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Rose Hip and Lactobacillus plantarum DSM 9843 Reduce Ischemia/Reperfusion Injury in the Mouse Colon.

Hakansson, A ; Stene, Christina LU ; Röme, Andrada LU ; Molin, Göran LU ; Ahrné, Siv LU ; Thorlacius, Henrik LU and Jeppsson, Bengt LU (2006) In Digestive Diseases and Sciences 51(11). p.2094-2101
Abstract
schaemia/reperfusion (I/R) of the colon is an inflammatory condition that leads to tissue injury where reactive oxygen species play a central role. Rose hip is rich in biologically active polyphenols with antioxidative properties, which may be important in prevention of lipid peroxidation. L. plantarum DSM 9843 possesses enzymatic activity towards polyphenols. The objective of this study was to define the effect of oral administration of L. plantarum and rose hip in I/R injury. Administration of rose hip and L. plantarum significantly decreased MDA levels in caecum tissue and Enterobacteriaceae counts in caecum stool. A positive correlation between MDA levels and Enterobacteriaceae counts was found. The results support a... (More)
schaemia/reperfusion (I/R) of the colon is an inflammatory condition that leads to tissue injury where reactive oxygen species play a central role. Rose hip is rich in biologically active polyphenols with antioxidative properties, which may be important in prevention of lipid peroxidation. L. plantarum DSM 9843 possesses enzymatic activity towards polyphenols. The objective of this study was to define the effect of oral administration of L. plantarum and rose hip in I/R injury. Administration of rose hip and L. plantarum significantly decreased MDA levels in caecum tissue and Enterobacteriaceae counts in caecum stool. A positive correlation between MDA levels and Enterobacteriaceae counts was found. The results support a synergistic/additive role of rose hip and L. plantarum in reducing lipid peroxidation. Therefore rose hip and L. plantarum may be used as a pretreatment to tissue injuries, e.g. colonic surgery, organ transplantation and vascular surgery. (Less)
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author
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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
reperfusion, ischaemia, rose hip, polyphenols, lactobacilli
in
Digestive Diseases and Sciences
volume
51
issue
11
pages
2094 - 2101
publisher
Springer
external identifiers
  • wos:000242323500035
  • scopus:33751547256
ISSN
1573-2568
DOI
10.1007/s10620-006-9170-9
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Surgery Research Unit (013242220), Applied Nutrition and Food Chemistry (011001300), Emergency medicine/Medicine/Surgery (013240200)
id
37162d02-5700-46fc-9ae7-3120b39e1372 (old id 162491)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17009115&dopt=Abstract
date added to LUP
2016-04-01 11:43:42
date last changed
2020-02-19 01:46:19
@article{37162d02-5700-46fc-9ae7-3120b39e1372,
  abstract     = {schaemia/reperfusion (I/R) of the colon is an inflammatory condition that leads to tissue injury where reactive oxygen species play a central role. Rose hip is rich in biologically active polyphenols with antioxidative properties, which may be important in prevention of lipid peroxidation. L. plantarum DSM 9843 possesses enzymatic activity towards polyphenols. The objective of this study was to define the effect of oral administration of L. plantarum and rose hip in I/R injury. Administration of rose hip and L. plantarum significantly decreased MDA levels in caecum tissue and Enterobacteriaceae counts in caecum stool. A positive correlation between MDA levels and Enterobacteriaceae counts was found. The results support a synergistic/additive role of rose hip and L. plantarum in reducing lipid peroxidation. Therefore rose hip and L. plantarum may be used as a pretreatment to tissue injuries, e.g. colonic surgery, organ transplantation and vascular surgery.},
  author       = {Hakansson, A and Stene, Christina and Röme, Andrada and Molin, Göran and Ahrné, Siv and Thorlacius, Henrik and Jeppsson, Bengt},
  issn         = {1573-2568},
  language     = {eng},
  number       = {11},
  pages        = {2094--2101},
  publisher    = {Springer},
  series       = {Digestive Diseases and Sciences},
  title        = {Rose Hip and Lactobacillus plantarum DSM 9843 Reduce Ischemia/Reperfusion Injury in the Mouse Colon.},
  url          = {https://lup.lub.lu.se/search/ws/files/2614195/625703.pdf},
  doi          = {10.1007/s10620-006-9170-9},
  volume       = {51},
  year         = {2006},
}