Hip fracture in men-survival and subsequent fractures: a cohort study with 22-year follow-up.
von Friesendorff, My LU ; McGuigan, Fiona LU
; Besjakov, Jack
LU
and Åkesson, Kristina
LU
(2011)
In Journal of the American Geriatrics Society
59(5).
p.806-813
- Abstract
- Abstract
OBJECTIVES:
To evaluate the influence of age on survival and risk of subsequent fracture in men with hip fracture, applying a residual lifetime perspective.
DESIGN:
Retrospective cohort study with 22-year follow-up.
SETTING:
Skåne University Hospital, Malmö, Sweden.
PARTICIPANTS:
Men aged 60 and older (N=226) with an index hip fracture during 1984/85.
MEASUREMENTS:
Twenty-two-year survival (mortality) and risk of new fractures evaluated in 5-year age bands and age groups (<75, 75-84, ≥85).
RESULTS:
Mean age was 78±9. Mortality at 22 years was 98%. Survivors were all... (More) - Abstract
OBJECTIVES:
To evaluate the influence of age on survival and risk of subsequent fracture in men with hip fracture, applying a residual lifetime perspective.
DESIGN:
Retrospective cohort study with 22-year follow-up.
SETTING:
Skåne University Hospital, Malmö, Sweden.
PARTICIPANTS:
Men aged 60 and older (N=226) with an index hip fracture during 1984/85.
MEASUREMENTS:
Twenty-two-year survival (mortality) and risk of new fractures evaluated in 5-year age bands and age groups (<75, 75-84, ≥85).
RESULTS:
Mean age was 78±9. Mortality at 22 years was 98%. Survivors were all younger than 75 at inclusion. Mortality was dependent on age at all time points (18%, 38%, 69% at 1 year, increasing to 71%, 93%, 100% by 10 years in <75, 75-84, ≥85, respectively). Median survival was 5.4 years, 2.0 years, and 3 months, respectively, in these age groups, and 33%, 27%, and 13% of each age-group sustained subsequent fractures, generally within 5 years. Overall 10-year fracture risk was 29% (95% confidence interval (CI)=19-38%), increasing to 44% (95% CI=30-58%) when adjusted for mortality. Residual lifetime risk of new fracture was 33% (95% CI=23-43%), and mortality-adjusted risk was 63% (95% CI=45-81%). Participants younger than 75 at index hip fracture were at greatest risk of new fracture (hazard ratio=2.7, 95% CI=1.1-6.4, P=.03).
CONCLUSION:
Almost one-third of men with hip fracture have subsequent fractures during their remaining lifetime. Time at risk is highly dependent on age. Most new fractures occur in relatively younger men and within 5 years, whereas most aged 75 and older die before experiencing a new fracture. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1972632
- author
- von Friesendorff, My
LU
; McGuigan, Fiona
LU
; Besjakov, Jack
LU
and Åkesson, Kristina
LU
- organization
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of the American Geriatrics Society
- volume
- 59
- issue
- 5
- pages
- 806 - 813
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000290578700004
- pmid:21568951
- scopus:79956039305
- ISSN
- 0002-8614
- DOI
- 10.1111/j.1532-5415.2011.03399.x
- language
- English
- LU publication?
- yes
- id
- 4a7f38d7-d15e-4250-9f74-8e215a402a33 (old id 1972632)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/21568951?dopt=Abstract
- date added to LUP
- 2016-04-04 08:55:11
- date last changed
- 2023-10-17 21:20:01
@article{4a7f38d7-d15e-4250-9f74-8e215a402a33,
abstract = {{Abstract<br/><br>
OBJECTIVES:<br/><br>
To evaluate the influence of age on survival and risk of subsequent fracture in men with hip fracture, applying a residual lifetime perspective.<br/><br>
<br/><br>
DESIGN:<br/><br>
Retrospective cohort study with 22-year follow-up.<br/><br>
<br/><br>
SETTING:<br/><br>
Skåne University Hospital, Malmö, Sweden.<br/><br>
<br/><br>
PARTICIPANTS:<br/><br>
Men aged 60 and older (N=226) with an index hip fracture during 1984/85.<br/><br>
<br/><br>
MEASUREMENTS:<br/><br>
Twenty-two-year survival (mortality) and risk of new fractures evaluated in 5-year age bands and age groups (<75, 75-84, ≥85).<br/><br>
<br/><br>
RESULTS:<br/><br>
Mean age was 78±9. Mortality at 22 years was 98%. Survivors were all younger than 75 at inclusion. Mortality was dependent on age at all time points (18%, 38%, 69% at 1 year, increasing to 71%, 93%, 100% by 10 years in <75, 75-84, ≥85, respectively). Median survival was 5.4 years, 2.0 years, and 3 months, respectively, in these age groups, and 33%, 27%, and 13% of each age-group sustained subsequent fractures, generally within 5 years. Overall 10-year fracture risk was 29% (95% confidence interval (CI)=19-38%), increasing to 44% (95% CI=30-58%) when adjusted for mortality. Residual lifetime risk of new fracture was 33% (95% CI=23-43%), and mortality-adjusted risk was 63% (95% CI=45-81%). Participants younger than 75 at index hip fracture were at greatest risk of new fracture (hazard ratio=2.7, 95% CI=1.1-6.4, P=.03).<br/><br>
<br/><br>
CONCLUSION:<br/><br>
Almost one-third of men with hip fracture have subsequent fractures during their remaining lifetime. Time at risk is highly dependent on age. Most new fractures occur in relatively younger men and within 5 years, whereas most aged 75 and older die before experiencing a new fracture.}},
author = {{von Friesendorff, My and McGuigan, Fiona and Besjakov, Jack and Åkesson, Kristina}},
issn = {{0002-8614}},
language = {{eng}},
number = {{5}},
pages = {{806--813}},
publisher = {{Wiley-Blackwell}},
series = {{Journal of the American Geriatrics Society}},
title = {{Hip fracture in men-survival and subsequent fractures: a cohort study with 22-year follow-up.}},
url = {{http://dx.doi.org/10.1111/j.1532-5415.2011.03399.x}},
doi = {{10.1111/j.1532-5415.2011.03399.x}},
volume = {{59}},
year = {{2011}},
}