Non-alcoholic Steatohepatitis Induces a Decrease in the Levels of S-100b in the Rat Brain
(2008) In Neurophysiology 40(4). p.316-318- Abstract
- Using an experimental model of non-alcoholic (alimentary-induced) steatohepatitis in rats, we found that this pathological condition created by consumption of a special diet for 16 weeks results in a drop in the brain mass (by 22%, on average) and also in decreases in the size and morphological modifications of astrocytes and the level of a calcium-binding protein, S-100b. The latter shifts were greater in the hindbrain, including the cerebellum (34.8%), than in the hemispheres, including the thalamus, hypothalamus, hippocampus, and cortex (18.0%).
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1375221
- author
- Ushakova, G. A. ; Fomenko, O. Z. and Pierzynowski, Stefan LU
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- encephalopathy, hepatic, non-alcoholic steatohepatitis, S-100b, astrocytes
- in
- Neurophysiology
- volume
- 40
- issue
- 4
- pages
- 316 - 318
- publisher
- Springer
- external identifiers
-
- wos:000263425200012
- scopus:60649114645
- ISSN
- 0090-2977
- DOI
- 10.1007/s11062-009-9051-x
- language
- English
- LU publication?
- yes
- id
- 0c41f437-afd8-4b31-9bb4-491454c08393 (old id 1375221)
- date added to LUP
- 2016-04-01 15:02:15
- date last changed
- 2022-01-28 03:48:35
@article{0c41f437-afd8-4b31-9bb4-491454c08393, abstract = {{Using an experimental model of non-alcoholic (alimentary-induced) steatohepatitis in rats, we found that this pathological condition created by consumption of a special diet for 16 weeks results in a drop in the brain mass (by 22%, on average) and also in decreases in the size and morphological modifications of astrocytes and the level of a calcium-binding protein, S-100b. The latter shifts were greater in the hindbrain, including the cerebellum (34.8%), than in the hemispheres, including the thalamus, hypothalamus, hippocampus, and cortex (18.0%).}}, author = {{Ushakova, G. A. and Fomenko, O. Z. and Pierzynowski, Stefan}}, issn = {{0090-2977}}, keywords = {{encephalopathy; hepatic; non-alcoholic steatohepatitis; S-100b; astrocytes}}, language = {{eng}}, number = {{4}}, pages = {{316--318}}, publisher = {{Springer}}, series = {{Neurophysiology}}, title = {{Non-alcoholic Steatohepatitis Induces a Decrease in the Levels of S-100b in the Rat Brain}}, url = {{http://dx.doi.org/10.1007/s11062-009-9051-x}}, doi = {{10.1007/s11062-009-9051-x}}, volume = {{40}}, year = {{2008}}, }