Does an active sun exposure habit lower the risk of venous thrombotic events? A D-lightful hypothesis
Lindqvist, P. G. ; Epstein, Elisabeth LU and Olsson, Håkan LU
(2009)
In Journal of Thrombosis and Haemostasis
7(4).
p.605-610
- Abstract
- Background: Venous and arterial thrombotic complications exhibit a seasonal variation, with risk peaking in winter and dropping to a nadir in summer. We sought a possible correlation between sun exposure habits and venous thromboembolism (VTE) events. Methods: This was a cohort study comprising 40 000 women (1000 per year of age from 25 to 64 years) who were drawn from the southern Swedish population registry for 1990 and followed for a mean of 11 years. Seventy-four per cent answered an inquiry at the inception of the study (n = 29 518), and provided detailed information on their sun exposure habits. Cox regression analysis was used with the presence of VTE as a dependent variable and selected demographics as independent variables. The... (More)
- Background: Venous and arterial thrombotic complications exhibit a seasonal variation, with risk peaking in winter and dropping to a nadir in summer. We sought a possible correlation between sun exposure habits and venous thromboembolism (VTE) events. Methods: This was a cohort study comprising 40 000 women (1000 per year of age from 25 to 64 years) who were drawn from the southern Swedish population registry for 1990 and followed for a mean of 11 years. Seventy-four per cent answered an inquiry at the inception of the study (n = 29 518), and provided detailed information on their sun exposure habits. Cox regression analysis was used with the presence of VTE as a dependent variable and selected demographics as independent variables. The main outcome was the relationship between VTE and sun exposure habits. Results: Swedish women who sunbathed during the summer, on winter vacations, or when abroad, or used a tanning bed, were at 30% lower risk of VTE than those who did not. Risk estimates did not change substantially after adjustment for demographic variables. The risk of VTE increased by 50% in winter as compared to the other seasons; the lowest risk was found in the summer. Conclusions: Women with more active sun exposure habits were at a significantly lower risk of VTE. We speculate that greater ultraviolet B light exposure improves a person's vitamin D status, which in turn enhances anticoagulant properties and enhances the cytokine profile. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1401792
- author
- Lindqvist, P. G.
; Epstein, Elisabeth
LU
and Olsson, Håkan
LU
- organization
- publishing date
- 2009
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- sun exposure habits, venous thromboembolism
- in
- Journal of Thrombosis and Haemostasis
- volume
- 7
- issue
- 4
- pages
- 605 - 610
- publisher
- Elsevier
- external identifiers
-
- wos:000264373800015
- scopus:63049101206
- ISSN
- 1538-7933
- DOI
- 10.1111/j.1538-7836.2009.03312.x
- language
- English
- LU publication?
- yes
- id
- f564874a-4b20-4f66-aab8-b0e83367d615 (old id 1401792)
- date added to LUP
- 2016-04-01 12:15:58
- date last changed
- 2025-01-15 12:22:13
@article{f564874a-4b20-4f66-aab8-b0e83367d615,
abstract = {{Background: Venous and arterial thrombotic complications exhibit a seasonal variation, with risk peaking in winter and dropping to a nadir in summer. We sought a possible correlation between sun exposure habits and venous thromboembolism (VTE) events. Methods: This was a cohort study comprising 40 000 women (1000 per year of age from 25 to 64 years) who were drawn from the southern Swedish population registry for 1990 and followed for a mean of 11 years. Seventy-four per cent answered an inquiry at the inception of the study (n = 29 518), and provided detailed information on their sun exposure habits. Cox regression analysis was used with the presence of VTE as a dependent variable and selected demographics as independent variables. The main outcome was the relationship between VTE and sun exposure habits. Results: Swedish women who sunbathed during the summer, on winter vacations, or when abroad, or used a tanning bed, were at 30% lower risk of VTE than those who did not. Risk estimates did not change substantially after adjustment for demographic variables. The risk of VTE increased by 50% in winter as compared to the other seasons; the lowest risk was found in the summer. Conclusions: Women with more active sun exposure habits were at a significantly lower risk of VTE. We speculate that greater ultraviolet B light exposure improves a person's vitamin D status, which in turn enhances anticoagulant properties and enhances the cytokine profile.}},
author = {{Lindqvist, P. G. and Epstein, Elisabeth and Olsson, Håkan}},
issn = {{1538-7933}},
keywords = {{sun exposure habits; venous thromboembolism}},
language = {{eng}},
number = {{4}},
pages = {{605--610}},
publisher = {{Elsevier}},
series = {{Journal of Thrombosis and Haemostasis}},
title = {{Does an active sun exposure habit lower the risk of venous thrombotic events? A D-lightful hypothesis}},
url = {{http://dx.doi.org/10.1111/j.1538-7836.2009.03312.x}},
doi = {{10.1111/j.1538-7836.2009.03312.x}},
volume = {{7}},
year = {{2009}},
}