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Differing pattern of ambulatory blood pressure in very elderly men expresses dynamics in atherosclerotic load in the senescence.

Siennicki-Lantz, Arkadiusz LU and Elmståhl, Sölve LU (2012) In International Journal of Hypertension 2012(Dec 18).
Abstract
To assess an impact of vascular risk factors on ambulatory blood pressure measurement (ABPM) in the elderly, we followed up a population-based cohort of men from 68 until 82 years, when 104 survivors underwent ABPM. Results. At age 68, hypertension and high clinic blood pressure (CBP) did not predict ABPM level. Smoking and low ankle-brachial index (ABI) predicted higher ABPM variability and pulse pressure (PP), but not absolute ABPM values. At age 82, hypertension, high or increasing CBP, strongly positively correlated with all variables of ABPM. Carotid stenosis, low or declining ABI during followup, correlated with higher nocturnal ABPM and PP. Concluding. Hypertension and vascular risk factors in a cohort of 68-year-old men do not... (More)
To assess an impact of vascular risk factors on ambulatory blood pressure measurement (ABPM) in the elderly, we followed up a population-based cohort of men from 68 until 82 years, when 104 survivors underwent ABPM. Results. At age 68, hypertension and high clinic blood pressure (CBP) did not predict ABPM level. Smoking and low ankle-brachial index (ABI) predicted higher ABPM variability and pulse pressure (PP), but not absolute ABPM values. At age 82, hypertension, high or increasing CBP, strongly positively correlated with all variables of ABPM. Carotid stenosis, low or declining ABI during followup, correlated with higher nocturnal ABPM and PP. Concluding. Hypertension and vascular risk factors in a cohort of 68-year-old men do not result in higher ABPM at age 82, possibly due to inflection point in their pressure development. Higher ABPM reflects instead an increasing CBP and aggravating atherosclerosis during the preceding decade in that part of the cohort with previously favorable risk factor status. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
International Journal of Hypertension
volume
2012
issue
Dec 18
publisher
Hindawi Publishing Corporation
external identifiers
  • pmid:22216405
  • scopus:84866184927
ISSN
2090-0392
DOI
10.1155/2012/417291
language
English
LU publication?
yes
id
f9dc6bfd-a1e0-483e-8d03-d61e6d41c91d (old id 2336717)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/22216405?dopt=Abstract
date added to LUP
2012-02-01 19:22:16
date last changed
2017-01-01 03:06:18
@article{f9dc6bfd-a1e0-483e-8d03-d61e6d41c91d,
  abstract     = {To assess an impact of vascular risk factors on ambulatory blood pressure measurement (ABPM) in the elderly, we followed up a population-based cohort of men from 68 until 82 years, when 104 survivors underwent ABPM. Results. At age 68, hypertension and high clinic blood pressure (CBP) did not predict ABPM level. Smoking and low ankle-brachial index (ABI) predicted higher ABPM variability and pulse pressure (PP), but not absolute ABPM values. At age 82, hypertension, high or increasing CBP, strongly positively correlated with all variables of ABPM. Carotid stenosis, low or declining ABI during followup, correlated with higher nocturnal ABPM and PP. Concluding. Hypertension and vascular risk factors in a cohort of 68-year-old men do not result in higher ABPM at age 82, possibly due to inflection point in their pressure development. Higher ABPM reflects instead an increasing CBP and aggravating atherosclerosis during the preceding decade in that part of the cohort with previously favorable risk factor status.},
  articleno    = {417291},
  author       = {Siennicki-Lantz, Arkadiusz and Elmståhl, Sölve},
  issn         = {2090-0392},
  language     = {eng},
  number       = {Dec 18},
  publisher    = {Hindawi Publishing Corporation},
  series       = {International Journal of Hypertension},
  title        = {Differing pattern of ambulatory blood pressure in very elderly men expresses dynamics in atherosclerotic load in the senescence.},
  url          = {http://dx.doi.org/10.1155/2012/417291},
  volume       = {2012},
  year         = {2012},
}