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Behandling av osteoporotisk kotkompression. Explosionsartat intresse för vertebroplastik och kyfoplastik

Karlsson, Magnus LU ; Hasserius, Ralph LU ; Gerdhem, Paul LU ; Obrant, Karl LU and Ohlin, Acke LU (2005) In Läkartidningen 102(21). p.1644-1648
Abstract
During the last 15 years, two new treatment strategies have gained worldwide attention in the treatment of osteoporotic vertebral fractures. The exponential increase in the use of percutaneous vertebro- or kyphoplasty has up to now not been supported by scientific sound evidence-based data. There exist no prospective randomised controlled trials (RCT) that support the efficacy of the treatments, not even adequate controlled studies. Instead we have to rely on prospective and retrospective uncontrolled short-term observational studies and case-control studies. These studies consistently indicate that the short-term results after the procedures in the treatment of osteoporotic vertebral fractures are favourable, regarding both pain relief... (More)
During the last 15 years, two new treatment strategies have gained worldwide attention in the treatment of osteoporotic vertebral fractures. The exponential increase in the use of percutaneous vertebro- or kyphoplasty has up to now not been supported by scientific sound evidence-based data. There exist no prospective randomised controlled trials (RCT) that support the efficacy of the treatments, not even adequate controlled studies. Instead we have to rely on prospective and retrospective uncontrolled short-term observational studies and case-control studies. These studies consistently indicate that the short-term results after the procedures in the treatment of osteoporotic vertebral fractures are favourable, regarding both pain relief and functional status. However, if a vertebro- or a kyphoplasty produces a better outcome than conservative treatment, and if the long-term results are as favourable as the short-term results in the treatment of osteoporotic vertebral fractures, is currently unknown. (Less)
Abstract (Swedish)
Vertebroplastik och kyfoplastik är två nya behandlingsmetoder

vid osteoporotiska kotkompressioner,

där man genom en perkutant insatt kanyl fyller den

skadade kotkroppen med bencement så att frakturen

stabiliseras, ryggsmärtan reduceras och patientmobiliseringen

underlättas.

Det finns inga prospektiva, randomiserade, kontrollerade

studier publicerade som värderar effekterna

av vertebro- och kyfoplastikteknikerna.

Våra kunskaper om metodernas effekt grundas på

observationsstudier och fall–kontrollstudier, som indikerar

att vertebro- och kyfoplastik minskar patientens

ryggsmärta vid en osteoporotisk kotfraktur.

Det kliniska... (More)
Vertebroplastik och kyfoplastik är två nya behandlingsmetoder

vid osteoporotiska kotkompressioner,

där man genom en perkutant insatt kanyl fyller den

skadade kotkroppen med bencement så att frakturen

stabiliseras, ryggsmärtan reduceras och patientmobiliseringen

underlättas.

Det finns inga prospektiva, randomiserade, kontrollerade

studier publicerade som värderar effekterna

av vertebro- och kyfoplastikteknikerna.

Våra kunskaper om metodernas effekt grundas på

observationsstudier och fall–kontrollstudier, som indikerar

att vertebro- och kyfoplastik minskar patientens

ryggsmärta vid en osteoporotisk kotfraktur.

Det kliniska långtidsresultatet efter vertebro- och kyfoplastik

är dåligt utrett. (Less)
Please use this url to cite or link to this publication:
author
; ; ; and
organization
alternative title
Treatment of osteoporotic fractures - an increasing interest in vertebroplasty and kyphoplasty
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Intern frakturfixering, Kyfos, Benskörhet efter menopaus, Benskörhet, Ryggradsfrakturer
in
Läkartidningen
volume
102
issue
21
pages
1644 - 1648
publisher
Swedish Medical Association
external identifiers
  • scopus:20444388322
ISSN
0023-7205
language
Swedish
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Clinical and Molecular Osteoporosis Research Unit (013242930), Reconstructive Surgery (013240300)
id
6b8697f0-eefb-4142-bacc-994d16286b1d (old id 1132888)
alternative location
http://ltarkiv.lakartidningen.se/artNo30244
date added to LUP
2016-04-01 15:50:17
date last changed
2020-01-12 18:47:00
@article{6b8697f0-eefb-4142-bacc-994d16286b1d,
  abstract     = {During the last 15 years, two new treatment strategies have gained worldwide attention in the treatment of osteoporotic vertebral fractures. The exponential increase in the use of percutaneous vertebro- or kyphoplasty has up to now not been supported by scientific sound evidence-based data. There exist no prospective randomised controlled trials (RCT) that support the efficacy of the treatments, not even adequate controlled studies. Instead we have to rely on prospective and retrospective uncontrolled short-term observational studies and case-control studies. These studies consistently indicate that the short-term results after the procedures in the treatment of osteoporotic vertebral fractures are favourable, regarding both pain relief and functional status. However, if a vertebro- or a kyphoplasty produces a better outcome than conservative treatment, and if the long-term results are as favourable as the short-term results in the treatment of osteoporotic vertebral fractures, is currently unknown.},
  author       = {Karlsson, Magnus and Hasserius, Ralph and Gerdhem, Paul and Obrant, Karl and Ohlin, Acke},
  issn         = {0023-7205},
  language     = {swe},
  number       = {21},
  pages        = {1644--1648},
  publisher    = {Swedish Medical Association},
  series       = {Läkartidningen},
  title        = {Behandling av osteoporotisk kotkompression. Explosionsartat intresse för vertebroplastik och kyfoplastik},
  url          = {http://ltarkiv.lakartidningen.se/artNo30244},
  volume       = {102},
  year         = {2005},
}