Histopathological examinations of rat brains after long-term exposure to GSM-900 mobile phone radiation.
Grafström, Gustav LU ; Nittby, Henrietta LU ; Brun, Arne LU ; Malmgren, Lars LU ; Persson, Bertil R LU
; Salford, Leif
LU
and Eberhardt, Jacob
LU
(2008)
In Brain Research Bulletin
77.
p.257-263
- Abstract
- In order to mimic the real life situation, with often life-long exposure to the electromagnetic fields emitted by mobile phones, we have investigated in a rat model the effects of repeated exposures under a long period to Global System for Mobile Communication-900MHz (GSM-900) radiation. Out of a total of 56 rats, 32 were exposed once weekly in a 2-h period, for totally 55 weeks, at different average whole-body specific absorption rates (SAR) (of in average 0.6 and 60mW/kg at the initiation of the experimental period). The animals were exposed in a transverse electromagnetic transmission line chamber (TEM-cell) to radiation emitted by a GSM-900 test phone. Sixteen animals were sham exposed and eight animals were cage controls, which never... (More)
- In order to mimic the real life situation, with often life-long exposure to the electromagnetic fields emitted by mobile phones, we have investigated in a rat model the effects of repeated exposures under a long period to Global System for Mobile Communication-900MHz (GSM-900) radiation. Out of a total of 56 rats, 32 were exposed once weekly in a 2-h period, for totally 55 weeks, at different average whole-body specific absorption rates (SAR) (of in average 0.6 and 60mW/kg at the initiation of the experimental period). The animals were exposed in a transverse electromagnetic transmission line chamber (TEM-cell) to radiation emitted by a GSM-900 test phone. Sixteen animals were sham exposed and eight animals were cage controls, which never left the animal house. After behavioural tests, 5-7 weeks after the last exposure, the brains were evaluated for histopathological alterations such as albumin extravasation, dark neurons, lipofuscin aggregation and signs of cytoskeletal and neuritic neuronal changes of the type seen in human ageing. In this study, no significant alteration of any these histopathological parameters was found, when comparing the GSM exposed animals to the sham exposed controls. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1243196
- author
- Grafström, Gustav
LU
; Nittby, Henrietta
LU
; Brun, Arne
LU
; Malmgren, Lars
LU
; Persson, Bertil R
LU
; Salford, Leif
LU
and Eberhardt, Jacob
LU
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Brain Research Bulletin
- volume
- 77
- pages
- 257 - 263
- publisher
- Elsevier
- external identifiers
-
- wos:000261126400008
- pmid:18782606
- scopus:54549115167
- pmid:18782606
- ISSN
- 0361-9230
- DOI
- 10.1016/j.brainresbull.2008.08.004
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Radiation Physics, Lund (013034000), Clinic of Neurosurgery: University Hospital, Lund (LUR000009), Max-laboratory (011012005), Division V (013230900), Department of Clinical Sciences, Lund (013230000)
- id
- ffc79cb6-d31e-494a-bc36-8a9592cb5afa (old id 1243196)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/18782606?dopt=Abstract
- date added to LUP
- 2016-04-04 08:47:44
- date last changed
- 2022-03-15 08:45:50
@article{ffc79cb6-d31e-494a-bc36-8a9592cb5afa,
abstract = {{In order to mimic the real life situation, with often life-long exposure to the electromagnetic fields emitted by mobile phones, we have investigated in a rat model the effects of repeated exposures under a long period to Global System for Mobile Communication-900MHz (GSM-900) radiation. Out of a total of 56 rats, 32 were exposed once weekly in a 2-h period, for totally 55 weeks, at different average whole-body specific absorption rates (SAR) (of in average 0.6 and 60mW/kg at the initiation of the experimental period). The animals were exposed in a transverse electromagnetic transmission line chamber (TEM-cell) to radiation emitted by a GSM-900 test phone. Sixteen animals were sham exposed and eight animals were cage controls, which never left the animal house. After behavioural tests, 5-7 weeks after the last exposure, the brains were evaluated for histopathological alterations such as albumin extravasation, dark neurons, lipofuscin aggregation and signs of cytoskeletal and neuritic neuronal changes of the type seen in human ageing. In this study, no significant alteration of any these histopathological parameters was found, when comparing the GSM exposed animals to the sham exposed controls.}},
author = {{Grafström, Gustav and Nittby, Henrietta and Brun, Arne and Malmgren, Lars and Persson, Bertil R and Salford, Leif and Eberhardt, Jacob}},
issn = {{0361-9230}},
language = {{eng}},
pages = {{257--263}},
publisher = {{Elsevier}},
series = {{Brain Research Bulletin}},
title = {{Histopathological examinations of rat brains after long-term exposure to GSM-900 mobile phone radiation.}},
url = {{https://lup.lub.lu.se/search/files/5197164/1273385.pdf}},
doi = {{10.1016/j.brainresbull.2008.08.004}},
volume = {{77}},
year = {{2008}},
}