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Quality assurance of patient dosimetry in boron neutron capture therapy

Munck af Rosenschöld, Per LU orcid ; Capala, Jacek ; Ceberg, Crister LU orcid ; Giusti, Valerio ; Salford, Leif LU and Persson, Bertil R LU orcid (2004) In Acta Oncologica 43(4). p.404-411
Abstract

The verification of the correctness of planned and executed treatments is imperative for safety in radiotherapy. The purpose of the present work is to describe and evaluate the quality assurance (QA) procedures for patient dosimetry implemented at the boron neutron capture therapy (BNCT) facility at Studsvik, Sweden. The dosimetric complexity of the mixed neutron-photon field during BNCT suggests a careful verification of routine procedures, specifically the treatment planning calculations. In the present study, two methods for QA of patient dosimetry are presented. The first is executed prior to radiotherapy and involves an independent check of the planned absorbed dose to be delivered to a point in the patient for each treatment... (More)

The verification of the correctness of planned and executed treatments is imperative for safety in radiotherapy. The purpose of the present work is to describe and evaluate the quality assurance (QA) procedures for patient dosimetry implemented at the boron neutron capture therapy (BNCT) facility at Studsvik, Sweden. The dosimetric complexity of the mixed neutron-photon field during BNCT suggests a careful verification of routine procedures, specifically the treatment planning calculations. In the present study, two methods for QA of patient dosimetry are presented. The first is executed prior to radiotherapy and involves an independent check of the planned absorbed dose to be delivered to a point in the patient for each treatment field. The second QA procedure involves in vivo dosimetry measurements using posttreatment activation analysis. Absorbed dose conversion factors taking the difference in material composition and geometry of the patient and the PMMA phantom used for reference dosimetry were determined using the Monte Carlo method. The agreement of the QA procedure prior to radiotherapy reveals an acceptably small deviation for 60 treatment fields of ±4.2% (1 SD), while the in vivo dosimetry method presented may benefit from improvements, as the deviations observed were quite substantial (±12%, 1 SD), and were unlikely to be due to actual errors in the clinical dosimetry.

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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Sensitivity and Specificity, Support, Boron Neutron Capture Therapy: methods, Non-U.S. Gov't, Human, Monte Carlo Method, Radiotherapy Dosage, Radiotherapy Planning, Radiation, Radiation Monitoring, Imaging, Radiation Injuries: prevention & control, Quality Control, Computer-Assisted, Phantoms, Comparative Study, Brain Neoplasms: radiotherapy, Dose-Response Relationship
in
Acta Oncologica
volume
43
issue
4
pages
404 - 411
publisher
Taylor & Francis
external identifiers
  • wos:000221860800006
  • pmid:15303503
  • scopus:3042714495
  • pmid:15303503
ISSN
1651-226X
DOI
10.1080/02841860410031390
language
English
LU publication?
yes
id
0cbf3e94-bf11-4168-b32e-ebb082cf573a (old id 126786)
date added to LUP
2016-04-01 16:58:32
date last changed
2023-07-20 09:28:01
@article{0cbf3e94-bf11-4168-b32e-ebb082cf573a,
  abstract     = {{<p>The verification of the correctness of planned and executed treatments is imperative for safety in radiotherapy. The purpose of the present work is to describe and evaluate the quality assurance (QA) procedures for patient dosimetry implemented at the boron neutron capture therapy (BNCT) facility at Studsvik, Sweden. The dosimetric complexity of the mixed neutron-photon field during BNCT suggests a careful verification of routine procedures, specifically the treatment planning calculations. In the present study, two methods for QA of patient dosimetry are presented. The first is executed prior to radiotherapy and involves an independent check of the planned absorbed dose to be delivered to a point in the patient for each treatment field. The second QA procedure involves in vivo dosimetry measurements using posttreatment activation analysis. Absorbed dose conversion factors taking the difference in material composition and geometry of the patient and the PMMA phantom used for reference dosimetry were determined using the Monte Carlo method. The agreement of the QA procedure prior to radiotherapy reveals an acceptably small deviation for 60 treatment fields of ±4.2% (1 SD), while the in vivo dosimetry method presented may benefit from improvements, as the deviations observed were quite substantial (±12%, 1 SD), and were unlikely to be due to actual errors in the clinical dosimetry.</p>}},
  author       = {{Munck af Rosenschöld, Per and Capala, Jacek and Ceberg, Crister and Giusti, Valerio and Salford, Leif and Persson, Bertil R}},
  issn         = {{1651-226X}},
  keywords     = {{Sensitivity and Specificity; Support; Boron Neutron Capture Therapy: methods; Non-U.S. Gov't; Human; Monte Carlo Method; Radiotherapy Dosage; Radiotherapy Planning; Radiation; Radiation Monitoring; Imaging; Radiation Injuries: prevention & control; Quality Control; Computer-Assisted; Phantoms; Comparative Study; Brain Neoplasms: radiotherapy; Dose-Response Relationship}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{404--411}},
  publisher    = {{Taylor & Francis}},
  series       = {{Acta Oncologica}},
  title        = {{Quality assurance of patient dosimetry in boron neutron capture therapy}},
  url          = {{http://dx.doi.org/10.1080/02841860410031390}},
  doi          = {{10.1080/02841860410031390}},
  volume       = {{43}},
  year         = {{2004}},
}