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The Neuroanatomic Localization of Epstein-Barr Virus Encephalitis May Be a Predictive Factor for Its Clinical Outcome: A Case Report and Review of 100 Cases in 28 Reports.

Abul-Kasim, Kasim LU ; Palm, Lars LU ; Maly, Pavel LU and Sundgren, Pia LU (2009) In Journal of Child Neurology 24. p.720-726
Abstract
Encephalitis is one of the manifestations of infection with Epstein-Barr virus with clinical outcome varying from complete recovery to death. A 16-year-old boy with Epstein-Barr virus encephalitis with global cortical and subcortical gray matter involvement and a full clinical recovery is reported. The case inspired a literature review which yielded 100 cases of Epstein-Barr virus encephalitis subjected to radiological investigation and published in 28 reports. Cerebellum and basal ganglia were reported to be equally involved by Epstein-Barr virus infection, next to cerebral hemisphere. Patients with isolated hemispheric gray or white matter involvement were reported to achieve good recovery while almost half of the patients with thalamic... (More)
Encephalitis is one of the manifestations of infection with Epstein-Barr virus with clinical outcome varying from complete recovery to death. A 16-year-old boy with Epstein-Barr virus encephalitis with global cortical and subcortical gray matter involvement and a full clinical recovery is reported. The case inspired a literature review which yielded 100 cases of Epstein-Barr virus encephalitis subjected to radiological investigation and published in 28 reports. Cerebellum and basal ganglia were reported to be equally involved by Epstein-Barr virus infection, next to cerebral hemisphere. Patients with isolated hemispheric gray or white matter involvement were reported to achieve good recovery while almost half of the patients with thalamic involvement developed sequelae. The highest mortality rate was among patients with isolated brain stem involvement. In conclusion, neuroanatomic distribution of the radiological abnormalities in Epstein-Barr virus encephalitis may be useful as a prognostic marker. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Child Neurology
volume
24
pages
720 - 726
publisher
SAGE Publications Inc.
external identifiers
  • wos:000266124900011
  • pmid:19151367
  • scopus:66849121695
ISSN
1708-8283
DOI
10.1177/0883073808327842
language
English
LU publication?
yes
id
9f2d6127-1c71-46b8-87d9-bd8c9b0ef7be (old id 1289598)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19151367?dopt=Abstract
date added to LUP
2009-02-04 11:15:31
date last changed
2017-03-12 04:24:11
@article{9f2d6127-1c71-46b8-87d9-bd8c9b0ef7be,
  abstract     = {Encephalitis is one of the manifestations of infection with Epstein-Barr virus with clinical outcome varying from complete recovery to death. A 16-year-old boy with Epstein-Barr virus encephalitis with global cortical and subcortical gray matter involvement and a full clinical recovery is reported. The case inspired a literature review which yielded 100 cases of Epstein-Barr virus encephalitis subjected to radiological investigation and published in 28 reports. Cerebellum and basal ganglia were reported to be equally involved by Epstein-Barr virus infection, next to cerebral hemisphere. Patients with isolated hemispheric gray or white matter involvement were reported to achieve good recovery while almost half of the patients with thalamic involvement developed sequelae. The highest mortality rate was among patients with isolated brain stem involvement. In conclusion, neuroanatomic distribution of the radiological abnormalities in Epstein-Barr virus encephalitis may be useful as a prognostic marker.},
  author       = {Abul-Kasim, Kasim and Palm, Lars and Maly, Pavel and Sundgren, Pia},
  issn         = {1708-8283},
  language     = {eng},
  pages        = {720--726},
  publisher    = {SAGE Publications Inc.},
  series       = {Journal of Child Neurology},
  title        = {The Neuroanatomic Localization of Epstein-Barr Virus Encephalitis May Be a Predictive Factor for Its Clinical Outcome: A Case Report and Review of 100 Cases in 28 Reports.},
  url          = {http://dx.doi.org/10.1177/0883073808327842},
  volume       = {24},
  year         = {2009},
}