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The quality of reporting and outcome measures in randomized clinical trials related to upper-extremity disorders.

Gummesson, Christina LU ; Atroshi, Isam and Ekdahl, Charlotte LU (2004) In Journal of Hand Surgery 29(4). p.727-734
Abstract
Purpose



Randomized clinical trials can provide strong evidence regarding effective treatment options. The quality of reporting and the type of outcome measures used are important when judging whether results justify change in clinical practice. The aim of this study was to assess the quality of reporting of randomized clinical trials related to treatment of upper-extremity disorders, published in 4 hand surgical and orthopedic journals during an 11-year period, and assess the type of outcome measures used in the trials.



Methods



Eligible articles were identified by reviewing all abstracts published in the 4 journals from 1992 through 2002. The quality of reporting was assessed by a... (More)
Purpose



Randomized clinical trials can provide strong evidence regarding effective treatment options. The quality of reporting and the type of outcome measures used are important when judging whether results justify change in clinical practice. The aim of this study was to assess the quality of reporting of randomized clinical trials related to treatment of upper-extremity disorders, published in 4 hand surgical and orthopedic journals during an 11-year period, and assess the type of outcome measures used in the trials.



Methods



Eligible articles were identified by reviewing all abstracts published in the 4 journals from 1992 through 2002. The quality of reporting was assessed by a modified Jadad scale that consisted of 3 items (randomization, blinding, and withdrawals/dropouts). A higher score (0–5) indicated higher quality. The outcome measures were classified according to the International Classification of Functioning, Disability and Health into the levels of body function and structure, activity, and participation.



Results



Of 92 articles reporting randomized clinical trials, 40 articles described appropriate randomization method that implied they were truly randomized studies, 31 articles did not describe the randomization method, and 21 articles (23%) described inappropriate randomization methods. Double or single blinding was reported in 33 articles. Absence or description of withdrawals/dropouts was shown in 77 articles. The median quality score calculated for all 92 articles was 2 (range, 0–5) points. The median score for the 28 articles published 1992 through 1996 was 1 (range, 0–5) points and for the 64 articles published from 1997 through 2002 was 3 (range, 0–5) points. All trials used outcome measures on body function and structure level; 41% used measures of activity and/or participation.



Conclusions



There is a need to improve the quality of reporting of upper-extremity randomized clinical trials and to increase the use of outcome measures covering different aspects of disability. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
outcome measures, Clinical trials, Jadad scale, upper extremity, randomized
in
Journal of Hand Surgery
volume
29
issue
4
pages
727 - 734
publisher
Elsevier
external identifiers
  • pmid:15249101
  • wos:000222812100027
  • scopus:3142684492
ISSN
1531-6564
DOI
10.1016/j.jhsa.2004.04.003
language
English
LU publication?
yes
id
09c28701-f3f2-4fe0-837d-2499b86160e0 (old id 125864)
date added to LUP
2007-07-24 09:54:14
date last changed
2017-08-27 05:10:33
@article{09c28701-f3f2-4fe0-837d-2499b86160e0,
  abstract     = {Purpose<br/><br>
<br/><br>
Randomized clinical trials can provide strong evidence regarding effective treatment options. The quality of reporting and the type of outcome measures used are important when judging whether results justify change in clinical practice. The aim of this study was to assess the quality of reporting of randomized clinical trials related to treatment of upper-extremity disorders, published in 4 hand surgical and orthopedic journals during an 11-year period, and assess the type of outcome measures used in the trials.<br/><br>
<br/><br>
Methods<br/><br>
<br/><br>
Eligible articles were identified by reviewing all abstracts published in the 4 journals from 1992 through 2002. The quality of reporting was assessed by a modified Jadad scale that consisted of 3 items (randomization, blinding, and withdrawals/dropouts). A higher score (0–5) indicated higher quality. The outcome measures were classified according to the International Classification of Functioning, Disability and Health into the levels of body function and structure, activity, and participation.<br/><br>
<br/><br>
Results<br/><br>
<br/><br>
Of 92 articles reporting randomized clinical trials, 40 articles described appropriate randomization method that implied they were truly randomized studies, 31 articles did not describe the randomization method, and 21 articles (23%) described inappropriate randomization methods. Double or single blinding was reported in 33 articles. Absence or description of withdrawals/dropouts was shown in 77 articles. The median quality score calculated for all 92 articles was 2 (range, 0–5) points. The median score for the 28 articles published 1992 through 1996 was 1 (range, 0–5) points and for the 64 articles published from 1997 through 2002 was 3 (range, 0–5) points. All trials used outcome measures on body function and structure level; 41% used measures of activity and/or participation.<br/><br>
<br/><br>
Conclusions<br/><br>
<br/><br>
There is a need to improve the quality of reporting of upper-extremity randomized clinical trials and to increase the use of outcome measures covering different aspects of disability.},
  author       = {Gummesson, Christina and Atroshi, Isam and Ekdahl, Charlotte},
  issn         = {1531-6564},
  keyword      = {outcome measures,Clinical trials,Jadad scale,upper extremity,randomized},
  language     = {eng},
  number       = {4},
  pages        = {727--734},
  publisher    = {Elsevier},
  series       = {Journal of Hand Surgery},
  title        = {The quality of reporting and outcome measures in randomized clinical trials related to upper-extremity disorders.},
  url          = {http://dx.doi.org/10.1016/j.jhsa.2004.04.003},
  volume       = {29},
  year         = {2004},
}