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Surgical stress response after colorectal resection.

Andersson, Bodil LU ; Ansari, Daniel LU ; Nordén, Morgan LU ; Nilsson, Johan LU and Andersson, Roland LU (2013) In International Surgery 98(4). p.292-299
Abstract
Abstract The human body's response to surgery is correlated with the extent of tissue damage. The aim of the present study was to, over time, map out parameters concerning inflammation, metabolism, nutrition, breathing function, muscle strength, and well-being in elective colorectal surgery. Eighteen patients were prospectively included: colon resection (n = 9) and rectum resection/amputation (n = 9). Postoperative interleukin 10 (IL-10) rose more in the rectum surgery group on day 0 (P = 0.007) and day 3 (P = 0.025). Furthermore, significant differences between groups were detected regarding albumin, prealbumin, and total iron-binding capacity (TIBC). For albumin and TIBC, this difference was seen even on day 7. C-reactive protein, IL-6,... (More)
Abstract The human body's response to surgery is correlated with the extent of tissue damage. The aim of the present study was to, over time, map out parameters concerning inflammation, metabolism, nutrition, breathing function, muscle strength, and well-being in elective colorectal surgery. Eighteen patients were prospectively included: colon resection (n = 9) and rectum resection/amputation (n = 9). Postoperative interleukin 10 (IL-10) rose more in the rectum surgery group on day 0 (P = 0.007) and day 3 (P = 0.025). Furthermore, significant differences between groups were detected regarding albumin, prealbumin, and total iron-binding capacity (TIBC). For albumin and TIBC, this difference was seen even on day 7. C-reactive protein, IL-6, IL-8, glucose, cortisol, insulin, pain, fatigue, nausea, grip strength, and forced expiratory volume in 1 second did not show any differences. No correlation was revealed between measured parameters and postoperative complications. Postoperative levels of IL-10, albumin, prealbumin, and TIBC may be used as determinants of surgical stress after colorectal surgery. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
International Surgery
volume
98
issue
4
pages
292 - 299
publisher
INT COLLEGE OF SURGEONS
external identifiers
  • wos:000327323100004
  • pmid:24229011
  • scopus:84896501767
ISSN
0020-8868
DOI
10.9738/INTSURG-D-12-00009.1
language
English
LU publication?
yes
id
206b517d-b125-4d83-af87-c80632ab8eed (old id 4179373)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24229011?dopt=Abstract
date added to LUP
2013-12-03 19:44:43
date last changed
2019-01-06 08:15:11
@article{206b517d-b125-4d83-af87-c80632ab8eed,
  abstract     = {Abstract The human body's response to surgery is correlated with the extent of tissue damage. The aim of the present study was to, over time, map out parameters concerning inflammation, metabolism, nutrition, breathing function, muscle strength, and well-being in elective colorectal surgery. Eighteen patients were prospectively included: colon resection (n = 9) and rectum resection/amputation (n = 9). Postoperative interleukin 10 (IL-10) rose more in the rectum surgery group on day 0 (P = 0.007) and day 3 (P = 0.025). Furthermore, significant differences between groups were detected regarding albumin, prealbumin, and total iron-binding capacity (TIBC). For albumin and TIBC, this difference was seen even on day 7. C-reactive protein, IL-6, IL-8, glucose, cortisol, insulin, pain, fatigue, nausea, grip strength, and forced expiratory volume in 1 second did not show any differences. No correlation was revealed between measured parameters and postoperative complications. Postoperative levels of IL-10, albumin, prealbumin, and TIBC may be used as determinants of surgical stress after colorectal surgery.},
  author       = {Andersson, Bodil and Ansari, Daniel and Nordén, Morgan and Nilsson, Johan and Andersson, Roland},
  issn         = {0020-8868},
  language     = {eng},
  number       = {4},
  pages        = {292--299},
  publisher    = {INT COLLEGE OF SURGEONS},
  series       = {International Surgery},
  title        = {Surgical stress response after colorectal resection.},
  url          = {http://dx.doi.org/10.9738/INTSURG-D-12-00009.1},
  volume       = {98},
  year         = {2013},
}