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Risk of inflammatory bowel disease in first- and second-generation immigrants in Sweden: A nationwide follow-up study.

Li, Xinjun LU ; Sundquist, Jan LU ; Hemminki, Kari LU and Sundquist, Kristina LU (2011) In Inflammatory Bowel Diseases 17(8). p.1784-1791
Abstract
BACKGROUND:

The objective was to analyze whether there is an association between country of birth in first-generation immigrants and first hospitalization for an inflammatory bowel disease, and to study whether any such association remains in second-generation immigrants.



METHODS:

In this follow-up study a nationwide research database at Lund University was used to identify all primary hospital diagnoses of Crohn's disease (CD) and ulcerative colitis (UC) in all first- and second-generation immigrants in Sweden between January 1, 1964, and December 31, 2007. Standardized incidence ratios (SIRs) with regard to age, gender, time period, geographical region, and socioeconomic status were estimated in... (More)
BACKGROUND:

The objective was to analyze whether there is an association between country of birth in first-generation immigrants and first hospitalization for an inflammatory bowel disease, and to study whether any such association remains in second-generation immigrants.



METHODS:

In this follow-up study a nationwide research database at Lund University was used to identify all primary hospital diagnoses of Crohn's disease (CD) and ulcerative colitis (UC) in all first- and second-generation immigrants in Sweden between January 1, 1964, and December 31, 2007. Standardized incidence ratios (SIRs) with regard to age, gender, time period, geographical region, and socioeconomic status were estimated in first- and second-generation immigrants.



RESULTS:

No increased but some decreased risks for CD and UC were found among first-generation immigrants. These decreased risks partly remained in the second generation. Moreover, second-generation immigrants of Danish, Eastern European, and Iraqi origin had higher risks of CD than the reference group. Second-generation immigrants of Finnish and Iranian origin had higher risks of UC.



CONCLUSIONS:

Decreased risks of CD and UC found in some first-generation immigrant groups partly persisted in the second generation. For some immigrant groups, increased risks of CD or UC emerged in the second generation. (Inflamm Bowel Dis 2010;). (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Inflammatory Bowel Diseases
volume
17
issue
8
pages
1784 - 1791
publisher
John Wiley & Sons
external identifiers
  • wos:000293235400033
  • pmid:21744434
  • scopus:79960276599
ISSN
1536-4844
DOI
10.1002/ibd.21535
language
English
LU publication?
yes
id
b4dc46c3-bade-40d6-978b-042dfb32126d (old id 2058761)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/21744434?dopt=Abstract
date added to LUP
2011-08-01 19:28:53
date last changed
2017-07-30 04:47:37
@article{b4dc46c3-bade-40d6-978b-042dfb32126d,
  abstract     = {BACKGROUND:<br/><br>
The objective was to analyze whether there is an association between country of birth in first-generation immigrants and first hospitalization for an inflammatory bowel disease, and to study whether any such association remains in second-generation immigrants.<br/><br>
<br/><br>
METHODS:<br/><br>
In this follow-up study a nationwide research database at Lund University was used to identify all primary hospital diagnoses of Crohn's disease (CD) and ulcerative colitis (UC) in all first- and second-generation immigrants in Sweden between January 1, 1964, and December 31, 2007. Standardized incidence ratios (SIRs) with regard to age, gender, time period, geographical region, and socioeconomic status were estimated in first- and second-generation immigrants.<br/><br>
<br/><br>
RESULTS:<br/><br>
No increased but some decreased risks for CD and UC were found among first-generation immigrants. These decreased risks partly remained in the second generation. Moreover, second-generation immigrants of Danish, Eastern European, and Iraqi origin had higher risks of CD than the reference group. Second-generation immigrants of Finnish and Iranian origin had higher risks of UC.<br/><br>
<br/><br>
CONCLUSIONS:<br/><br>
Decreased risks of CD and UC found in some first-generation immigrant groups partly persisted in the second generation. For some immigrant groups, increased risks of CD or UC emerged in the second generation. (Inflamm Bowel Dis 2010;).},
  author       = {Li, Xinjun and Sundquist, Jan and Hemminki, Kari and Sundquist, Kristina},
  issn         = {1536-4844},
  language     = {eng},
  number       = {8},
  pages        = {1784--1791},
  publisher    = {John Wiley & Sons},
  series       = {Inflammatory Bowel Diseases},
  title        = {Risk of inflammatory bowel disease in first- and second-generation immigrants in Sweden: A nationwide follow-up study.},
  url          = {http://dx.doi.org/10.1002/ibd.21535},
  volume       = {17},
  year         = {2011},
}