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Streptomyces morphogenetics: dissecting differentiation in a filamentous bacterium.

Flärdh, Klas LU and Buttner, Mark J (2009) In Nature Reviews. Microbiology 7(1). p.36-49
Abstract
During the life cycle of the filamentous bacteria Streptomyces, morphological differentiation is closely integrated with fundamental growth and cell-cycle processes, as well as with truly complex multicellular behaviour that involves hormone-like extracellular signalling and coordination with an extraordinarily diverse secondary metabolism. Not only are the bacterial cytoskeleton and the machineries for cell-wall assembly, cell division and chromosome segregation reorganized during sporulation, but the developmental programme of these fascinating organisms also has many unusual elements, including the formation of a sporulating aerial mycelium and the production of a surfactant peptide and a hydrophobic sheath that allow cells to escape... (More)
During the life cycle of the filamentous bacteria Streptomyces, morphological differentiation is closely integrated with fundamental growth and cell-cycle processes, as well as with truly complex multicellular behaviour that involves hormone-like extracellular signalling and coordination with an extraordinarily diverse secondary metabolism. Not only are the bacterial cytoskeleton and the machineries for cell-wall assembly, cell division and chromosome segregation reorganized during sporulation, but the developmental programme of these fascinating organisms also has many unusual elements, including the formation of a sporulating aerial mycelium and the production of a surfactant peptide and a hydrophobic sheath that allow cells to escape from the surface tension of the growth medium. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Streptomyces: cytology, Streptomyces: physiology
in
Nature Reviews. Microbiology
volume
7
issue
1
pages
36 - 49
publisher
Nature Publishing Group
external identifiers
  • wos:000262110300011
  • scopus:55549086417
ISSN
1740-1534
DOI
10.1038/nrmicro1968
language
English
LU publication?
yes
id
dba98d2b-8968-4912-aa23-e55def992d0d (old id 1276197)
date added to LUP
2009-01-21 12:29:39
date last changed
2017-12-10 04:00:20
@article{dba98d2b-8968-4912-aa23-e55def992d0d,
  abstract     = {During the life cycle of the filamentous bacteria Streptomyces, morphological differentiation is closely integrated with fundamental growth and cell-cycle processes, as well as with truly complex multicellular behaviour that involves hormone-like extracellular signalling and coordination with an extraordinarily diverse secondary metabolism. Not only are the bacterial cytoskeleton and the machineries for cell-wall assembly, cell division and chromosome segregation reorganized during sporulation, but the developmental programme of these fascinating organisms also has many unusual elements, including the formation of a sporulating aerial mycelium and the production of a surfactant peptide and a hydrophobic sheath that allow cells to escape from the surface tension of the growth medium.},
  author       = {Flärdh, Klas and Buttner, Mark J},
  issn         = {1740-1534},
  keyword      = {Streptomyces: cytology,Streptomyces: physiology},
  language     = {eng},
  number       = {1},
  pages        = {36--49},
  publisher    = {Nature Publishing Group},
  series       = {Nature Reviews. Microbiology},
  title        = {Streptomyces morphogenetics: dissecting differentiation in a filamentous bacterium.},
  url          = {http://dx.doi.org/10.1038/nrmicro1968},
  volume       = {7},
  year         = {2009},
}