Autofluorescence insensitive imaging using upconverting nanocrystals in scattering media
(2008) In Applied Physics Letters 93(17).- Abstract
- Autofluorescence is a nuisance in the field of fluorescence imaging and tomography of exogenous molecular markers in tissue, degrading the quality of the collected data. In this letter, we report autofluorescence insensitive imaging using highly efficient upconverting nanocrystals (NaYF4: Yb3+ /Tm3+) in a tissue phantom illuminated with near- infrared radiation of 85 mW/cm(2). It was found that imaging with such nanocrystals leads to an exceptionally high contrast compared to traditional downconverting fluorophores due to the absence of autofluorescence. Upconverting nanocrystals may be envisaged as important biological markers for tissue imaging purposes. c 2008 American Institute of Physics. [DOI: 10.1063/1.3005588]
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1283683
- author
- Xu, Can LU ; Svensson, Niclas ; Axelsson, Johan LU ; Svenmarker, Pontus LU ; Somesfalean, Gabriel LU ; Chen, Guanying ; Liang, Huijuan ; Liu, Haichun ; Zhang, Zhiguo and Andersson-Engels, Stefan LU
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Applied Physics Letters
- volume
- 93
- issue
- 17
- publisher
- American Institute of Physics (AIP)
- external identifiers
-
- wos:000260571800003
- scopus:55149103100
- ISSN
- 0003-6951
- DOI
- 10.1063/1.3005588
- language
- English
- LU publication?
- yes
- id
- 8154a135-dd78-48ef-94be-855b7d48161f (old id 1283683)
- date added to LUP
- 2016-04-01 11:37:10
- date last changed
- 2022-03-05 03:51:49
@article{8154a135-dd78-48ef-94be-855b7d48161f, abstract = {{Autofluorescence is a nuisance in the field of fluorescence imaging and tomography of exogenous molecular markers in tissue, degrading the quality of the collected data. In this letter, we report autofluorescence insensitive imaging using highly efficient upconverting nanocrystals (NaYF4: Yb3+ /Tm3+) in a tissue phantom illuminated with near- infrared radiation of 85 mW/cm(2). It was found that imaging with such nanocrystals leads to an exceptionally high contrast compared to traditional downconverting fluorophores due to the absence of autofluorescence. Upconverting nanocrystals may be envisaged as important biological markers for tissue imaging purposes. c 2008 American Institute of Physics. [DOI: 10.1063/1.3005588]}}, author = {{Xu, Can and Svensson, Niclas and Axelsson, Johan and Svenmarker, Pontus and Somesfalean, Gabriel and Chen, Guanying and Liang, Huijuan and Liu, Haichun and Zhang, Zhiguo and Andersson-Engels, Stefan}}, issn = {{0003-6951}}, language = {{eng}}, number = {{17}}, publisher = {{American Institute of Physics (AIP)}}, series = {{Applied Physics Letters}}, title = {{Autofluorescence insensitive imaging using upconverting nanocrystals in scattering media}}, url = {{https://lup.lub.lu.se/search/files/2563455/1514551.pdf}}, doi = {{10.1063/1.3005588}}, volume = {{93}}, year = {{2008}}, }