Perfusion of human placenta with hemoglobin introduces preeclampsia-like injuries that are prevented by α(1)-microglobulin.
(2011) In Placenta 32(4). p.323-332- Abstract
- Preeclamptic women have increased plasma levels of free fetal hemoglobin (HbF), increased gene expression of placental HbF and accumulation of free HbF in the placental vascular lumen. Free hemoglobin (Hb) is pro-inflammatory, and causes oxidative stress and tissue damage.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1884552
- author
- organization
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Oxidative stress, Hemoglobin, Dual placental perfusion, Microarray, Electron microscopy, alpha(1)-microglobulin
- in
- Placenta
- volume
- 32
- issue
- 4
- pages
- 323 - 332
- publisher
- W.B. Saunders
- external identifiers
-
- wos:000289393500005
- pmid:21356557
- scopus:79952738574
- ISSN
- 1532-3102
- DOI
- 10.1016/j.placenta.2011.01.017
- language
- English
- LU publication?
- yes
- id
- 9f829aed-3386-46c2-bd65-9b3bef28185b (old id 1884552)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/21356557?dopt=Abstract
- date added to LUP
- 2016-04-01 10:42:20
- date last changed
- 2022-04-04 20:33:30
@article{9f829aed-3386-46c2-bd65-9b3bef28185b, abstract = {{Preeclamptic women have increased plasma levels of free fetal hemoglobin (HbF), increased gene expression of placental HbF and accumulation of free HbF in the placental vascular lumen. Free hemoglobin (Hb) is pro-inflammatory, and causes oxidative stress and tissue damage.}}, author = {{May, K and Wester Rosenlöf, Lena and Gram, Magnus and Centlow, Magnus and Mörgelin, Matthias and Larsson, Irene and Cederlund, Martin and Rutardottir, Sigurbjörg and Siegmund, W and Schneider, H and Åkerström, Bo and Hansson, Stefan}}, issn = {{1532-3102}}, keywords = {{Oxidative stress; Hemoglobin; Dual placental perfusion; Microarray; Electron microscopy; alpha(1)-microglobulin}}, language = {{eng}}, number = {{4}}, pages = {{323--332}}, publisher = {{W.B. Saunders}}, series = {{Placenta}}, title = {{Perfusion of human placenta with hemoglobin introduces preeclampsia-like injuries that are prevented by α(1)-microglobulin.}}, url = {{https://lup.lub.lu.se/search/files/2068328/1897739.pdf}}, doi = {{10.1016/j.placenta.2011.01.017}}, volume = {{32}}, year = {{2011}}, }