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Excess mortality in middle-aged men with diabetes aged 15-34 years at diagnosis.

Törn, Carina LU ; Ingemansson, Sofie LU ; Lindblad, Ulf LU and Gudbjörnsdottir, Soffia (2011) In Acta Diabetologica 48. p.197-202
Abstract
The aim of this study is to assess mortality risk and the excess of risk in patients with diabetes. Patients were 15-34 years old at diagnosis of diabetes mellitus (n = 879) in 1992 and 1993 in this national cohort from Sweden. Healthy controls were matched for gender and birth on the same day as the index cases (n = 837). The civic registration number was used to link patients and controls to the Swedish Cause of Death Registry. During follow-up, 3.3% (29/879) of patients and 1.1% (9/837; P = 0.002) of controls died. The risk for a patient with diabetes to die was almost threefold increased compared with healthy controls; hazard ratio, 2.9 (95% CI 1.4-6.2). This increased risk was significant in men; hazard ratio, 2.8 (95% CI 1.2-6.5).... (More)
The aim of this study is to assess mortality risk and the excess of risk in patients with diabetes. Patients were 15-34 years old at diagnosis of diabetes mellitus (n = 879) in 1992 and 1993 in this national cohort from Sweden. Healthy controls were matched for gender and birth on the same day as the index cases (n = 837). The civic registration number was used to link patients and controls to the Swedish Cause of Death Registry. During follow-up, 3.3% (29/879) of patients and 1.1% (9/837; P = 0.002) of controls died. The risk for a patient with diabetes to die was almost threefold increased compared with healthy controls; hazard ratio, 2.9 (95% CI 1.4-6.2). This increased risk was significant in men; hazard ratio, 2.8 (95% CI 1.2-6.5). Diabetes as the underlying cause of death accounted for 38% (11/29) of deaths among patients. Most patients, 55% (16/29), died at home, remaining patients in hospital, 28% (8/29), or elsewhere 17% (5/29) compared to controls of whom 33% (3/9; P = 0.45) died at home, 33% (3/9; P = 1.0) in hospital, and 33% (3/9; P = 0.36) elsewhere. Only 55% (16/29) of patients had a specified day of death on death certificates compared to 100% (9/9; P = 0.016) of controls. Adult men with diabetes had an almost threefold increased risk to die within 15 years of diagnosis compared to healthy men. Most middle-aged patients with diabetes died at home and often without a specified date of death recorded. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Diabetologica
volume
48
pages
197 - 202
publisher
Springer
external identifiers
  • WOS:000294344600004
  • PMID:21390553
  • Scopus:80052361682
ISSN
1432-5233
DOI
10.1007/s00592-011-0272-2
language
English
LU publication?
yes
id
ff5b3da5-6e7e-4f11-9053-93da864bcb4e (old id 1884126)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/21390553?dopt=Abstract
date added to LUP
2011-04-01 14:46:24
date last changed
2017-01-01 07:51:54
@article{ff5b3da5-6e7e-4f11-9053-93da864bcb4e,
  abstract     = {The aim of this study is to assess mortality risk and the excess of risk in patients with diabetes. Patients were 15-34 years old at diagnosis of diabetes mellitus (n = 879) in 1992 and 1993 in this national cohort from Sweden. Healthy controls were matched for gender and birth on the same day as the index cases (n = 837). The civic registration number was used to link patients and controls to the Swedish Cause of Death Registry. During follow-up, 3.3% (29/879) of patients and 1.1% (9/837; P = 0.002) of controls died. The risk for a patient with diabetes to die was almost threefold increased compared with healthy controls; hazard ratio, 2.9 (95% CI 1.4-6.2). This increased risk was significant in men; hazard ratio, 2.8 (95% CI 1.2-6.5). Diabetes as the underlying cause of death accounted for 38% (11/29) of deaths among patients. Most patients, 55% (16/29), died at home, remaining patients in hospital, 28% (8/29), or elsewhere 17% (5/29) compared to controls of whom 33% (3/9; P = 0.45) died at home, 33% (3/9; P = 1.0) in hospital, and 33% (3/9; P = 0.36) elsewhere. Only 55% (16/29) of patients had a specified day of death on death certificates compared to 100% (9/9; P = 0.016) of controls. Adult men with diabetes had an almost threefold increased risk to die within 15 years of diagnosis compared to healthy men. Most middle-aged patients with diabetes died at home and often without a specified date of death recorded.},
  author       = {Törn, Carina and Ingemansson, Sofie and Lindblad, Ulf and Gudbjörnsdottir, Soffia},
  issn         = {1432-5233},
  language     = {eng},
  pages        = {197--202},
  publisher    = {Springer},
  series       = {Acta Diabetologica},
  title        = {Excess mortality in middle-aged men with diabetes aged 15-34 years at diagnosis.},
  url          = {http://dx.doi.org/10.1007/s00592-011-0272-2},
  volume       = {48},
  year         = {2011},
}