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Screening for Retinopathy of Prematurity in Infants Born Before 27 Weeks' Gestation in Sweden

Austeng, Dordi; Källén, Karin LU ; Hellstrom, Ann; Jakobsson, Peter G.; Johansson, Kent; Tornqvist, Kristina LU ; Wallin, Agneta and Holmstrom, Gerd E. (2011) In Archives of Ophthalmology 129(2). p.167-172
Abstract
Objective: To analyze screening for retinopathy of prematurity (ROP) during a 3-year period in a national cohort of infants born before 27 weeks' gestation. Methods: A national prospective study of neonatal morbidity in extremely preterm infants was performed in Sweden between April 1, 2004, and March 31, 2007. Screening for ROP was to start in the fifth postnatal week and to continue weekly until complete vascularization of the retina or until regression of ROP. Results: The first eye examination was performed no later than the sixth postnatal week in 84.8% of 506 infants, and the last examination was performed at postmenstrual age (PMA) of 38 weeks or later in 96.2% of infants. The mean and median numbers of days between examinations in... (More)
Objective: To analyze screening for retinopathy of prematurity (ROP) during a 3-year period in a national cohort of infants born before 27 weeks' gestation. Methods: A national prospective study of neonatal morbidity in extremely preterm infants was performed in Sweden between April 1, 2004, and March 31, 2007. Screening for ROP was to start in the fifth postnatal week and to continue weekly until complete vascularization of the retina or until regression of ROP. Results: The first eye examination was performed no later than the sixth postnatal week in 84.8% of 506 infants, and the last examination was performed at postmenstrual age (PMA) of 38 weeks or later in 96.2% of infants. The mean and median numbers of days between examinations in the total cohort were 8.6 and 7.9 days, respectively (range, 1-27.8 days), and the mean and me-dian numbers of examinations were 12 and 10, respectively. Most infants were treated during a limited period (eg, at PMA of 39 weeks, 75.0% of infants had been treated). Conclusions: The objective of screening for ROP is timely detection of ROP before reaching treatment of criteria, ie, type 1 ROP, according to the Early Treatment for ROP recommendations. In our population of infants born before 27 weeks' gestation, the first examination could safely be postponed until PMA of 31 weeks because the onset of ROP stage 3 did not occur before then and criteria for treatment were not reached before PMA of 32 weeks. Gestational age at birth and PMA at the time of examination should be considered when deciding when and where the next examination should be performed. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Archives of Ophthalmology
volume
129
issue
2
pages
167 - 172
publisher
American Medical Association
external identifiers
  • wos:000287329500008
  • scopus:79951603565
ISSN
0003-9950
DOI
10.1001/archophthalmol.2010.346
language
English
LU publication?
yes
id
ca3a318f-5024-45bc-a844-b8be16fab2ca (old id 1878190)
date added to LUP
2011-04-01 08:35:14
date last changed
2017-02-22 10:46:23
@article{ca3a318f-5024-45bc-a844-b8be16fab2ca,
  abstract     = {Objective: To analyze screening for retinopathy of prematurity (ROP) during a 3-year period in a national cohort of infants born before 27 weeks' gestation. Methods: A national prospective study of neonatal morbidity in extremely preterm infants was performed in Sweden between April 1, 2004, and March 31, 2007. Screening for ROP was to start in the fifth postnatal week and to continue weekly until complete vascularization of the retina or until regression of ROP. Results: The first eye examination was performed no later than the sixth postnatal week in 84.8% of 506 infants, and the last examination was performed at postmenstrual age (PMA) of 38 weeks or later in 96.2% of infants. The mean and median numbers of days between examinations in the total cohort were 8.6 and 7.9 days, respectively (range, 1-27.8 days), and the mean and me-dian numbers of examinations were 12 and 10, respectively. Most infants were treated during a limited period (eg, at PMA of 39 weeks, 75.0% of infants had been treated). Conclusions: The objective of screening for ROP is timely detection of ROP before reaching treatment of criteria, ie, type 1 ROP, according to the Early Treatment for ROP recommendations. In our population of infants born before 27 weeks' gestation, the first examination could safely be postponed until PMA of 31 weeks because the onset of ROP stage 3 did not occur before then and criteria for treatment were not reached before PMA of 32 weeks. Gestational age at birth and PMA at the time of examination should be considered when deciding when and where the next examination should be performed.},
  author       = {Austeng, Dordi and Källén, Karin and Hellstrom, Ann and Jakobsson, Peter G. and Johansson, Kent and Tornqvist, Kristina and Wallin, Agneta and Holmstrom, Gerd E.},
  issn         = {0003-9950},
  language     = {eng},
  number       = {2},
  pages        = {167--172},
  publisher    = {American Medical Association},
  series       = {Archives of Ophthalmology},
  title        = {Screening for Retinopathy of Prematurity in Infants Born Before 27 Weeks' Gestation in Sweden},
  url          = {http://dx.doi.org/10.1001/archophthalmol.2010.346},
  volume       = {129},
  year         = {2011},
}