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6-minute walk test before and after a weight reduction program in obese subjects.

Ekman, M J; Klintenberg, Maria LU ; Björck, U; Norström, Fredrik LU and Ridderstråle, Martin LU (2013) In Obesity 21(3). p.236-243
Abstract
Weight loss and physical activity have shown favorable effects on risks associated with obesity. It is therefore of interest to evaluate exercise capacity and related co-morbidities in obese patients. We present data from obese subjects evaluated by the 6-minute walk test (6MWT) before and after a 7.3 (6.1-8.2) month weight reduction program. 251 subjects completed the test at baseline (BMI 40.6 [36.9-44.6] kg/m(2) ) and 129 (51.4 %) repeated the test after intervention (BMI 35.6 [31.2-38.5] kg/m(2) ). The six minute walking distance (6MWD) at baseline (535 [480-580] m) and at follow up (599 [522-640] m) correlated to several cardiovascular risk markers. Age, weight, height, resting heart rate, smoking status, fP-glucose and use of... (More)
Weight loss and physical activity have shown favorable effects on risks associated with obesity. It is therefore of interest to evaluate exercise capacity and related co-morbidities in obese patients. We present data from obese subjects evaluated by the 6-minute walk test (6MWT) before and after a 7.3 (6.1-8.2) month weight reduction program. 251 subjects completed the test at baseline (BMI 40.6 [36.9-44.6] kg/m(2) ) and 129 (51.4 %) repeated the test after intervention (BMI 35.6 [31.2-38.5] kg/m(2) ). The six minute walking distance (6MWD) at baseline (535 [480-580] m) and at follow up (599 [522-640] m) correlated to several cardiovascular risk markers. Age, weight, height, resting heart rate, smoking status, fP-glucose and use of ß-blockers explained 43 % of the variance in predicted 6MWD at baseline. The effect of smoking status, fP-glucose, ß-blockers and resting heart rate lost significance at follow up. Presence of diabetes and the metabolic syndrome had a negative influence on 6MWD but did not affect the impact of intervention based on percentage increase in walking distance. Gender had no impact on 6MWD. Reported pain during the test was common but decreased after intervention (57.0 % vs. 28.7 %, p<0.001). In conclusion, the 6MWT may be used to evaluate intervention success beyond kilogram weight loss in obese subjects. We present formulas to predict 6MWD and the effect of weight loss on walking distance in clinical practice. Pain is a common problem which has to be considered when giving advice on exercise as a part of weight loss intervention. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Obesity
volume
21
issue
3
pages
236 - 243
publisher
Nature Publishing Group
external identifiers
  • wos:000322087600009
  • pmid:23404845
  • scopus:84876462393
ISSN
1930-739X
DOI
10.1002/oby.20046
language
English
LU publication?
yes
id
1a9fa5c7-ae5e-4d93-ba88-e00f4b124110 (old id 3559849)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/23404845?dopt=Abstract
date added to LUP
2013-03-04 10:52:21
date last changed
2019-06-11 01:15:07
@article{1a9fa5c7-ae5e-4d93-ba88-e00f4b124110,
  abstract     = {Weight loss and physical activity have shown favorable effects on risks associated with obesity. It is therefore of interest to evaluate exercise capacity and related co-morbidities in obese patients. We present data from obese subjects evaluated by the 6-minute walk test (6MWT) before and after a 7.3 (6.1-8.2) month weight reduction program. 251 subjects completed the test at baseline (BMI 40.6 [36.9-44.6] kg/m(2) ) and 129 (51.4 %) repeated the test after intervention (BMI 35.6 [31.2-38.5] kg/m(2) ). The six minute walking distance (6MWD) at baseline (535 [480-580] m) and at follow up (599 [522-640] m) correlated to several cardiovascular risk markers. Age, weight, height, resting heart rate, smoking status, fP-glucose and use of ß-blockers explained 43 % of the variance in predicted 6MWD at baseline. The effect of smoking status, fP-glucose, ß-blockers and resting heart rate lost significance at follow up. Presence of diabetes and the metabolic syndrome had a negative influence on 6MWD but did not affect the impact of intervention based on percentage increase in walking distance. Gender had no impact on 6MWD. Reported pain during the test was common but decreased after intervention (57.0 % vs. 28.7 %, p&lt;0.001). In conclusion, the 6MWT may be used to evaluate intervention success beyond kilogram weight loss in obese subjects. We present formulas to predict 6MWD and the effect of weight loss on walking distance in clinical practice. Pain is a common problem which has to be considered when giving advice on exercise as a part of weight loss intervention.},
  author       = {Ekman, M J and Klintenberg, Maria and Björck, U and Norström, Fredrik and Ridderstråle, Martin},
  issn         = {1930-739X},
  language     = {eng},
  number       = {3},
  pages        = {236--243},
  publisher    = {Nature Publishing Group},
  series       = {Obesity},
  title        = {6-minute walk test before and after a weight reduction program in obese subjects.},
  url          = {http://dx.doi.org/10.1002/oby.20046},
  volume       = {21},
  year         = {2013},
}