Advanced

Kinin System Activation in Vasculitis.

Kahn, Robin LU and Karpman, Diana LU (2011) In Acta paediatrica (Oslo, Norway : 1992) 100(7). p.950-957
Abstract
Vasculitis is a systemic autoimmune inflammatory disease, characterized by inflammation in and around vessel walls leading to perturbed vessel patency and tissue damage. Many different organs may be involved. In this review pathogenetic mechanisms of vasculitis are discussed, with special reference to activation of the kinin system. Mechanisms of kinin system activation are described ultimately leading to release of kinins from high-molecular-weight-kininogen. These vasoactive peptides promote inflammation. Conclusion: Kinin system activation during vasculitis promotes inflammation.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Children, Bradykinin, Kinin receptors, Proteinase 3, Vasculitis
in
Acta paediatrica (Oslo, Norway : 1992)
volume
100
issue
7
pages
950 - 957
publisher
Wiley-Blackwell Publishing Ltd
external identifiers
  • wos:000291224200019
  • pmid:21401717
  • scopus:79958036673
ISSN
1651-2227
DOI
10.1111/j.1651-2227.2011.02266.x
language
English
LU publication?
yes
id
1bb53ea7-e959-4ff9-ae8a-2d9f61975955 (old id 1883999)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/21401717?dopt=Abstract
date added to LUP
2011-04-01 15:50:29
date last changed
2017-01-01 05:27:12
@article{1bb53ea7-e959-4ff9-ae8a-2d9f61975955,
  abstract     = {Vasculitis is a systemic autoimmune inflammatory disease, characterized by inflammation in and around vessel walls leading to perturbed vessel patency and tissue damage. Many different organs may be involved. In this review pathogenetic mechanisms of vasculitis are discussed, with special reference to activation of the kinin system. Mechanisms of kinin system activation are described ultimately leading to release of kinins from high-molecular-weight-kininogen. These vasoactive peptides promote inflammation. Conclusion: Kinin system activation during vasculitis promotes inflammation.},
  author       = {Kahn, Robin and Karpman, Diana},
  issn         = {1651-2227},
  keyword      = {Children,Bradykinin,Kinin receptors,Proteinase 3,Vasculitis},
  language     = {eng},
  number       = {7},
  pages        = {950--957},
  publisher    = {Wiley-Blackwell Publishing Ltd},
  series       = {Acta paediatrica (Oslo, Norway : 1992)},
  title        = {Kinin System Activation in Vasculitis.},
  url          = {http://dx.doi.org/10.1111/j.1651-2227.2011.02266.x},
  volume       = {100},
  year         = {2011},
}