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Serum concentrations of beta-carotene and alpha-tocopherol are associated with diet, smoking, and general and central adiposity

Wallstrom, P; Wirfält, Elisabet LU ; Lahmann, P H; Gullberg, B; Janzon, L and Berglund, Göran LU (2001) In American Journal of Clinical Nutrition 73(4). p.777-785
Abstract
BACKGROUND: Previous studies of associations between diet, obesity, and blood concentrations of alpha-tocopherol and beta-carotene have been equivocal. Furthermore, most studies used only body mass index (BMI) as an obesity measure. OBJECTIVES: Our objectives were to examine the associations between energy and nutrient intakes, alcohol consumption, tobacco use, and serum cholesterol and serum concentrations of alpha-tocopherol and beta-carotene, and to examine the associations between different measures of general and central adiposity and serum concentrations of alpha-tocopherol and beta-carotene. DESIGN: This was a cross-sectional, population-based study of 253 men and 276 women aged 46-67 y. Nutrient data were collected by a modified... (More)
BACKGROUND: Previous studies of associations between diet, obesity, and blood concentrations of alpha-tocopherol and beta-carotene have been equivocal. Furthermore, most studies used only body mass index (BMI) as an obesity measure. OBJECTIVES: Our objectives were to examine the associations between energy and nutrient intakes, alcohol consumption, tobacco use, and serum cholesterol and serum concentrations of alpha-tocopherol and beta-carotene, and to examine the associations between different measures of general and central adiposity and serum concentrations of alpha-tocopherol and beta-carotene. DESIGN: This was a cross-sectional, population-based study of 253 men and 276 women aged 46-67 y. Nutrient data were collected by a modified diet history method. Measures of obesity included BMI, percentage of body fat (impedance analysis), waist-to-hip ratio, and waist circumference. The associations between serum nutrient concentrations and the other factors were examined by multiple linear regression. RESULTS: Twenty-one percent of men and 34% of women used antioxidant supplements. The mean BMI was 26.1 in men and 25.4 in women. Serum beta-carotene concentration was positively associated with serum cholesterol concentration, fiber intake, and beta-carotene intake, and negatively associated with smoking and all measures of obesity. In men, serum beta-carotene concentration was not significantly associated with central adiposity after adjustment for body fat. Serum alpha-tocopherol concentration was positively correlated with serum cholesterol, obesity, and vitamin E intake. In women, serum alpha-tocopherol concentration was also positively associated with intakes of ascorbic acid and selenium. Serum alpha-tocopherol concentration was associated with central adiposity after adjustment for body fat. CONCLUSION: Serum beta-carotene and alpha-tocopherol concentrations have different associations with diet, smoking, general adiposity, and central adiposity. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Vitamin E, ß-carotene, {alpha}-tocopherol, diet, obesity, body composition, body mass index, waist-to-hip ratio, smoking, alcohol, cross-sectional studies
in
American Journal of Clinical Nutrition
volume
73
issue
4
pages
777 - 785
publisher
American Society for Clinical Nutrition
external identifiers
  • pmid:11273853
  • scopus:0035082018
ISSN
1938-3207
language
English
LU publication?
yes
id
3d74d465-cc2e-4c52-9889-fb8ef84d198e (old id 1123067)
alternative location
http://www.ajcn.org/cgi/content/full/73/4/777
date added to LUP
2008-07-17 10:54:01
date last changed
2018-06-17 04:46:07
@article{3d74d465-cc2e-4c52-9889-fb8ef84d198e,
  abstract     = {BACKGROUND: Previous studies of associations between diet, obesity, and blood concentrations of alpha-tocopherol and beta-carotene have been equivocal. Furthermore, most studies used only body mass index (BMI) as an obesity measure. OBJECTIVES: Our objectives were to examine the associations between energy and nutrient intakes, alcohol consumption, tobacco use, and serum cholesterol and serum concentrations of alpha-tocopherol and beta-carotene, and to examine the associations between different measures of general and central adiposity and serum concentrations of alpha-tocopherol and beta-carotene. DESIGN: This was a cross-sectional, population-based study of 253 men and 276 women aged 46-67 y. Nutrient data were collected by a modified diet history method. Measures of obesity included BMI, percentage of body fat (impedance analysis), waist-to-hip ratio, and waist circumference. The associations between serum nutrient concentrations and the other factors were examined by multiple linear regression. RESULTS: Twenty-one percent of men and 34% of women used antioxidant supplements. The mean BMI was 26.1 in men and 25.4 in women. Serum beta-carotene concentration was positively associated with serum cholesterol concentration, fiber intake, and beta-carotene intake, and negatively associated with smoking and all measures of obesity. In men, serum beta-carotene concentration was not significantly associated with central adiposity after adjustment for body fat. Serum alpha-tocopherol concentration was positively correlated with serum cholesterol, obesity, and vitamin E intake. In women, serum alpha-tocopherol concentration was also positively associated with intakes of ascorbic acid and selenium. Serum alpha-tocopherol concentration was associated with central adiposity after adjustment for body fat. CONCLUSION: Serum beta-carotene and alpha-tocopherol concentrations have different associations with diet, smoking, general adiposity, and central adiposity.},
  author       = {Wallstrom, P and Wirfält, Elisabet and Lahmann, P H and Gullberg, B and Janzon, L and Berglund, Göran},
  issn         = {1938-3207},
  keyword      = {Vitamin E,ß-carotene,{alpha}-tocopherol,diet,obesity,body composition,body mass index,waist-to-hip ratio,smoking,alcohol,cross-sectional studies},
  language     = {eng},
  number       = {4},
  pages        = {777--785},
  publisher    = {American Society for Clinical Nutrition},
  series       = {American Journal of Clinical Nutrition},
  title        = {Serum concentrations of beta-carotene and alpha-tocopherol are associated with diet, smoking, and general and central adiposity},
  volume       = {73},
  year         = {2001},
}