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Hemodynamics and jugular venous oxygen saturation during carotid endarterectomy: a comparison between general and locoregional anesthesia.

Dias, Nuno LU ; Kölbel, Tilo LU ; Goncalves, Isabel LU ; Chew, Michelle; Jeppsson Wistrand, Ulla and Brunkwall, Per (2010) In International Angiology 29(3). p.232-238
Abstract
AIM: To study hemodynamic and blood oxygenation changes in patients undergoing carotid endarterectomy (CEA) under general (GA) or locoregional (LRA) anesthesia. METHODS: Prospective non-randomized study including 50 patients undergoing CEA (31 men, mean age 72 (range 50-84) years-old under GA (N.=23) or LRA (N.=27). Systemic blood pressure, ECG, venous oxygen saturation in the ipsilateral jugular bulb and pulse-oximetry were monitored. Blood-gas analysis was done from blood obtained from the radial artery and ipsilateral jugular vein. RESULTS: Pulse rate and systemic systolic blood pressure were higher in LRA compared to the GA before, during and after cross clamping (P<0.05). Seven GA patients required dopamine-infusion to maintain... (More)
AIM: To study hemodynamic and blood oxygenation changes in patients undergoing carotid endarterectomy (CEA) under general (GA) or locoregional (LRA) anesthesia. METHODS: Prospective non-randomized study including 50 patients undergoing CEA (31 men, mean age 72 (range 50-84) years-old under GA (N.=23) or LRA (N.=27). Systemic blood pressure, ECG, venous oxygen saturation in the ipsilateral jugular bulb and pulse-oximetry were monitored. Blood-gas analysis was done from blood obtained from the radial artery and ipsilateral jugular vein. RESULTS: Pulse rate and systemic systolic blood pressure were higher in LRA compared to the GA before, during and after cross clamping (P<0.05). Seven GA patients required dopamine-infusion to maintain systolic blood pressure >120 mmHg. Jugular venous saturation was initially identical in both groups, but decreased significantly upon cross clamping in LRA compared to GA (P<0.05). This difference remained at least 3 minutes after cross clamp release (P<0.05). CONCLUSION: Patients under LRA seem to have increased sympathetic activity compared to patients under GA, as expressed by higher pulse rates and systolic blood pressures. Jugular venous saturation was lower during clamping of LRA patients. The differences were small and concur with the near-equality findings in studies analysing the clinical outcome. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
International Angiology
volume
29
issue
3
pages
232 - 238
publisher
Minerva Medica
external identifiers
  • wos:000281130900005
  • pmid:20502409
  • scopus:77956089273
ISSN
1827-1839
language
English
LU publication?
yes
id
6504cb36-a080-4026-be54-05abfbdcfc19 (old id 1609942)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/20502409?dopt=Abstract
date added to LUP
2010-06-02 11:47:19
date last changed
2018-05-29 11:40:06
@article{6504cb36-a080-4026-be54-05abfbdcfc19,
  abstract     = {AIM: To study hemodynamic and blood oxygenation changes in patients undergoing carotid endarterectomy (CEA) under general (GA) or locoregional (LRA) anesthesia. METHODS: Prospective non-randomized study including 50 patients undergoing CEA (31 men, mean age 72 (range 50-84) years-old under GA (N.=23) or LRA (N.=27). Systemic blood pressure, ECG, venous oxygen saturation in the ipsilateral jugular bulb and pulse-oximetry were monitored. Blood-gas analysis was done from blood obtained from the radial artery and ipsilateral jugular vein. RESULTS: Pulse rate and systemic systolic blood pressure were higher in LRA compared to the GA before, during and after cross clamping (P&lt;0.05). Seven GA patients required dopamine-infusion to maintain systolic blood pressure &gt;120 mmHg. Jugular venous saturation was initially identical in both groups, but decreased significantly upon cross clamping in LRA compared to GA (P&lt;0.05). This difference remained at least 3 minutes after cross clamp release (P&lt;0.05). CONCLUSION: Patients under LRA seem to have increased sympathetic activity compared to patients under GA, as expressed by higher pulse rates and systolic blood pressures. Jugular venous saturation was lower during clamping of LRA patients. The differences were small and concur with the near-equality findings in studies analysing the clinical outcome.},
  author       = {Dias, Nuno and Kölbel, Tilo and Goncalves, Isabel and Chew, Michelle and Jeppsson Wistrand, Ulla and Brunkwall, Per},
  issn         = {1827-1839},
  language     = {eng},
  number       = {3},
  pages        = {232--238},
  publisher    = {Minerva Medica},
  series       = {International Angiology},
  title        = {Hemodynamics and jugular venous oxygen saturation during carotid endarterectomy: a comparison between general and locoregional anesthesia.},
  volume       = {29},
  year         = {2010},
}