High maternal body mass index increases the risk of neonatal early onset group B streptococcal disease
(2008) In Acta Pædiatrica 97(10). p.1386-1389- Abstract
- Objective: The aim of this study was to analyse the occurrence of neonatal early onset group B streptococcal (EOGBS) disease relative to maternal body mass index (BMI). Method: A cohort of Swedish parturients with an early pregnancy BMI registered was investigated. Data were retrieved from population-based registers during 1997-2001, (n = 344 127, elective caesarean section excluded). Medical records of all infants with a diagnosis of EOGBS septicaemia (P36.0) were scrutinized for verification of the diagnosis. There were 136 cases with blood culture-positive septicaemia and 112 cases with clinical infection. Odds ratios (OR) and 95% confidence intervals (CI) were calculated using multiple logistic regression. Results: In obese parturients... (More)
- Objective: The aim of this study was to analyse the occurrence of neonatal early onset group B streptococcal (EOGBS) disease relative to maternal body mass index (BMI). Method: A cohort of Swedish parturients with an early pregnancy BMI registered was investigated. Data were retrieved from population-based registers during 1997-2001, (n = 344 127, elective caesarean section excluded). Medical records of all infants with a diagnosis of EOGBS septicaemia (P36.0) were scrutinized for verification of the diagnosis. There were 136 cases with blood culture-positive septicaemia and 112 cases with clinical infection. Odds ratios (OR) and 95% confidence intervals (CI) were calculated using multiple logistic regression. Results: In obese parturients with BMI > 30, there was an 80% increased risk for verified neonatal EOGBS disease (OR 1.8, 95% CI 1.1-3.0). When cases with clinical sepsis were included a significant risk increment was also found in overweight women with BMI 25.0-29.9 (OR 1.5, 95% CI 1.1-2.0). Conclusion: Maternal obesity and overweight are risk factors associated with increased risk of neonatal EOGBS disease. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1247139
- author
- Hakansson, Stellan and Källén, Karin LU
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- obesity, newborn, group B streptococcus, body mass index, septicaemia, early onset
- in
- Acta Pædiatrica
- volume
- 97
- issue
- 10
- pages
- 1386 - 1389
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000259146200017
- scopus:51349163603
- pmid:18647277
- ISSN
- 1651-2227
- DOI
- 10.1111/j.1651-2227.2008.00940.x
- language
- English
- LU publication?
- yes
- id
- a636500a-9712-4f47-ba04-d83ee8df4d0d (old id 1247139)
- date added to LUP
- 2016-04-01 13:54:45
- date last changed
- 2022-01-27 21:49:18
@article{a636500a-9712-4f47-ba04-d83ee8df4d0d,
abstract = {{Objective: The aim of this study was to analyse the occurrence of neonatal early onset group B streptococcal (EOGBS) disease relative to maternal body mass index (BMI). Method: A cohort of Swedish parturients with an early pregnancy BMI registered was investigated. Data were retrieved from population-based registers during 1997-2001, (n = 344 127, elective caesarean section excluded). Medical records of all infants with a diagnosis of EOGBS septicaemia (P36.0) were scrutinized for verification of the diagnosis. There were 136 cases with blood culture-positive septicaemia and 112 cases with clinical infection. Odds ratios (OR) and 95% confidence intervals (CI) were calculated using multiple logistic regression. Results: In obese parturients with BMI > 30, there was an 80% increased risk for verified neonatal EOGBS disease (OR 1.8, 95% CI 1.1-3.0). When cases with clinical sepsis were included a significant risk increment was also found in overweight women with BMI 25.0-29.9 (OR 1.5, 95% CI 1.1-2.0). Conclusion: Maternal obesity and overweight are risk factors associated with increased risk of neonatal EOGBS disease.}},
author = {{Hakansson, Stellan and Källén, Karin}},
issn = {{1651-2227}},
keywords = {{obesity; newborn; group B streptococcus; body mass index; septicaemia; early onset}},
language = {{eng}},
number = {{10}},
pages = {{1386--1389}},
publisher = {{Wiley-Blackwell}},
series = {{Acta Pædiatrica}},
title = {{High maternal body mass index increases the risk of neonatal early onset group B streptococcal disease}},
url = {{http://dx.doi.org/10.1111/j.1651-2227.2008.00940.x}},
doi = {{10.1111/j.1651-2227.2008.00940.x}},
volume = {{97}},
year = {{2008}},
}