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Lack of association between genetic variations in the KALRN region and ischemic stroke

Olsson, Sandra; Jood, Katarina; Melander, Olle LU ; Sjögren, Marketa LU ; Norrving, Bo LU ; Nilsson, Michael; Lindgren, Arne and Jern, Christina (2011) In Clinical Biochemistry 44(12). p.1018-1020
Abstract
Objectives: To investigate whether KALRN gene variation is associated with ischemic stroke (IS). Design and methods: Associations to overall IS and IS subtypes were investigated in SAHLSIS, which comprises 844 patients with IS and 668 controls. Results: Associations between KALRN SNPs and overall IS and cardioembolic stroke were detected. Associations for overall IS were investigated in two additional Swedish samples, but could not be replicated. Conclusion: KALRN gene variation is not associated with overall IS. (C) 2011 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Single nucleotide polymorphism, Genetics, Ischemic stroke, Kalirin, RhoGEF
in
Clinical Biochemistry
volume
44
issue
12
pages
1018 - 1020
publisher
Elsevier
external identifiers
  • wos:000293043400016
  • scopus:79960289731
ISSN
1873-2933
DOI
10.1016/j.clinbiochem.2011.05.025
language
English
LU publication?
yes
id
cbfac3fc-5080-46e0-9063-1b22a59f5a41 (old id 2072362)
date added to LUP
2011-09-02 08:31:30
date last changed
2017-07-23 03:01:04
@article{cbfac3fc-5080-46e0-9063-1b22a59f5a41,
  abstract     = {Objectives: To investigate whether KALRN gene variation is associated with ischemic stroke (IS). Design and methods: Associations to overall IS and IS subtypes were investigated in SAHLSIS, which comprises 844 patients with IS and 668 controls. Results: Associations between KALRN SNPs and overall IS and cardioembolic stroke were detected. Associations for overall IS were investigated in two additional Swedish samples, but could not be replicated. Conclusion: KALRN gene variation is not associated with overall IS. (C) 2011 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.},
  author       = {Olsson, Sandra and Jood, Katarina and Melander, Olle and Sjögren, Marketa and Norrving, Bo and Nilsson, Michael and Lindgren, Arne and Jern, Christina},
  issn         = {1873-2933},
  keyword      = {Single nucleotide polymorphism,Genetics,Ischemic stroke,Kalirin,RhoGEF},
  language     = {eng},
  number       = {12},
  pages        = {1018--1020},
  publisher    = {Elsevier},
  series       = {Clinical Biochemistry},
  title        = {Lack of association between genetic variations in the KALRN region and ischemic stroke},
  url          = {http://dx.doi.org/10.1016/j.clinbiochem.2011.05.025},
  volume       = {44},
  year         = {2011},
}