Bioorganic synthesis, characterization and antioxidant activity of esters of natural phenolics and α-lipoic acid.
Shanker, Shiva LU ; Grey, Carl LU and Adlercreutz, Patrick LU
(2012)
In Journal of Biotechnology
157(2).
p.344-349
- Abstract
- Chemo-enzymatic synthesis of six esters of natural phenolics and α-lipoic acid was carried to produce novel compounds with potential bioactivity. The synthetic route was mild, simple, and efficient with satisfactory yields. The synthesized compounds were screened for antioxidant activities. The prepared derivatives exhibited very good antioxidant activities as determined by DPPH radical scavenging assay and inhibition of lipid oxidation in fish oil emulsion system. Among the prepared derivatives, three compounds exhibited radical scavenging activity similar to the reference antioxidants, BHT and alpha-tocopherol in the DPPH radical scavenging assay, where as in fish oil emulsion system, two derivatives showed activity, which was similar to... (More)
- Chemo-enzymatic synthesis of six esters of natural phenolics and α-lipoic acid was carried to produce novel compounds with potential bioactivity. The synthetic route was mild, simple, and efficient with satisfactory yields. The synthesized compounds were screened for antioxidant activities. The prepared derivatives exhibited very good antioxidant activities as determined by DPPH radical scavenging assay and inhibition of lipid oxidation in fish oil emulsion system. Among the prepared derivatives, three compounds exhibited radical scavenging activity similar to the reference antioxidants, BHT and alpha-tocopherol in the DPPH radical scavenging assay, where as in fish oil emulsion system, two derivatives showed activity, which was similar to the reference antioxidants. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2274597
- author
- Shanker, Shiva
LU
; Grey, Carl
LU
and Adlercreutz, Patrick
LU
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Lipase, Synthesis, Antioxidant, alpha-Lipoic acid, Phenolics
- in
- Journal of Biotechnology
- volume
- 157
- issue
- 2
- pages
- 344 - 349
- publisher
- Elsevier
- external identifiers
-
- wos:000300075100009
- pmid:22138637
- scopus:84855676090
- pmid:22138637
- ISSN
- 1873-4863
- DOI
- 10.1016/j.jbiotec.2011.11.012
- language
- English
- LU publication?
- yes
- id
- 0afe2b1b-407a-4603-a7f8-a71e11472497 (old id 2274597)
- date added to LUP
- 2016-04-01 10:24:16
- date last changed
- 2022-03-12 05:28:59
@article{0afe2b1b-407a-4603-a7f8-a71e11472497,
abstract = {{Chemo-enzymatic synthesis of six esters of natural phenolics and α-lipoic acid was carried to produce novel compounds with potential bioactivity. The synthetic route was mild, simple, and efficient with satisfactory yields. The synthesized compounds were screened for antioxidant activities. The prepared derivatives exhibited very good antioxidant activities as determined by DPPH radical scavenging assay and inhibition of lipid oxidation in fish oil emulsion system. Among the prepared derivatives, three compounds exhibited radical scavenging activity similar to the reference antioxidants, BHT and alpha-tocopherol in the DPPH radical scavenging assay, where as in fish oil emulsion system, two derivatives showed activity, which was similar to the reference antioxidants.}},
author = {{Shanker, Shiva and Grey, Carl and Adlercreutz, Patrick}},
issn = {{1873-4863}},
keywords = {{Lipase; Synthesis; Antioxidant; alpha-Lipoic acid; Phenolics}},
language = {{eng}},
number = {{2}},
pages = {{344--349}},
publisher = {{Elsevier}},
series = {{Journal of Biotechnology}},
title = {{Bioorganic synthesis, characterization and antioxidant activity of esters of natural phenolics and α-lipoic acid.}},
url = {{http://dx.doi.org/10.1016/j.jbiotec.2011.11.012}},
doi = {{10.1016/j.jbiotec.2011.11.012}},
volume = {{157}},
year = {{2012}},
}