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Protein microchip bioassay with dual fluorescent- and MALDI read-out.

Finnskog, David LU ; Ressine, Anton LU ; Laurell, Thomas LU and Marko-Varga, György LU (2005) 8th International Conference on Miniaturized Systems for Chemistry and Life Sciences In Micro Total Analysis Systems 2004, Vol 1 p.466-468
Abstract
Protein Microchip Array technology makes it possible to examine patterns of protein expressions and modifications. Current technologies such as two-dimensional get electrophoresis (2-DE) in combination with mass spectrometry allows the identification of biologically relevant proteins with high resolving power, but has also considerable limitations. Most spots observed in 2-DE are from high abundance proteins while low signaling proteins are highly suppressed. Protein microarrays have a potential to speed up the discovery of new markers and targets of interest to the pharmaceutical industry. The technique is also readily compatible with high-throughput applications.
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author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
fluorescence readout, MALDI-TOF read-out, immunoassay
in
Micro Total Analysis Systems 2004, Vol 1
issue
296
pages
466 - 468
publisher
Springer
conference name
8th International Conference on Miniaturized Systems for Chemistry and Life Sciences
external identifiers
  • wos:000228997000156
ISSN
0260-6291
language
English
LU publication?
yes
id
56058b2a-5c2c-4075-9219-b97a83d2f611 (old id 1406260)
date added to LUP
2009-06-08 10:49:03
date last changed
2016-08-16 15:20:51
@inproceedings{56058b2a-5c2c-4075-9219-b97a83d2f611,
  abstract     = {Protein Microchip Array technology makes it possible to examine patterns of protein expressions and modifications. Current technologies such as two-dimensional get electrophoresis (2-DE) in combination with mass spectrometry allows the identification of biologically relevant proteins with high resolving power, but has also considerable limitations. Most spots observed in 2-DE are from high abundance proteins while low signaling proteins are highly suppressed. Protein microarrays have a potential to speed up the discovery of new markers and targets of interest to the pharmaceutical industry. The technique is also readily compatible with high-throughput applications.},
  author       = {Finnskog, David and Ressine, Anton and Laurell, Thomas and Marko-Varga, György},
  booktitle    = {Micro Total Analysis Systems 2004, Vol 1},
  issn         = {0260-6291},
  keyword      = {fluorescence readout,MALDI-TOF read-out,immunoassay},
  language     = {eng},
  number       = {296},
  pages        = {466--468},
  publisher    = {Springer},
  title        = {Protein microchip bioassay with dual fluorescent- and MALDI read-out.},
  year         = {2005},
}