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Self-reported limitations in physical function are common 6 months after out-of-hospital cardiac arrest.

Heimburg, Katarina LU ; Cronberg, Tobias LU ; Tornberg, Åsa LU orcid ; Ullén, Susann ; Friberg, Hans LU ; Nielsen, Niklas LU ; Hassager, Christian ; Horn, Janneke ; Kjærgaard, Jesper and Kuiper, Michael , et al. (2022) In Resuscitation Plus 11. p.1-9
Abstract
Background

Out-of-hospital cardiac arrest (OHCA) survivors generally report good health-related quality of life, but physical aspects of health seem more affected than other domains. Limitations in physical function after surviving OHCA have received little attention.
Aims

To describe physical function 6 months after OHCA and compare it with a group of ST elevation myocardial infarction (STEMI) controls, matched for country, age, sex and time of the cardiac event. A second aim was to explore variables potentially associated with self-reported limitations in physical function in OHCA survivors.
Methods

A cross-sectional sub-study of the Targeted Temperature Management at 33 °C versus 36 °C (TTM) trial with... (More)
Background

Out-of-hospital cardiac arrest (OHCA) survivors generally report good health-related quality of life, but physical aspects of health seem more affected than other domains. Limitations in physical function after surviving OHCA have received little attention.
Aims

To describe physical function 6 months after OHCA and compare it with a group of ST elevation myocardial infarction (STEMI) controls, matched for country, age, sex and time of the cardiac event. A second aim was to explore variables potentially associated with self-reported limitations in physical function in OHCA survivors.
Methods

A cross-sectional sub-study of the Targeted Temperature Management at 33 °C versus 36 °C (TTM) trial with a follow-up 6 months post-event. Physical function was the main outcome assessed with the self-reported Physical Functioning-10 items scale (PF-10). PF-10 is presented as T-scores (0–100), where 50 represents the norm mean. Scores <47 at a group level, or <45 at an individual level indicate limitations in physical function.
Results

287 OHCA survivors and 119 STEMI controls participated. Self-reported physical function by PF-10 was significantly lower for OHCA survivors compared to STEMI controls (mean 46.0, SD 11.2 vs. 48.8, SD 9.0, p = 0.025). 38% of OHCA survivors compared to 26% of STEMI controls reported limitations in physical function at an individual level (p = 0.022). The most predictive variables for self-reported limitations in physical function in OHCA survivors were older age, female sex, cognitive impairment, and symptoms of anxiety and depression after 6 months.
Conclusion

Self-reported limitations in physical function are more common in OHCA survivors compared to STEMI controls.
Trial registration

ClinicalTrials.gov Identifier: NCT01946932. (Less)
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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Cardiac Arrest, Myocardial Infarction, atient Reported Outcome Measures, Physical Function
in
Resuscitation Plus
volume
11
article number
100275
pages
1 - 9
publisher
Elsevier
external identifiers
  • scopus:85134725815
  • pmid:36164471
ISSN
2666-5204
DOI
10.1016/j.resplu.2022.100275
language
English
LU publication?
yes
id
1cdfec53-d2f4-4114-a65b-0ef47979e68e
date added to LUP
2022-08-09 11:23:34
date last changed
2024-04-15 09:08:51
@article{1cdfec53-d2f4-4114-a65b-0ef47979e68e,
  abstract     = {{Background<br/><br/>Out-of-hospital cardiac arrest (OHCA) survivors generally report good health-related quality of life, but physical aspects of health seem more affected than other domains. Limitations in physical function after surviving OHCA have received little attention.<br/>Aims<br/><br/>To describe physical function 6 months after OHCA and compare it with a group of ST elevation myocardial infarction (STEMI) controls, matched for country, age, sex and time of the cardiac event. A second aim was to explore variables potentially associated with self-reported limitations in physical function in OHCA survivors.<br/>Methods<br/><br/>A cross-sectional sub-study of the Targeted Temperature Management at 33 °C versus 36 °C (TTM) trial with a follow-up 6 months post-event. Physical function was the main outcome assessed with the self-reported Physical Functioning-10 items scale (PF-10). PF-10 is presented as T-scores (0–100), where 50 represents the norm mean. Scores &lt;47 at a group level, or &lt;45 at an individual level indicate limitations in physical function.<br/>Results<br/><br/>287 OHCA survivors and 119 STEMI controls participated. Self-reported physical function by PF-10 was significantly lower for OHCA survivors compared to STEMI controls (mean 46.0, SD 11.2 vs. 48.8, SD 9.0, p = 0.025). 38% of OHCA survivors compared to 26% of STEMI controls reported limitations in physical function at an individual level (p = 0.022). The most predictive variables for self-reported limitations in physical function in OHCA survivors were older age, female sex, cognitive impairment, and symptoms of anxiety and depression after 6 months.<br/>Conclusion<br/><br/>Self-reported limitations in physical function are more common in OHCA survivors compared to STEMI controls.<br/>Trial registration<br/><br/>ClinicalTrials.gov Identifier: NCT01946932.}},
  author       = {{Heimburg, Katarina and Cronberg, Tobias and Tornberg, Åsa and Ullén, Susann and Friberg, Hans and Nielsen, Niklas and Hassager, Christian and Horn, Janneke and Kjærgaard, Jesper and Kuiper, Michael and Rylander, Christian and Wise, Matt P. and Lilja, Gisela}},
  issn         = {{2666-5204}},
  keywords     = {{Cardiac Arrest; Myocardial Infarction; atient Reported Outcome Measures; Physical Function}},
  language     = {{eng}},
  pages        = {{1--9}},
  publisher    = {{Elsevier}},
  series       = {{Resuscitation Plus}},
  title        = {{Self-reported limitations in physical function are common 6 months after out-of-hospital cardiac arrest.}},
  url          = {{http://dx.doi.org/10.1016/j.resplu.2022.100275}},
  doi          = {{10.1016/j.resplu.2022.100275}},
  volume       = {{11}},
  year         = {{2022}},
}