von Willebrand disease update: diagnostic and treatment dilemmas
(2008) In Haemophilia 14(s3). p.56-61- Abstract
- Although von Willebrand disease (VWD) is now well-described, many facets of diagnosis and management continue to be debated. The diagnosis of type 1 disease can be difficult but recent genetic analyses help to distinguish many factors which can influence von Willebrand factor (VWF) levels and bleeding phenotype. Type 2 disease (functional abnormalities) includes a particularly interesting group of disorders with faulty binding between VWF and FVIIIC (Normandy) where treatment methods need careful consideration. Type 3 VWD is the most severe form of VWD and a new international study is underway to examine the use of prophylaxis.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1202051
- author
- Bolton-Maggs, P H B ; Lillicrap, D ; Goudemand, J and Berntorp, Erik LU
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- diagnosis, molecular genetics, prophylaxis study, VWD, VWD type 3, VWD Normandy
- in
- Haemophilia
- volume
- 14
- issue
- s3
- pages
- 56 - 61
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000256185300009
- scopus:44249103993
- ISSN
- 1351-8216
- DOI
- 10.1111/j.1365-2516.2008.01713.x
- language
- English
- LU publication?
- yes
- id
- d89ee8dd-b013-4554-bfd1-41039b5f412e (old id 1202051)
- date added to LUP
- 2016-04-01 11:47:50
- date last changed
- 2022-06-23 06:43:07
@article{d89ee8dd-b013-4554-bfd1-41039b5f412e, abstract = {{Although von Willebrand disease (VWD) is now well-described, many facets of diagnosis and management continue to be debated. The diagnosis of type 1 disease can be difficult but recent genetic analyses help to distinguish many factors which can influence von Willebrand factor (VWF) levels and bleeding phenotype. Type 2 disease (functional abnormalities) includes a particularly interesting group of disorders with faulty binding between VWF and FVIIIC (Normandy) where treatment methods need careful consideration. Type 3 VWD is the most severe form of VWD and a new international study is underway to examine the use of prophylaxis.}}, author = {{Bolton-Maggs, P H B and Lillicrap, D and Goudemand, J and Berntorp, Erik}}, issn = {{1351-8216}}, keywords = {{diagnosis; molecular genetics; prophylaxis study; VWD; VWD type 3; VWD Normandy}}, language = {{eng}}, number = {{s3}}, pages = {{56--61}}, publisher = {{Wiley-Blackwell}}, series = {{Haemophilia}}, title = {{von Willebrand disease update: diagnostic and treatment dilemmas}}, url = {{http://dx.doi.org/10.1111/j.1365-2516.2008.01713.x}}, doi = {{10.1111/j.1365-2516.2008.01713.x}}, volume = {{14}}, year = {{2008}}, }