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Cell polarity and the control of apical growth in Streptomyces.

Flärdh, Klas LU (2010) In Current Opinion in Microbiology 13(6). p.758-765
Abstract
Streptomyces cells grow by building cell wall at one pole-the hyphal tip. Although analogous to hyphal growth in fungi, this is achieved in a prokaryote, without any of the well-known eukaryotic cell polarity proteins, and it is also unique among bacterial cases of cell polarity. Further, polar growth of Streptomyces and the related mycobacteria and corynebacteria is independent of the MreB cytoskeleton and involves a number of coiled-coil proteins, including the polarity determinant DivIVA. Recent progress sheds light on targeting of DivIVA to hyphal tips and highlight protein phosphorylation in the regulation of actinobacterial growth. Furthermore, cell polarity affects not only cell envelope biogenesis in Streptomyces, but apparently... (More)
Streptomyces cells grow by building cell wall at one pole-the hyphal tip. Although analogous to hyphal growth in fungi, this is achieved in a prokaryote, without any of the well-known eukaryotic cell polarity proteins, and it is also unique among bacterial cases of cell polarity. Further, polar growth of Streptomyces and the related mycobacteria and corynebacteria is independent of the MreB cytoskeleton and involves a number of coiled-coil proteins, including the polarity determinant DivIVA. Recent progress sheds light on targeting of DivIVA to hyphal tips and highlight protein phosphorylation in the regulation of actinobacterial growth. Furthermore, cell polarity affects not only cell envelope biogenesis in Streptomyces, but apparently also assembly of fimbriae, conjugation and migration of nucleoids. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Current Opinion in Microbiology
volume
13
issue
6
pages
758 - 765
publisher
Elsevier
external identifiers
  • wos:000285657400016
  • scopus:78649665296
ISSN
1879-0364
DOI
10.1016/j.mib.2010.10.002
language
English
LU publication?
yes
id
b6421138-a367-4aec-9a16-6bd0c1447a00 (old id 1732524)
date added to LUP
2010-12-13 15:43:16
date last changed
2018-05-29 11:14:32
@article{b6421138-a367-4aec-9a16-6bd0c1447a00,
  abstract     = {Streptomyces cells grow by building cell wall at one pole-the hyphal tip. Although analogous to hyphal growth in fungi, this is achieved in a prokaryote, without any of the well-known eukaryotic cell polarity proteins, and it is also unique among bacterial cases of cell polarity. Further, polar growth of Streptomyces and the related mycobacteria and corynebacteria is independent of the MreB cytoskeleton and involves a number of coiled-coil proteins, including the polarity determinant DivIVA. Recent progress sheds light on targeting of DivIVA to hyphal tips and highlight protein phosphorylation in the regulation of actinobacterial growth. Furthermore, cell polarity affects not only cell envelope biogenesis in Streptomyces, but apparently also assembly of fimbriae, conjugation and migration of nucleoids.},
  author       = {Flärdh, Klas},
  issn         = {1879-0364},
  language     = {eng},
  number       = {6},
  pages        = {758--765},
  publisher    = {Elsevier},
  series       = {Current Opinion in Microbiology},
  title        = {Cell polarity and the control of apical growth in Streptomyces.},
  url          = {http://dx.doi.org/10.1016/j.mib.2010.10.002},
  volume       = {13},
  year         = {2010},
}