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Access of medication review for people living with dementia : An analysis of inequality using Swedish register data

Saha, Sanjib LU orcid ; Persson, Sofie LU ; Jarl, Johan LU orcid ; Trepel, Dominic ; Lenander, Cecilia LU ; Londos, Elisabet LU ; Midlöv, Patrik LU orcid ; Lawlor, Brian ; Toresson, Håkan LU and Gerdtham, Ulf-Göran LU orcid (2025) In Alzheimer's & dementia : the journal of the Alzheimer's Association 21(11).
Abstract
INTRODUCTION
This study examines medication reviews (MRs) among people living with dementia (PWD) in Sweden, focusing on frequency and factors influencing access.

METHODS
Using nationwide register data, all diagnosed PWD from 2010 to 2016 were assessed for MR receipt in 2015 and/or 2016. The analysis guided by the Andersen healthcare utilization framework, considered predisposing, enabling, and need-based factors through multiple logistic regression.

RESULTS
The MR rate was 16% in 2015, 21% in 2016, and 30% across both years. Increased MR likelihood was linked to higher comorbidity (adjusted odds ratio [aOR] = 1.45, p = 0.00), polypharmacy (aOR = 1.55, p = 0.00), and residential care (aOR = 3.92, p = 0.00),... (More)
INTRODUCTION
This study examines medication reviews (MRs) among people living with dementia (PWD) in Sweden, focusing on frequency and factors influencing access.

METHODS
Using nationwide register data, all diagnosed PWD from 2010 to 2016 were assessed for MR receipt in 2015 and/or 2016. The analysis guided by the Andersen healthcare utilization framework, considered predisposing, enabling, and need-based factors through multiple logistic regression.

RESULTS
The MR rate was 16% in 2015, 21% in 2016, and 30% across both years. Increased MR likelihood was linked to higher comorbidity (adjusted odds ratio [aOR] = 1.45, p = 0.00), polypharmacy (aOR = 1.55, p = 0.00), and residential care (aOR = 3.92, p = 0.00), while being married or cohabiting reduced (aOR = 0.80, p = 0.00) MR receipt.

DISCUSSION
Despite national guidelines recommending annual MRs since 2012, rates remain low, especially outside residential care. The findings highlight the need for more equitable MR access for all PWD, particularly those not in residential care.

Highlights
Only 16%–21% of people with dementia received a medication review in 2015–2016 in Sweden.
Higher comorbidity, polypharmacy, and residential care increased likelihood of receiving a medication review.
Being married or cohabiting lowered the chance of receiving a medication review.
Education level and gender did not affect access to medication reviews. (Less)
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author
; ; ; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
medication management, medication review, pharmaceutical review, registry data
in
Alzheimer's & dementia : the journal of the Alzheimer's Association
volume
21
issue
11
article number
e70909
publisher
Wiley
external identifiers
  • pmid:41231424
  • scopus:105021853652
ISSN
1552-5279
DOI
10.1002/alz.70909
language
English
LU publication?
yes
id
1c3154db-3417-4ee7-9945-4c9fa6a4d58d
date added to LUP
2025-11-14 07:50:53
date last changed
2025-12-02 15:50:51
@article{1c3154db-3417-4ee7-9945-4c9fa6a4d58d,
  abstract     = {{INTRODUCTION<br/>This study examines medication reviews (MRs) among people living with dementia (PWD) in Sweden, focusing on frequency and factors influencing access.<br/><br/>METHODS<br/>Using nationwide register data, all diagnosed PWD from 2010 to 2016 were assessed for MR receipt in 2015 and/or 2016. The analysis guided by the Andersen healthcare utilization framework, considered predisposing, enabling, and need-based factors through multiple logistic regression.<br/><br/>RESULTS<br/>The MR rate was 16% in 2015, 21% in 2016, and 30% across both years. Increased MR likelihood was linked to higher comorbidity (adjusted odds ratio [aOR] = 1.45, p = 0.00), polypharmacy (aOR = 1.55, p = 0.00), and residential care (aOR = 3.92, p = 0.00), while being married or cohabiting reduced (aOR = 0.80, p = 0.00) MR receipt.<br/><br/>DISCUSSION<br/>Despite national guidelines recommending annual MRs since 2012, rates remain low, especially outside residential care. The findings highlight the need for more equitable MR access for all PWD, particularly those not in residential care.<br/><br/>Highlights<br/>Only 16%–21% of people with dementia received a medication review in 2015–2016 in Sweden.<br/>Higher comorbidity, polypharmacy, and residential care increased likelihood of receiving a medication review.<br/>Being married or cohabiting lowered the chance of receiving a medication review.<br/>Education level and gender did not affect access to medication reviews.}},
  author       = {{Saha, Sanjib and Persson, Sofie and Jarl, Johan and Trepel, Dominic and Lenander, Cecilia and Londos, Elisabet and Midlöv, Patrik and Lawlor, Brian and Toresson, Håkan and Gerdtham, Ulf-Göran}},
  issn         = {{1552-5279}},
  keywords     = {{medication management; medication review; pharmaceutical review; registry data}},
  language     = {{eng}},
  number       = {{11}},
  publisher    = {{Wiley}},
  series       = {{Alzheimer's & dementia : the journal of the Alzheimer's Association}},
  title        = {{Access of medication review for people living with dementia : An analysis of inequality using Swedish register data}},
  url          = {{http://dx.doi.org/10.1002/alz.70909}},
  doi          = {{10.1002/alz.70909}},
  volume       = {{21}},
  year         = {{2025}},
}