Advanced

Intrapartum fetal ECG and diabetes

Yli, Branka M; Källén, Karin LU ; Stray-Pedersen, Babill and Amer-Wåhlin, Isis LU (2008) In Journal of Maternal-Fetal & Neonatal Medicine 21(4). p.231-238
Abstract
Aim. The objective of this study was to determine the prevalence and types of ST-segment changes of the fetal electrocardiogram (FECG) during labour in term fetuses born to mothers with diabetes mellitus (DM) or gestational diabetes. Methods. This was a retrospective case-control study involving populations from two multi centre trials: the Swedish Randomized Control Trial and the European Union ST-analysis (EU-STAN) trial. ST-segment changes were assessed in 104/309 cases and 207/468 controls from the Swedish and EU-STAN trials, respectively. Results. ST depression was present on the FECG in 22.1% of fetuses of mothers with DM compared to 12% of controls OR=2.6, 95% CI=1.4-4.7, p=0.002 after adjusting for trial, birth weight, and... (More)
Aim. The objective of this study was to determine the prevalence and types of ST-segment changes of the fetal electrocardiogram (FECG) during labour in term fetuses born to mothers with diabetes mellitus (DM) or gestational diabetes. Methods. This was a retrospective case-control study involving populations from two multi centre trials: the Swedish Randomized Control Trial and the European Union ST-analysis (EU-STAN) trial. ST-segment changes were assessed in 104/309 cases and 207/468 controls from the Swedish and EU-STAN trials, respectively. Results. ST depression was present on the FECG in 22.1% of fetuses of mothers with DM compared to 12% of controls OR=2.6, 95% CI=1.4-4.7, p=0.002 after adjusting for trial, birth weight, and nulliparity. ST elevation was present in 47.1% of DM patients and 41.2% of controls (OR=1.4, 95% CI=0.9-2.3, p=0.18). Conclusion. ST depression on the FECG was significantly more prevalent in the fetuses of mothers with DM, probably not indicating hypoxia but an altered ability of the myocardium to respond to the stress of labour. Further studies into the mechanism of fetal compromise during diabetic labour, are required. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
cardiotocography, fetal electrocardiogram, diabetes mellitus, gestational diabetes
in
Journal of Maternal-Fetal & Neonatal Medicine
volume
21
issue
4
pages
231 - 238
publisher
Taylor & Francis
external identifiers
  • wos:000255689000003
  • scopus:40549142110
ISSN
1476-7058
DOI
10.1080/14767050801924431
language
English
LU publication?
yes
id
a2f65f90-280f-4908-9ae3-b94eb1f0fff1 (old id 1204672)
date added to LUP
2008-09-17 15:04:44
date last changed
2017-02-22 10:46:30
@article{a2f65f90-280f-4908-9ae3-b94eb1f0fff1,
  abstract     = {Aim. The objective of this study was to determine the prevalence and types of ST-segment changes of the fetal electrocardiogram (FECG) during labour in term fetuses born to mothers with diabetes mellitus (DM) or gestational diabetes. Methods. This was a retrospective case-control study involving populations from two multi centre trials: the Swedish Randomized Control Trial and the European Union ST-analysis (EU-STAN) trial. ST-segment changes were assessed in 104/309 cases and 207/468 controls from the Swedish and EU-STAN trials, respectively. Results. ST depression was present on the FECG in 22.1% of fetuses of mothers with DM compared to 12% of controls OR=2.6, 95% CI=1.4-4.7, p=0.002 after adjusting for trial, birth weight, and nulliparity. ST elevation was present in 47.1% of DM patients and 41.2% of controls (OR=1.4, 95% CI=0.9-2.3, p=0.18). Conclusion. ST depression on the FECG was significantly more prevalent in the fetuses of mothers with DM, probably not indicating hypoxia but an altered ability of the myocardium to respond to the stress of labour. Further studies into the mechanism of fetal compromise during diabetic labour, are required.},
  author       = {Yli, Branka M and Källén, Karin and Stray-Pedersen, Babill and Amer-Wåhlin, Isis},
  issn         = {1476-7058},
  keyword      = {cardiotocography,fetal electrocardiogram,diabetes mellitus,gestational diabetes},
  language     = {eng},
  number       = {4},
  pages        = {231--238},
  publisher    = {Taylor & Francis},
  series       = {Journal of Maternal-Fetal & Neonatal Medicine},
  title        = {Intrapartum fetal ECG and diabetes},
  url          = {http://dx.doi.org/10.1080/14767050801924431},
  volume       = {21},
  year         = {2008},
}