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Histology-specific risks in testicular cancer in immigrants to Sweden

Hemminki, Kari LU ; Mousavi, Seyed Mohsen; Brandt, Andreas; Ji, Jianguang LU and Sundquist, Jan LU (2010) In Endocrine-Related Cancer 17(2). p.329-334
Abstract
The changes of cancer incidence upon immigration have been used as an estimator of environmental influence on cancer risk. The previous immigrant studies have indicated that the origins of testicular cancer are at an early age in life, probably in the intrauterine period. We wanted to reexamine the critical periods on histology-specific testicular cancer in sons of immigrants to Sweden. We used the nationwide Swedish Family-Cancer Database to calculate standardized incidence ratios (SIRs) for testicular cancer in sons of parents immigrating to Sweden from low-and high-risk countries compared with the native Swedes. Among the large immigrant groups, the SIRs for sons of two Finnish and Asian parents were decreased if the sons were born... (More)
The changes of cancer incidence upon immigration have been used as an estimator of environmental influence on cancer risk. The previous immigrant studies have indicated that the origins of testicular cancer are at an early age in life, probably in the intrauterine period. We wanted to reexamine the critical periods on histology-specific testicular cancer in sons of immigrants to Sweden. We used the nationwide Swedish Family-Cancer Database to calculate standardized incidence ratios (SIRs) for testicular cancer in sons of parents immigrating to Sweden from low-and high-risk countries compared with the native Swedes. Among the large immigrant groups, the SIRs for sons of two Finnish and Asian parents were decreased if the sons were born outside Sweden. The sons of a Danish immigrant couple showed an increased risk of testicular cancer. The changes in SIR were most systematic for seminoma. The present patterns of testicular cancer risk among sons of immigrants point to the early environmental risk factors, which influence the risk probably after the intrauterine period. These factors appear to influence seminoma risk in a more enduring way than they influence non-seminoma. Endocrine-Related Cancer (2010) 17 329-334 (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Endocrine-Related Cancer
volume
17
issue
2
pages
329 - 334
publisher
Society for Endocrinology
external identifiers
  • wos:000279341700007
  • scopus:77953604420
ISSN
1479-6821
DOI
10.1677/ERC-09-0284
language
English
LU publication?
yes
id
2f451d66-c24d-4256-934c-d23b1685edd9 (old id 1629249)
date added to LUP
2010-07-22 10:17:28
date last changed
2018-05-29 12:22:33
@article{2f451d66-c24d-4256-934c-d23b1685edd9,
  abstract     = {The changes of cancer incidence upon immigration have been used as an estimator of environmental influence on cancer risk. The previous immigrant studies have indicated that the origins of testicular cancer are at an early age in life, probably in the intrauterine period. We wanted to reexamine the critical periods on histology-specific testicular cancer in sons of immigrants to Sweden. We used the nationwide Swedish Family-Cancer Database to calculate standardized incidence ratios (SIRs) for testicular cancer in sons of parents immigrating to Sweden from low-and high-risk countries compared with the native Swedes. Among the large immigrant groups, the SIRs for sons of two Finnish and Asian parents were decreased if the sons were born outside Sweden. The sons of a Danish immigrant couple showed an increased risk of testicular cancer. The changes in SIR were most systematic for seminoma. The present patterns of testicular cancer risk among sons of immigrants point to the early environmental risk factors, which influence the risk probably after the intrauterine period. These factors appear to influence seminoma risk in a more enduring way than they influence non-seminoma. Endocrine-Related Cancer (2010) 17 329-334},
  author       = {Hemminki, Kari and Mousavi, Seyed Mohsen and Brandt, Andreas and Ji, Jianguang and Sundquist, Jan},
  issn         = {1479-6821},
  language     = {eng},
  number       = {2},
  pages        = {329--334},
  publisher    = {Society for Endocrinology},
  series       = {Endocrine-Related Cancer},
  title        = {Histology-specific risks in testicular cancer in immigrants to Sweden},
  url          = {http://dx.doi.org/10.1677/ERC-09-0284},
  volume       = {17},
  year         = {2010},
}