
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Department of Psychogeriatrics (013304000), Diagnostic Radiology, (Lund) (013038000)
- id
- 0b27a0d4-467f-4931-b9cc-4443d27a7fae (old id 1111619)
- date added to LUP
- 2016-04-01 12:18:51
- date last changed
- 2022-01-27 01:56:09
@article{0b27a0d4-467f-4931-b9cc-4443d27a7fae, abstract = {{In this work, a k-space segmentation technique for quantitative studies of pulsatile cerebrospinal fluid (CSF) flow is suggested. Three k-space lines are sampled for each of two interleaved gradient-echo sequences (velocity-compensated and velocity-encoded) within each repetition interval. Nine cardiac phases are obtained at a heart rate of 60 bpm with maintained nominal resolution and a factor of 3 in reduction of acquisition time relative to our conventional nonsegmented flow quantification protocol. Segmented and conventional sequences were compared in phantoms, in healthy volunteers, and in two patients with clinically suspected normal pressure hydrocephalus. Good agreement between flow curves obtained with the two sequences was demonstrated in vitro as well as in vivo. A slight underestimation of flow values in volunteers was attributed to data filtering when using the segmented sequence. Because the CSF circulation is complex and tightly connected to the vascular circulation, specific clinical applications may require flow studies at multiple positions and with different velocity encoding. In such cases, the proposed sequence can be used to gain time, but alternatively, the segmentation technique can be used to further increase spatial resolution within reasonable examination times.}}, author = {{Ståhlberg, Freddy and Nitz, Wolfgang and Nilsson, Christer and Holtås, Stig}}, issn = {{1522-2586}}, keywords = {{MRI; Flow; Quantification; Cerebrospinal fluid; Fast imaging}}, language = {{eng}}, number = {{6}}, pages = {{972--978}}, publisher = {{John Wiley & Sons Inc.}}, series = {{Journal of Magnetic Resonance Imaging}}, title = {{Use of k-space segmentation in MR velocity mapping for rapid quantification of CSF flow}}, url = {{http://dx.doi.org/10.1002/jmri.1880070607}}, doi = {{10.1002/jmri.1880070607}}, volume = {{7}}, year = {{1997}}, }