Breastfeeding does not influence the development of inhibitors in haemophilia.
(2002) In Haemophilia 8(5). p.657-659- Abstract
- Our aim was to test the hypothesis that breastfeeding may reduce development of inhibitors in male infants with haemophilia by inducing an oral immune tolerance to factor VIII. To achieve that goal, we performed a structured epidemiological survey comprising all males born with severe haemophilia A (in all 100 patients, 19 with inhibitors) or haemophilia B (in all 16 patients, six with inhibitors) in Sweden in 1980-99. Our results show no protective effect of breastfeeding.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/114970
- author
- Knobe, Karin LU ; Tengborn, Lilian LU ; Petrini, P and Ljung, Rolf LU
- organization
- publishing date
- 2002
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Immune Tolerance, Hemophilia A: immunology, Hemophilia B: immunology, Human, Preschool, Factor VIII: metabolism, Infant, Newborn, Male, Sweden, Autoantibodies: blood, Blood Coagulation Factor Inhibitors: metabolism, Breast Feeding, Child
- in
- Haemophilia
- volume
- 8
- issue
- 5
- pages
- 657 - 659
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000177704400008
- pmid:12199675
- scopus:0036735251
- ISSN
- 1351-8216
- DOI
- 10.1046/j.1365-2516.2002.00655.x
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Paediatric Hematologic Research Group (013243020), Emergency medicine/Medicine/Surgery (013240200)
- id
- d48bca4a-3f14-4c31-95de-7ad6c67c2960 (old id 114970)
- date added to LUP
- 2016-04-01 11:49:16
- date last changed
- 2022-02-25 21:51:43
@article{d48bca4a-3f14-4c31-95de-7ad6c67c2960, abstract = {{Our aim was to test the hypothesis that breastfeeding may reduce development of inhibitors in male infants with haemophilia by inducing an oral immune tolerance to factor VIII. To achieve that goal, we performed a structured epidemiological survey comprising all males born with severe haemophilia A (in all 100 patients, 19 with inhibitors) or haemophilia B (in all 16 patients, six with inhibitors) in Sweden in 1980-99. Our results show no protective effect of breastfeeding.}}, author = {{Knobe, Karin and Tengborn, Lilian and Petrini, P and Ljung, Rolf}}, issn = {{1351-8216}}, keywords = {{Immune Tolerance; Hemophilia A: immunology; Hemophilia B: immunology; Human; Preschool; Factor VIII: metabolism; Infant; Newborn; Male; Sweden; Autoantibodies: blood; Blood Coagulation Factor Inhibitors: metabolism; Breast Feeding; Child}}, language = {{eng}}, number = {{5}}, pages = {{657--659}}, publisher = {{Wiley-Blackwell}}, series = {{Haemophilia}}, title = {{Breastfeeding does not influence the development of inhibitors in haemophilia.}}, url = {{https://lup.lub.lu.se/search/files/2656553/623789.pdf}}, doi = {{10.1046/j.1365-2516.2002.00655.x}}, volume = {{8}}, year = {{2002}}, }