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Lack of association between genetic variations in the KALRN region and ischemic stroke

Olsson, Sandra ; Jood, Katarina ; Melander, Olle LU orcid ; Sjögren, Marketa LU ; Norrving, Bo LU ; Nilsson, Michael ; Lindgren, Arne and Jern, Christina (2011) In Clinical Biochemistry 44(12). p.1018-1020
Abstract
Objectives: To investigate whether KALRN gene variation is associated with ischemic stroke (IS). Design and methods: Associations to overall IS and IS subtypes were investigated in SAHLSIS, which comprises 844 patients with IS and 668 controls. Results: Associations between KALRN SNPs and overall IS and cardioembolic stroke were detected. Associations for overall IS were investigated in two additional Swedish samples, but could not be replicated. Conclusion: KALRN gene variation is not associated with overall IS. (C) 2011 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.
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author
; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Single nucleotide polymorphism, Genetics, Ischemic stroke, Kalirin, RhoGEF
in
Clinical Biochemistry
volume
44
issue
12
pages
1018 - 1020
publisher
Elsevier
external identifiers
  • wos:000293043400016
  • scopus:79960289731
  • pmid:21664346
ISSN
1873-2933
DOI
10.1016/j.clinbiochem.2011.05.025
language
English
LU publication?
yes
id
cbfac3fc-5080-46e0-9063-1b22a59f5a41 (old id 2072362)
date added to LUP
2016-04-01 09:50:06
date last changed
2024-01-06 01:08:22
@article{cbfac3fc-5080-46e0-9063-1b22a59f5a41,
  abstract     = {{Objectives: To investigate whether KALRN gene variation is associated with ischemic stroke (IS). Design and methods: Associations to overall IS and IS subtypes were investigated in SAHLSIS, which comprises 844 patients with IS and 668 controls. Results: Associations between KALRN SNPs and overall IS and cardioembolic stroke were detected. Associations for overall IS were investigated in two additional Swedish samples, but could not be replicated. Conclusion: KALRN gene variation is not associated with overall IS. (C) 2011 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.}},
  author       = {{Olsson, Sandra and Jood, Katarina and Melander, Olle and Sjögren, Marketa and Norrving, Bo and Nilsson, Michael and Lindgren, Arne and Jern, Christina}},
  issn         = {{1873-2933}},
  keywords     = {{Single nucleotide polymorphism; Genetics; Ischemic stroke; Kalirin; RhoGEF}},
  language     = {{eng}},
  number       = {{12}},
  pages        = {{1018--1020}},
  publisher    = {{Elsevier}},
  series       = {{Clinical Biochemistry}},
  title        = {{Lack of association between genetic variations in the KALRN region and ischemic stroke}},
  url          = {{http://dx.doi.org/10.1016/j.clinbiochem.2011.05.025}},
  doi          = {{10.1016/j.clinbiochem.2011.05.025}},
  volume       = {{44}},
  year         = {{2011}},
}