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Prophylaxis Escalation in Severe von Willebrand Disease: A Prospective Study from the von Willebrand Disease Prophylaxis Network.

Abshire, T ; Cox-Gill, J ; Kempton, C L ; Leebeek, F W G ; Carcao, M ; Kouides, P ; Donfield, S and Berntorp, Erik LU (2015) In Journal of Thrombosis and Haemostasis 13(9). p.1585-1589
Abstract
Treatment of mucosal bleeding (epistaxis, gastrointestinal and menorrhagia) and joint bleeding remains problematic in clinically severe von Willebrand Disease (VWD). Patients are often unresponsive to treatment (e.g. desmopressin or antifibrinolytic therapy) and may require von Willebrand (VW) factor replacement therapy. There are little data on the use of prophylaxis in VWD and none applied in a prospective, treatment escalation design.
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author
; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Thrombosis and Haemostasis
volume
13
issue
9
pages
1585 - 1589
publisher
Wiley-Blackwell
external identifiers
  • pmid:25930155
  • wos:000360768400007
  • scopus:84940828349
  • pmid:25930155
ISSN
1538-7933
DOI
10.1111/jth.12995
language
English
LU publication?
yes
id
1f514a1c-b0be-4455-9212-6fd07ed9c001 (old id 5461427)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25930155?dopt=Abstract
date added to LUP
2016-04-01 10:44:11
date last changed
2022-05-18 01:30:14
@article{1f514a1c-b0be-4455-9212-6fd07ed9c001,
  abstract     = {{Treatment of mucosal bleeding (epistaxis, gastrointestinal and menorrhagia) and joint bleeding remains problematic in clinically severe von Willebrand Disease (VWD). Patients are often unresponsive to treatment (e.g. desmopressin or antifibrinolytic therapy) and may require von Willebrand (VW) factor replacement therapy. There are little data on the use of prophylaxis in VWD and none applied in a prospective, treatment escalation design.}},
  author       = {{Abshire, T and Cox-Gill, J and Kempton, C L and Leebeek, F W G and Carcao, M and Kouides, P and Donfield, S and Berntorp, Erik}},
  issn         = {{1538-7933}},
  language     = {{eng}},
  number       = {{9}},
  pages        = {{1585--1589}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Journal of Thrombosis and Haemostasis}},
  title        = {{Prophylaxis Escalation in Severe von Willebrand Disease: A Prospective Study from the von Willebrand Disease Prophylaxis Network.}},
  url          = {{http://dx.doi.org/10.1111/jth.12995}},
  doi          = {{10.1111/jth.12995}},
  volume       = {{13}},
  year         = {{2015}},
}