Bioactive Pt(II) and Au(I) complexes based on 1,1’-bis(diphenylphosphino)metallocene derivatives
(2008) In Historielärarnas Förenings Årsskrift- Abstract
- New 1,2,1’ substituted bis(diphenylphoshino)ruthenocenes are described and used as ligands in cis-Pt(II) complexes. The new substances were also employed in Au(I) complexes, together with previously described ferrocene-based ligands. Examples of crystal structures are presented for the ligands, as well as for the platinum and gold complexes. The preliminary biological activity covering antitumour, antiviral and antimalarial properties of new gold(I) complexes were very promising.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1241933
- author
- Bjelosevic, Haris LU ; Guzei, Ilia A. ; Spencer, Lara C. ; Darkwa, James ; Persson, Tina LU and Elmroth, Sofi LU
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- unpublished
- subject
- keywords
- bioactive, anticancer, metallocenes, gold, platinum, antiviral
- in
- Historielärarnas Förenings Årsskrift
- publisher
- Historielärarnas förening
- ISSN
- 0439-2434
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Biochemistry and Structural Biology (S) (000006142), Organic chemistry (S/LTH) (011001240)
- id
- 5923957f-9441-42ad-8609-30e72d93ff25 (old id 1241933)
- date added to LUP
- 2016-04-04 12:58:52
- date last changed
- 2019-11-25 09:03:47
@article{5923957f-9441-42ad-8609-30e72d93ff25, abstract = {{New 1,2,1’ substituted bis(diphenylphoshino)ruthenocenes are described and used as ligands in cis-Pt(II) complexes. The new substances were also employed in Au(I) complexes, together with previously described ferrocene-based ligands. Examples of crystal structures are presented for the ligands, as well as for the platinum and gold complexes. The preliminary biological activity covering antitumour, antiviral and antimalarial properties of new gold(I) complexes were very promising.}}, author = {{Bjelosevic, Haris and Guzei, Ilia A. and Spencer, Lara C. and Darkwa, James and Persson, Tina and Elmroth, Sofi}}, issn = {{0439-2434}}, keywords = {{bioactive; anticancer; metallocenes; gold; platinum; antiviral}}, language = {{eng}}, publisher = {{Historielärarnas förening}}, series = {{Historielärarnas Förenings Årsskrift}}, title = {{Bioactive Pt(II) and Au(I) complexes based on 1,1’-bis(diphenylphosphino)metallocene derivatives}}, url = {{https://lup.lub.lu.se/search/files/6031050/1241935.pdf}}, year = {{2008}}, }