Cell polarity and the control of apical growth in Streptomyces.
(2010) In Current Opinion in Microbiology 13(6). p.758-765- Abstract
- Streptomyces cells grow by building cell wall at one pole-the hyphal tip. Although analogous to hyphal growth in fungi, this is achieved in a prokaryote, without any of the well-known eukaryotic cell polarity proteins, and it is also unique among bacterial cases of cell polarity. Further, polar growth of Streptomyces and the related mycobacteria and corynebacteria is independent of the MreB cytoskeleton and involves a number of coiled-coil proteins, including the polarity determinant DivIVA. Recent progress sheds light on targeting of DivIVA to hyphal tips and highlight protein phosphorylation in the regulation of actinobacterial growth. Furthermore, cell polarity affects not only cell envelope biogenesis in Streptomyces, but apparently... (More)
- Streptomyces cells grow by building cell wall at one pole-the hyphal tip. Although analogous to hyphal growth in fungi, this is achieved in a prokaryote, without any of the well-known eukaryotic cell polarity proteins, and it is also unique among bacterial cases of cell polarity. Further, polar growth of Streptomyces and the related mycobacteria and corynebacteria is independent of the MreB cytoskeleton and involves a number of coiled-coil proteins, including the polarity determinant DivIVA. Recent progress sheds light on targeting of DivIVA to hyphal tips and highlight protein phosphorylation in the regulation of actinobacterial growth. Furthermore, cell polarity affects not only cell envelope biogenesis in Streptomyces, but apparently also assembly of fimbriae, conjugation and migration of nucleoids. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1732524
- author
- Flärdh, Klas LU
- organization
- publishing date
- 2010
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Current Opinion in Microbiology
- volume
- 13
- issue
- 6
- pages
- 758 - 765
- publisher
- Elsevier
- external identifiers
-
- wos:000285657400016
- scopus:78649665296
- pmid:21036658
- ISSN
- 1879-0364
- DOI
- 10.1016/j.mib.2010.10.002
- language
- English
- LU publication?
- yes
- id
- b6421138-a367-4aec-9a16-6bd0c1447a00 (old id 1732524)
- date added to LUP
- 2016-04-01 10:32:21
- date last changed
- 2024-01-06 19:09:30
@article{b6421138-a367-4aec-9a16-6bd0c1447a00,
abstract = {{Streptomyces cells grow by building cell wall at one pole-the hyphal tip. Although analogous to hyphal growth in fungi, this is achieved in a prokaryote, without any of the well-known eukaryotic cell polarity proteins, and it is also unique among bacterial cases of cell polarity. Further, polar growth of Streptomyces and the related mycobacteria and corynebacteria is independent of the MreB cytoskeleton and involves a number of coiled-coil proteins, including the polarity determinant DivIVA. Recent progress sheds light on targeting of DivIVA to hyphal tips and highlight protein phosphorylation in the regulation of actinobacterial growth. Furthermore, cell polarity affects not only cell envelope biogenesis in Streptomyces, but apparently also assembly of fimbriae, conjugation and migration of nucleoids.}},
author = {{Flärdh, Klas}},
issn = {{1879-0364}},
language = {{eng}},
number = {{6}},
pages = {{758--765}},
publisher = {{Elsevier}},
series = {{Current Opinion in Microbiology}},
title = {{Cell polarity and the control of apical growth in Streptomyces.}},
url = {{http://dx.doi.org/10.1016/j.mib.2010.10.002}},
doi = {{10.1016/j.mib.2010.10.002}},
volume = {{13}},
year = {{2010}},
}