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Visibility of single spiculations in digital breast tomosynthesis

Timberg, Pontus LU ; Dustler, Magnus LU ; Förnvik, Daniel LU and Zackrisson, Sophia LU (2013) SPIE Medical Imaging, 2013 8673. p.86731-86731
Abstract
Purpose: To investigate the visibility of single spiculations in digital breast tomosynthesis (DBT). Method: Simulated spheres (6 mm diameter) with single spiculations were added to projection images acquired on a DBT system (MAMMOMAT Inspiration, Siemens). The spiculations had a cylindrical shape and were randomly, diagonally aligned (at four different positions: +/- pi/4 or +/- 3 pi/4) at a plane parallel to the detector. They were assumed to consist of a fibroglandular tissue composition. The length of the spiculations was 5 mm while the diameter varied (0.12 - 0.28 mm). Reconstructed central slices of the lesion, separated by insertion in fatty or dense breasts (100 images in each), were used in 4-alternative forced choice (4AFC) human... (More)
Purpose: To investigate the visibility of single spiculations in digital breast tomosynthesis (DBT). Method: Simulated spheres (6 mm diameter) with single spiculations were added to projection images acquired on a DBT system (MAMMOMAT Inspiration, Siemens). The spiculations had a cylindrical shape and were randomly, diagonally aligned (at four different positions: +/- pi/4 or +/- 3 pi/4) at a plane parallel to the detector. They were assumed to consist of a fibroglandular tissue composition. The length of the spiculations was 5 mm while the diameter varied (0.12 - 0.28 mm). Reconstructed central slices of the lesion, separated by insertion in fatty or dense breasts (100 images in each), were used in 4-alternative forced choice (4AFC) human observer experiments. Three different reconstructions were used: filtered back projection (FBP) with 1 mm thick slices and a statistical artifact reduction reconstruction (SAR) method generating 1 and 2 mm thick slices. Five readers participated and their task was to locate the spiculation in randomly presented images from the whole image set (4 diameters x 100 images). The percent correct (PC) decision was determined in both fat and dense tissue for all spiculation diameters and reconstructions. Results: At a PC level of 95% the required diameter was about 0.17 - 0.22 mm in dense tissue, and 0.18 - 0.26 mm in fatty tissue (depending upon reconstruction). Conclusions: SAR was found to be a promising alternative to FBP. The visibility of single spiculations was determined. The required diameter depends on both tissue composition and reconstruction. (Less)
Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Breast Tomosynthesis, Lesion simulation, Spiculation, 4AFC, Reconstruction methods
host publication
Medical Imaging 2013: Image Perception, Observer Performance, And Technology Assessment
volume
8673
pages
86731 - 86731
publisher
SPIE
conference name
SPIE Medical Imaging, 2013
conference location
Lake Buena Vista (Orlando area), Florida, United States
conference dates
2013-02-09 - 2013-02-14
external identifiers
  • wos:000322986700045
  • scopus:84878800813
ISSN
0277-786X
1996-756X
DOI
10.1117/12.2005853
language
English
LU publication?
yes
id
187cd137-eeae-4b86-98e8-8fc2dc1588d7 (old id 4027042)
date added to LUP
2016-04-01 10:29:16
date last changed
2024-08-11 23:22:04
@inproceedings{187cd137-eeae-4b86-98e8-8fc2dc1588d7,
  abstract     = {{Purpose: To investigate the visibility of single spiculations in digital breast tomosynthesis (DBT). Method: Simulated spheres (6 mm diameter) with single spiculations were added to projection images acquired on a DBT system (MAMMOMAT Inspiration, Siemens). The spiculations had a cylindrical shape and were randomly, diagonally aligned (at four different positions: +/- pi/4 or +/- 3 pi/4) at a plane parallel to the detector. They were assumed to consist of a fibroglandular tissue composition. The length of the spiculations was 5 mm while the diameter varied (0.12 - 0.28 mm). Reconstructed central slices of the lesion, separated by insertion in fatty or dense breasts (100 images in each), were used in 4-alternative forced choice (4AFC) human observer experiments. Three different reconstructions were used: filtered back projection (FBP) with 1 mm thick slices and a statistical artifact reduction reconstruction (SAR) method generating 1 and 2 mm thick slices. Five readers participated and their task was to locate the spiculation in randomly presented images from the whole image set (4 diameters x 100 images). The percent correct (PC) decision was determined in both fat and dense tissue for all spiculation diameters and reconstructions. Results: At a PC level of 95% the required diameter was about 0.17 - 0.22 mm in dense tissue, and 0.18 - 0.26 mm in fatty tissue (depending upon reconstruction). Conclusions: SAR was found to be a promising alternative to FBP. The visibility of single spiculations was determined. The required diameter depends on both tissue composition and reconstruction.}},
  author       = {{Timberg, Pontus and Dustler, Magnus and Förnvik, Daniel and Zackrisson, Sophia}},
  booktitle    = {{Medical Imaging 2013: Image Perception, Observer Performance, And Technology Assessment}},
  issn         = {{0277-786X}},
  keywords     = {{Breast Tomosynthesis; Lesion simulation; Spiculation; 4AFC; Reconstruction methods}},
  language     = {{eng}},
  pages        = {{86731--86731}},
  publisher    = {{SPIE}},
  title        = {{Visibility of single spiculations in digital breast tomosynthesis}},
  url          = {{http://dx.doi.org/10.1117/12.2005853}},
  doi          = {{10.1117/12.2005853}},
  volume       = {{8673}},
  year         = {{2013}},
}