Advanced

Incidence of Retinopathy of Prematurity in Infants Born Before 27 Weeks' Gestation in Sweden

Austeng, Dordi; Källén, Karin LU ; Ewald, Uwe W.; Jakobsson, Peter G. and Holmstrom, Gerd E. (2009) In Archives of Ophthalmology 127(10). p.1315-1319
Abstract
Objective: To determine the incidence of retinopathy of prematurity (ROP) in extremely preterm infants born before 27 weeks' gestation in Sweden during a 3-year period. Methods: A national, prospective, population-based study was performed in Sweden from April 1, 2004, to March 31, 2007. The ophthalmologic part of the study was separately organized, and screening for ROP was performed beginning postnatal week 5. The criteria for the treatment of ROP agreed with the recommendations of the Early Treatment for Retinopathy of Prematurity Cooperative Group. Results: During the study, 506 of 707 live-born infants survived until the first eye examination. Of these, 368 (72.7%) had ROP: 37.9% had mild ROP and 34.8% had severe ROP. Ninety-nine... (More)
Objective: To determine the incidence of retinopathy of prematurity (ROP) in extremely preterm infants born before 27 weeks' gestation in Sweden during a 3-year period. Methods: A national, prospective, population-based study was performed in Sweden from April 1, 2004, to March 31, 2007. The ophthalmologic part of the study was separately organized, and screening for ROP was performed beginning postnatal week 5. The criteria for the treatment of ROP agreed with the recommendations of the Early Treatment for Retinopathy of Prematurity Cooperative Group. Results: During the study, 506 of 707 live-born infants survived until the first eye examination. Of these, 368 (72.7%) had ROP: 37.9% had mild ROP and 34.8% had severe ROP. Ninety-nine infants (19.6%) were treated. Gestational age at birth was a stronger predictor of ROP than was birth weight. A log-linear relationship between severe ROP and gestational age at birth was found in the present cohort, and the risk of ROP was reduced by 50% for each week of increase in gestational age at birth. Conclusions: Today, extremely preterm infants are surviving, and this population-based study with ROP as a primary outcome shows a higher incidence of this condition than in previously reported national cohorts. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Archives of Ophthalmology
volume
127
issue
10
pages
1315 - 1319
publisher
American Medical Association
external identifiers
  • wos:000270679900011
  • scopus:70350731214
ISSN
0003-9950
language
English
LU publication?
yes
id
c2f21717-acd3-4624-b7ca-a5bc1a4234ad (old id 1507641)
date added to LUP
2009-11-19 16:04:46
date last changed
2017-09-03 03:55:28
@article{c2f21717-acd3-4624-b7ca-a5bc1a4234ad,
  abstract     = {Objective: To determine the incidence of retinopathy of prematurity (ROP) in extremely preterm infants born before 27 weeks' gestation in Sweden during a 3-year period. Methods: A national, prospective, population-based study was performed in Sweden from April 1, 2004, to March 31, 2007. The ophthalmologic part of the study was separately organized, and screening for ROP was performed beginning postnatal week 5. The criteria for the treatment of ROP agreed with the recommendations of the Early Treatment for Retinopathy of Prematurity Cooperative Group. Results: During the study, 506 of 707 live-born infants survived until the first eye examination. Of these, 368 (72.7%) had ROP: 37.9% had mild ROP and 34.8% had severe ROP. Ninety-nine infants (19.6%) were treated. Gestational age at birth was a stronger predictor of ROP than was birth weight. A log-linear relationship between severe ROP and gestational age at birth was found in the present cohort, and the risk of ROP was reduced by 50% for each week of increase in gestational age at birth. Conclusions: Today, extremely preterm infants are surviving, and this population-based study with ROP as a primary outcome shows a higher incidence of this condition than in previously reported national cohorts.},
  author       = {Austeng, Dordi and Källén, Karin and Ewald, Uwe W. and Jakobsson, Peter G. and Holmstrom, Gerd E.},
  issn         = {0003-9950},
  language     = {eng},
  number       = {10},
  pages        = {1315--1319},
  publisher    = {American Medical Association},
  series       = {Archives of Ophthalmology},
  title        = {Incidence of Retinopathy of Prematurity in Infants Born Before 27 Weeks' Gestation in Sweden},
  volume       = {127},
  year         = {2009},
}